Correlated resistance to glucose deprivation and cytotoxic agents in fibroblast cell lines from long-lived pituitary dwarf mice
Data up to Jan 2025
Total Citations Per Year
Abstract
References (43)
Free radicals in biology and medicine
1991 • 17,840 citations
Free Radicals in Biology and Medicine
1990 • 4,962 citations
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
2002 • 2,057 citations
Tetrazolium dyes as tools in cell biology: New insights into their cellular reduction
2005 • 2,027 citations
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
2002 • 1,506 citations
The Endocrine Regulation of Aging by Insulin-like Signals
2003 • 1,342 citations
Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase
2001 • 921 citations
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production
2001 • 814 citations
A Combined Assay of Cell Viability and in Vitro Cytotoxicity with a Highly Water-Soluble Tetrazolium Salt, Neutral Red and Crystal Violet.
1996 • 719 citations
Mitochondrial Binding of Hexokinase II Inhibits Bax-induced Cytochrome c Release and Apoptosis
2002 • 657 citations
Multifaceted roles of glycolytic enzymes
2005 • 641 citations
Growth Factors Can Influence Cell Growth and Survival through Effects on Glucose Metabolism
2001 • 521 citations
Deletion, But Not Antagonism, of the Mouse Growth Hormone Receptor Results in Severely Decreased Body Weights, Insulin, and Insulin-Like Growth Factor I Levels and Increased Life Span
2003 • 504 citations
The Biochemical and Cellular Basis of Cell Proliferation Assays That Use Tetrazolium Salts
1996 • 376 citations
Physiological roles of nicotinamide nucleotide transhydrogenase
1988 • 348 citations
Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions
2000 • 324 citations
Akt and Bcl-xL Promote Growth Factor-independent Survival through Distinct Effects on Mitochondrial Physiology
2001 • 309 citations
Delayed Occurrence of Fatal Neoplastic Diseases in Ames Dwarf Mice: Correlation to Extended Longevity
2003 • 297 citations
Akt Inhibits Apoptosis Downstream of BID Cleavage via a Glucose-Dependent Mechanism Involving Mitochondrial Hexokinases
2003 • 284 citations
A mechanism of paraquat toxicity in mice and rats
1976 • 253 citations
Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress
2005 • 248 citations
Potential role of nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase in apoptosis and oxidative stress
2001 • 215 citations
Multiplex stress resistance in cells from long‐lived dwarf mice
2003 • 213 citations
Genes That Prolong Life: Relationships of Growth Hormone and Growth to Aging and Life Span
2001 • 182 citations
Glucose transport and apoptosis.
2000 • 157 citations
Evidence That Ames Dwarf Mice Age Differently from Their Normal Siblings in Behavioral and Learning and Memory Parameters
2001 • 152 citations
Hormone-Treated Snell Dwarf Mice Regain Fertility But Remain Long Lived and Disease Resistant
2004 • 149 citations
Cell surface oxygen consumption by mitochondrial gene knockout cells
2004 • 109 citations
CHOP plays a pivotal role in the astrocyte death induced by oxygen and glucose deprivation
2005 • 102 citations
Dissociation of Akt1 from its negative regulator JIP1 is mediated through the ASK1–MEK–JNK signal transduction pathway during metabolic oxidative stress
2005 • 69 citations
Activation of ERK during DNA damage-induced apoptosis involves protein kinase Cδ
2005 • 68 citations
Identification of Cytochrome-b5 Reductase as the Enzyme Responsible for NADH-Dependent Lucigenin Chemiluminescence in Human Spermatozoa1
2005 • 61 citations
An Evaluation of Three New-Generation Tetrazolium Salts for the Measurement of Respiratory Activity in Activated Sludge Microorganisms
2005 • 55 citations
The PKC delta inhibitor, rottlerin, induces apoptosis of haematopoietic cell lines through mitochondrial membrane depolarization and caspases' cascade
2005 • 51 citations
An aging-related cell surface NADH oxidase (arNOX) generates superoxide and is inhibited by coenzyme Q.
2003 • 48 citations
Multiple proteins with single activities or a single protein with multiple activities: The conundrum of cell surface NADH oxidoreductases
2005 • 47 citations
Announcement: Four-Way Cross Mouse Stocks: A New, Genetically Heterogeneous Resource for Aging Research
1999 • 38 citations
Dominant-negative Jun N-terminal protein kinase (JNK-1) inhibits metabolic oxidative stress during glucose deprivation in a human breast carcinoma cell line
2000 • 32 citations
Transient glucose deprivation causes upregulation of heme oxygenase-1 and cyclooxygenase-2 expression in cardiac fibroblasts
2004 • 30 citations
Involvement of proteolytic activation of PKCδ in cisplatin-induced apoptosis in human small cell lung cancer H69 cells
2005 • 29 citations
Role of MAPK/ERK1/2 in the glucose deprivation-induced death in immunostimulated astroglia
2004 • 27 citations
PKCδ and mTOR interact to regulate stress and IGF-I induced IRS-1 Ser312 phosphorylation in breast cancer cells
2005 • 17 citations
A 96-Well Surrogate Survival Assay Coupled with a Special Short Interfering RNA Vector for Assessing Cancer Gene Targets with Enhanced Signal/Noise Ratio and Its Utility in HTS for Cancer Therapeutic Targets
2005 • 12 citations