Pore‐forming activity is not sufficient for Legionella pneumophila phagosome trafficking and intracellular growth

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii

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Legionnaires' Disease

1977 • 1,687 citations

Legionnaires' Disease

1977 • 1,199 citations

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

1990 • 1,150 citations

RESPONSE OF CULTURED MACROPHAGES TO MYCOBACTERIUM TUBERCULOSIS, WITH OBSERVATIONS ON FUSION OF LYSOSOMES WITH PHAGOSOMES

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Conjugative Transfer by the Virulence System of Legionella pneumophila

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The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes.

1983 • 704 citations

Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus

1994 • 676 citations

Charcoal-yeast extract agar: primary isolation medium for Legionella pneumophila

1979 • 655 citations

Legionnaires' Disease Bacterium (Legionella pneumophila) Multiplies Intracellularly in Human Monocytes

1980 • 648 citations

Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes.

1983 • 644 citations

Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila

1993 • 633 citations

Association of Legionella pneumophila with the macrophage endoplasmic reticulum

1995 • 556 citations

Host cell killing and bacterial conjugation require overlapping sets of genes within a 22-kb region of the Legionella pneumophila genome

1998 • 530 citations

A series of wide-host-range low-copy-number vectors that allow direct screening for recombinants

1991 • 501 citations

Evidence for a gamma-interferon receptor that regulates macrophage tumoricidal activity.

1984 • 471 citations

Legionella pneumophila inhibits acidification of its phagosome in human monocytes.

1984 • 384 citations

Legionella pneumophila DotA protein is required for early phagosome trafficking decisions that occur within minutes of bacterial uptake

1998 • 360 citations

Identification of Legionella pneumophila genes required for growth within and killing of human macrophages

1993 • 357 citations

Trans-complementation-dependent replication of a low molecular weight origin fragment from plasmid R6K

1978 • 356 citations

Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages.

1992 • 310 citations

The invasion‐associated type III system of Salmonella typhimurium directs the translocation of Sip proteins into the host cell

1997 • 300 citations

Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages.

1992 • 277 citations

Altered intracellular targeting properties associated with mutations in the Legionella pneumophila dotA gene

1994 • 248 citations

Evidence for pore‐forming ability by Legionella pneumophila

1998 • 227 citations

Customized secretion chaperones in pathogenic bacteria

1996 • 209 citations

Identification of Linked Legionella pneumophila Genes Essential for Intracellular Growth and Evasion of the Endocytic Pathway

1998 • 201 citations

Adaptation of a conjugal transfer system for the export of pathogenic macromolecules

1996 • 188 citations

Icm/Dot‐dependent upregulation of phagocytosis by Legionella pneumophila

2001 • 188 citations

Analysis of the Legionella pneumophila fliI gene: intracellular growth of a defined mutant defective for flagellum biosynthesis

1997 • 186 citations

The Legionella pneumophila icm locus: a set of genes required for intracellular multiplication in human macrophages

1994 • 182 citations

Characterization of a new region required for macrophage killing by Legionella pneumophila

1997 • 166 citations

Requirement for exported proteins in secretion through the invasion-associated type III system of Salmonella typhimurium

1996 • 152 citations

The Legionella pneumophila PilT Homologue DotB Exhibits ATPase Activity That Is Critical for Intracellular Growth

2004 • 142 citations

The adenovirus E4-6/7 protein transactivates the E2 promoter by inducing dimerization of a heteromeric E2F complex.

1994 • 136 citations

Growth of Legionella pneumophila in a human macrophage-like (U937) cell line

1988 • 126 citations

Early Events in Phagosome Establishment Are Required for Intracellular Survival of Legionella pneumophila

1998 • 124 citations

Topology of Legionella pneumophila DotA: an inner membrane protein required for replication in macrophages

1997 • 124 citations

Identification of Legionella pneumophila mutants that have aberrant intracellular fates

1996 • 122 citations

Lysosome-associated membrane proteins: Characterization of LAMP-1 of macrophage P388 and mouse embryo 3T3 cultured cells

1985 • 118 citations

Genetic Responses to Free Radicals: Homeostasis and Gene Control

2000 • 112 citations

The Legionella pneumophila IcmS–LvgA protein complex is important for Dot/Icm‐dependent intracellular growth

2006 • 100 citations

Subcellular localization of seven VirB proteins of Agrobacterium tumefaciens: implications for the formation of a T-DNA transport structure

1993 • 94 citations

Expression of contact-dependent cytolytic activity by Mycobacterium tuberculosis and isolation of the genomic locus that encodes the activity

1993 • 87 citations

Isolation and characterization of auxotrophic mutants of Legionella pneumophila that fail to multiply in human monocytes

1988 • 75 citations

Localization and Topology of VirB Proteins of Agrobacterium tumefaciens

1994 • 73 citations

Use of Salt to Isolate Legionella pneumophila Mutants Unable to Replicate in Macrophages

1996 • 70 citations

Cytotoxicity of extracellular Legionella pneumophila

1994 • 51 citations