Effects of Hypertension, Diabetes Mellitus, and Hypercholesterolemia on Endothelin Type B Receptor–Mediated Nitric Oxide Release From Rat Kidney

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Cloning and expression of a cDNA encoding an endothelin receptor

1990 • 2,590 citations

Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

1990 • 2,432 citations

Prevention of diabetic glomerulopathy by pharmacological amelioration of glomerular capillary hypertension.

1986 • 1,210 citations

Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes.

1991 • 1,161 citations

Elevated blood pressure and craniofaclal abnormalities in mice deficient in endothelin-1

1994 • 1,002 citations

Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells.

1993 • 576 citations

Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788.

1994 • 574 citations

Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist

1993 • 529 citations

Both ETA and ETB receptors mediate contraction to endothelin-1 in human blood vessels.

1994 • 521 citations

Impaired contraction and relaxation in aorta from streptozotocin-diabetic rats: Role of polyol pathway

1992 • 216 citations

Mechanisms of Adrenomedullin-Induced Vasodilation in the Rat Kidney

1995 • 201 citations

Lysophosphatidylcholine: Essential role in the inhibition of endothelium-dependent vasorelaxation by oxidized low density lipoprotein

1990 • 187 citations

Immunocytochemical localization of distinct isoforms of nitric oxide synthase in the juxtaglomerular apparatus of normal rat kidney.

1994 • 185 citations

SB 209670, a rationally designed potent nonpeptide endothelin receptor antagonist.

1994 • 165 citations

Circulating and tissue endothelin immunoreactivity in hypercholesterolemic pigs.

1993 • 161 citations

Bradykinin inhibition of EGF- and PDGF-induced DNA synthesis in human fibroblasts

1993 • 139 citations

Endothelial Dysfunction and Cardiorenal Injury in Experimental Salt-Sensitive Hypertension

1997 • 129 citations

Direct and sympathetically mediated venoconstriction in essential hypertension. Enhanced responses to endothelin-1.

1994 • 108 citations

The Cardiac Renin-Angiotensin System in STZ-Induced Diabetes

1994 • 106 citations

Real time measurement of nitric oxide produced ex vivo by luminol-H2O2 chemiluminescence method.

1993 • 102 citations

Enhanced Endothelin-Mediated Coronary Vasoconstriction and Attenuated Basal Nitric Oxide Activity in Experimental Hypercholesterolemia

1997 • 102 citations

Production of endothelin-1 from the mesenteric arteries of streptozotocin-induced diabetic rats

1991 • 98 citations

Direct Measurements of Endothelium-Derived Nitric Oxide Release by Stimulation of Endothelin Receptors in Rat Kidney and Its Alteration in Salt-Induced Hypertension

1995 • 94 citations

Angiotensin converting enzyme inhibition modulates endogenous endothelin in chronic canine thoracic inferior vena caval constriction.

1996 • 68 citations

Level of ETB receptor mRNA is down-regulated by endothelins through decreasing the intracellular stability of mRNA molecules

1992 • 59 citations

Antiatherosclerotic Effects of the Angiotensin-Converting Enzyme Inhibitors Captopril and Fosinopril in Hypercholesterolemic Minipigs

1994 • 47 citations

Receptor Subtype for Vasopressin-Induced Release of Nitric Oxide From Rat Kidney

1997 • 26 citations

Regular immunohistochemical localization of endothelin‐1 and endothelin‐B receptor in normal, hyperplastic and neoplastic human adrenocortical cells

1997 • 23 citations

Does endothelin work as an intrarenal mechanism to alter pressure natriuresis in spontaneously hypertensive rats?

1994 • 17 citations

SYSTEMIC AND REGIONAL EFFECTS OF ENDOTHELIN IN RABBITS: EFFECTS OF ENDOTHELIN ANTIBODY

1990 • 15 citations