Translocation of long peptides by transporters associated with antigen processing (TAP)

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES

1985 • 4,790 citations

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1994 • 2,480 citations

Antigen Recognition by Class I-Restricted T Lymphocytes

1989 • 1,207 citations

Peptides Naturally Presented by MHC Class I Molecules

1993 • 803 citations

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters

1990 • 717 citations

[6] Preparation of microsomal membranes for cotranslational protein translocation

1983 • 679 citations

A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

1990 • 644 citations

Selective and ATP-Dependent Translocation of Peptides by the MHC-Encoded Transporter

1993 • 556 citations

MHC Class I Expression in Mice Lacking the Proteasome Subunit LMP-7

1994 • 520 citations

Altered peptidase and viral-specific T cell response in LMP2 mutant mice

1994 • 450 citations

Transport Protein Genes in the Murine MHC: Possible Implications for Antigen Processing

1990 • 438 citations

Impaired assembly and transport of HLA-A and -B antigens in a mutant TxB cell hybrid.

1986 • 437 citations

GENERATION, TRANSLOCATION, AND PRESENTATION OF MHC CLASS I-RESTRICTED PEPTIDES

1995 • 428 citations

MHC class II region encoding proteins related to the muKidrug resistance family of transmembrane transporters

1990 • 426 citations

Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter

1991 • 413 citations

Structure of Peptides Associated with Class I and Class II MHC Molecules

1994 • 381 citations

TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective

1993 • 365 citations

MHC class l/β2-microglobulin complexes associate with TAP transporters before peptide binding

1994 • 356 citations

Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule

1992 • 344 citations

Selectivity of MHC-encoded peptide transporters from human, mouse and rat

1994 • 339 citations

Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter

1991 • 329 citations

Interaction of MHC Class I Molecules with the Transporter Associated with Antigen Processing

1994 • 300 citations

A sequential model for peptide binding and transport by the transporters associated with antigen processing

1994 • 290 citations

Evidence that transporters associated with antigen processing translocate a major histocompatibility complex class I-binding peptide into the endoplasmic reticulum in an ATP-dependent manner.

1993 • 266 citations

Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation

1992 • 250 citations

Alleles and haplotypes of the MHC-encoded ABC transporters TAP1 and TAP2

1993 • 217 citations

Peptide size selection by the major histocompatibility complex-encoded peptide transporter.

1994 • 212 citations

Peptide length and sequence specificity of the mouse TAP1/TAP2 translocator.

1994 • 207 citations

Dependence of Peptide Binding by MHC Class I Molecules on Their Interaction with TAP

1995 • 189 citations

Peptide Translocation by Variants of the Transporter Associated with Antigen Processing

1993 • 188 citations

Human transporters associated with antigen processing possess a promiscuous peptide-binding site

1994 • 178 citations

Trimming of antigenic peptides in an early secretory compartment.

1994 • 169 citations

Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum.

1995 • 163 citations

A subset of HLA-B27 molecules contains peptides muchlonger than nonamers.

1994 • 161 citations

Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences.

1995 • 155 citations

Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling.

1994 • 151 citations

Characteristics of peptide and major histocompatibility complex class I/beta 2-microglobulin binding to the transporters associated with antigen processing (TAP1 and TAP2).

1994 • 150 citations

Primary structural requirements for N‐glycosylation of peptides in rat liver

1979 • 124 citations

Isolation and identification of two hemolytic forms of streptolysin-O

1984 • 112 citations

Requirements for Peptide Binding to the Human Transporter Associated with Antigen Processing Revealed by Peptide Scans and Complex Peptide Libraries

1995 • 110 citations

Analysis of the fine specificity of rat, mouse and human TAP peptide transporters

1995 • 102 citations

Peptide selection by MHC-encoded TAP transporters

1994 • 101 citations

Novel dipeptide aldehydes are proteasome inhibitors and block the MHC-I antigen-processing pathway.

1995 • 99 citations

Substrate specificity of allelic variants of the TAP peptide transporter

1994 • 95 citations

TAP polymorphism does not influence transport of peptide variants in mice and humans

1995 • 94 citations

Supply and transport of peptides presented by class I MHC molecules

1995 • 91 citations

Residues in TAP2 peptide transporters controlling substrate specificity.

1996 • 77 citations

Identification of a contact region for peptide on the TAP1 chain of the transporter associated with antigen processing.

1996 • 75 citations

Characteristics of peptide and class I/b2m binding to the transporters associated with antigen processing (TAP. 1 and TAP. 2)

1994 • 59 citations

Characterization of an incompletely assembled major histocompatibility class I molecule (H-2Kb) associated with unusually long peptides: implications for antigen processing and presentation.

1994 • 48 citations

Circular dichroism studies of synthetic Asn-X-Ser/Thr-containing peptides: Structure-glycosylation relationship

1981 • 41 citations