Analogs of human epidermal growth factor which partially inhibit the growth factor-dependent protein-tyrosine kinase activity of the epidermal growth factor receptor

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

GROWTH FACTOR RECEPTOR TYROSINE KINASES

1988 • 1,841 citations

RECEPTORS FOR EPIDERMAL GROWTH FACTOR AND OTHER POLYPEPTIDE MITOGENS

1987 • 1,274 citations

Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor

1987 • 624 citations

Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor

1987 • 609 citations

Self-phosphorylation of epidermal growth factor receptor: evidence for a model of intermolecular allosteric activation

1987 • 508 citations

Signal transduction by allosteric receptor oligomerization

1988 • 410 citations

Allosteric regulation of the epidermal growth factor receptor kinase.

1986 • 381 citations

Molecular mechanisms of transmembrane signalling

1985 • 352 citations

Synthetic tyrosine polymers as substrates and inhibitors of tyrosine-specific protein kinases.

1984 • 246 citations

Mechanism of epidermal growth factor receptor autophosphorylation and high-affinity binding.

1987 • 209 citations

A mutant epidermal growth factor receptor with defective protein tyrosine kinase is unable to stimulate proto-oncogene expression and DNA synthesis.

1987 • 186 citations

Epidermal growth factor binding induces a conformational change in the external domain of its receptor.

1989 • 175 citations

Growth factor control of epidermal growth factor receptor kinase activity via an intramolecular mechanism.

1988 • 98 citations

Use of tyrosine‐containing polymers to characterize the substrate specificity of insulin and other hormone‐stimulated tyrosine kinases

1985 • 94 citations

Intrapeptide autophosphorylation of the epidermal growth factor receptor: regulation of kinase catalytic function by receptor dimerization

1985 • 90 citations

42,000-molecular weight EGF receptor has protein kinase activity

1984 • 85 citations

Cloning of authentic human epidermal growth factor as a bacterial secretory protein and its initial structure-function analysis by site-directed mutagenesis.

1988 • 71 citations