TPR-MET oncogenic rearrangement: detection by polymerase chain reaction amplification of the transcript and expression in human tumor cell lines.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1987 • 2,045 citations

Prevalence of ras gene mutations in human colorectal cancers

1987 • 1,866 citations

The Chromosomal Basis of Human Neoplasia

1983 • 1,121 citations

A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine

1987 • 1,021 citations

Molecular cloning of a new transforming gene from a chemically transformed human cell line

1984 • 966 citations

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

1984 • 913 citations

Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

1983 • 848 citations

The Chronic Myelogenous Leukemia-Specific P210 Protein Is the Product of the bcr / abl Hybrid Gene

1986 • 820 citations

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

1986 • 795 citations

Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro.

1988 • 741 citations

Molecular Cloning of the Chromosomal Breakpoint of B-Cell Lymphomas and Leukemias with the t(11;14) Chromosome Translocation

1984 • 671 citations

Mechanism of met oncogene activation

1986 • 551 citations

Tyrosine kinase receptor indistinguishable from the c-met protein

1989 • 496 citations

Nonrandom chromosome abnormalities in acute leukemia and dysmyelopoietic syndromes in patients with previously treated malignant disease

1981 • 451 citations

Clustering of breakpoints on chromosome 11 in human B-cell neoplasms with the t(11 ; 14) chromosome translocation

1985 • 446 citations

Detection of Minimal Residual Cells Carrying the t(14;18) by DNA Sequence Amplification

1987 • 426 citations

Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes.

1988 • 367 citations

Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease.

1988 • 341 citations

The human met oncogene is related to the tyrosine kinase oncogenes

1985 • 295 citations

Rearrangement and amplification of c-abl sequences in the human chronic myelogenous leukemia cell line K-562.

1983 • 244 citations

Chromosome pattern, occupation, and clinical features in patients with acute nonlymphocytic leukemia

1981 • 235 citations

Cultivation in vitro of cells derived from a human osteosarcoma

1971 • 218 citations

There are differences in cytogenetic abnormalities among histologic subtypes of the non-Hodgkin's lymphomas

1985 • 178 citations

Characterization of c-Ki-ras oncogene alleles by direct sequencing of enzymatically amplified DNA from carcinogen-induced tumors.

1987 • 135 citations

Characterization of human transforming genes from chemically transformed, teratocarcinoma, and pancreatic carcinoma cell lines.

1984 • 105 citations

Transformation of human cells in culture by N-methyl-N′-nitro-N-nitrosoguanidine

1975 • 104 citations

A one tube reaction for the synthesis of blunt-ended double-stranded cDNA

1988 • 63 citations

Characterization of the Rearranged tpr-met Oncogene Breakpoint

1987 • 53 citations

Transformation of Human Osteosarcoma Cells by a Chemical Carcinogen2

1975 • 35 citations

Primary structure of the met protein tyrosine kinase domain.

1987 • 29 citations

Activation of the met oncogene in the human MNNG-HOS cell line involves a chromosomal rearrangement

1986 • 26 citations

Chronic myelogenous leukemia with a complex Ph1 translocation in an XYY male

1984 • 17 citations

Chemical transformation of human revertant cells induced by murine sarcoma virus

1978 • 6 citations