A new model for microtubule‐associated protein (MAP)‐induced microtubule assembly

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Cleavage of structural proteins during the assemble of the head of bacterio-phage T4

1970 • 5,738 citations

Dynamic instability of microtubule growth

1984 • 3,187 citations

A protein factor essential for microtubule assembly.

1975 • 2,863 citations

Microtubule Assembly in the Absence of Added Nucleotides

1973 • 2,055 citations

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau.

1988 • 1,073 citations

Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin

1977 • 878 citations

The Primary Structure and Heterogeneity of Tau Protein from Mouse Brain

1988 • 671 citations

Domains of tau Protein and Interactions with Microtubules

1994 • 630 citations

Thermodynamics of the polymerization of protein

1975 • 596 citations

Structure and novel exons of the human .tau. gene

1992 • 587 citations

Tau Consists of a Set of Proteins with Repeated C-Terminal Microtubule-Binding Domains and Variable N-Terminal Domains

1989 • 478 citations

Microtubule-Associated Protein MAP2 Shares a Microtubule Binding Motif with Tau Protein

1988 • 476 citations

Microtubule-associated proteins and the stimulation of tubulin assembly in vitro

1976 • 434 citations

Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau

1994 • 391 citations

Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains.

1989 • 321 citations

The microtubule binding domain of microtubule-associated protein MAP1B contains a repeated sequence motif unrelated to that of MAP2 and tau.

1989 • 294 citations

Functional organization of microtubule-associated protein tau. Identification of regions which affect microtubule growth, nucleation, and bundle formation in vitro.

1993 • 219 citations

Protofilaments and rings, two conformations of the tubulin family conserved from bacterial FtsZ to alpha/beta and gamma tubulin.

1996 • 179 citations

The kinetics of microtubule assembly. Evidence for a two-stage nucleation mechanism.

1984 • 179 citations

Two Separate 18-Amino Acid Domains of Tau Promote the Polymerization of Tubulin

1989 • 167 citations

Molecular Structure and Function of Microtubule-Associated Proteins

1991 • 166 citations

Domains of Neuronal Microtubule-associated Proteins and Flexural Rigidity of Microtubules

1997 • 166 citations

Studies on the expression of the microtubule-associated protein, tau, during mouse brain development, with newly isolated complementary DNA probes.

1984 • 164 citations

Taxol-induced flexibility of microtubules and its reversal by MAP-2 and Tau.

1993 • 149 citations

Non-neuronal 210×103Mr microtubule-associated protein (MAP4) contains a domain homologous to the microtubule-binding domains of neuronal MAP2 and tau

1991 • 136 citations

A model for microtubule-associated protein 4 structure. Domains defined by comparisons of human, mouse, and bovine sequences.

1991 • 127 citations

Removal of the projections from cytoplasmic microtubules in vitro by digestion with trypsin.

1977 • 123 citations

Molecular cloning of a ubiquitously distributed microtubule-associated protein with Mr 190,000.

1990 • 122 citations

Conversion of Serine to Aspartate Imitates Phosphorylation-induced Changes in the Structure and Function of Microtubule-associated Protein Tau

1997 • 122 citations

A Common Amino Acid Sequence in 190-kDa Microtubule-associated Protein and Tau for the Promotion of Microtubule Assembly

1989 • 121 citations

Microtubule-associated proteins 1A and LC2. Two proteins encoded in one messenger RNA.

1992 • 113 citations

Molecular structure of microtubule-associated protein 2b and 2c from rat brain.

1990 • 111 citations

MAP 4: occurrence in mouse tissues.

1984 • 107 citations

Functional analyses of the domain structure of microtubule-associated protein-4 (MAP-U)

1991 • 100 citations

The microtubule-binding fragment of microtubule-associated protein-2: location of the protease-accessible site and identification of an assembly-promoting peptide.

1989 • 98 citations

Genomic structure of human microtubule-associated protein 2 (MAP-2) and characterization of additional MAP-2 isoforms.

1995 • 79 citations

Microtubule-binding domain of tau proteins.

1988 • 66 citations

Sequence analysis of MAP2 function in living cells

1994 • 63 citations

Site-specific phosphorylation by protein kinase C inhibits assembly-promoting activity of microtubule-associated protein 4

1991 • 42 citations

The mechanism of equilibrium binding of microtubule-associated protein 2 to microtubules. Binding is a multi-phasic process and exhibits positive cooperativity

1993 • 39 citations

Non-cooperative Binding of the MAP-2 Microtubule-binding Region to Microtubules

1995 • 35 citations

Limited chymotryptic digestion of bovine adrenal 190,000-Mr microtubule-associated protein and preparation of a 27,000-Mr fragment which stimulates microtubule assembly.

1987 • 34 citations

Exploring the Microtubule-Binding Region of Bovine Microtubule-Associated Protein-2 (MAP-2): cDNA Sequencing, Bacterial Expression, and Site-Directed Mutagenesis

1994 • 16 citations

The `assembly‐promoting sequence region' of microtubule‐associated protein 4 failed to promote microtubule assembly

1997 • 8 citations