Arachidonate 5-lipoxygenase and its new inhibitors

2,3,5-Trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-l,4-benzoquinone (AA861), a selective inhibitor of the 5-lipoxygenase reaction and the biosynthesis of slow-reacting substance of anaphylaxis

1982 • 251 citations

Arachidonate 5-lipoxygenase of guinea pig peritoneal polymorphonuclear leukocytes. Activation by adenosine 5'-triphosphate.

1983 • 215 citations

Enzymatic assembly of slow reacting substance

1980 • 122 citations

Arachidonate 12-lipoxygenase of porcine leukocyte with activity for 5-hydroxyeicosatetraenoic acid

1982 • 118 citations

Pharmacological profile of AA-861, A 5-lipoxygenase inhibitor

1983 • 111 citations

Selective inhibition of 5‐lipoxygenase by natural compounds isolated from Chinese plants, Artemisia rubripes Nakai

1983 • 78 citations

Irreversible inhibition of prostaglandin and leukotriene biosynthesis from arachidonic acid by 11,12-dehydro- and 5,6-dehydroarachidonic acids, respectively

1982 • 53 citations

Inhibition of human neutrophil arachidonate 5-lipoxygenase by 6, 9-deepoxy-6, 9-(phenylimino)- Δ 6, 8-prostaglandin I1 (U-60257)

1983 • 46 citations

Specific inhibition and oxidative regulation of 5-lipoxygenase.

1983 • 42 citations

Synthesis and 5-lipoxygenase inhibitory activities of eicosanoid compounds

1983 • 42 citations

INHIBITION OF HYPERSENSITIVITY REACTIONS BY SOLUBLE DERIVATIVES OF BAICALEIN

1975 • 41 citations

Effect of Rutin on Anaphylactic and Histamine Shock

1947 • 34 citations

Selective inhibition of 5‐lipoxygenase by 5,6‐methanoleukotriene A₄, a stable analogue of leukotriene A₄

1982 • 30 citations

Irreversible inhibition of the leukotriene pathway by 4,5-dehydroarachidonic acid

1983 • 20 citations

Inhibition of Hypersensitivity Reactions by Soluble Derivatives of Baicalein

1975 • 3 citations

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