Homozygous deletion and frequent allelic loss of the 21q11.1-q21.1 region including theANA gene in human lung carcinoma

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

1997 • 4,753 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Identification of the breast cancer susceptibility gene BRCA2

1995 • 3,581 citations

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1986 • 2,968 citations

A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types

1994 • 2,821 citations

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1997 • 2,746 citations

DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1

1996 • 2,320 citations

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

1990 • 1,882 citations

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

1994 • 1,806 citations

Identification of BTG2, an antiproliferative p53–dependent component of the DNA damage cellular response pathway

1996 • 416 citations

Allelotype of pancreatic adenocarcinoma using xenograft enrichment.

1995 • 308 citations

BTG1, a member of a new family of antiproliferative genes.

1992 • 298 citations

Human epithelial ovarian cancer allelotype.

1993 • 241 citations

Tob, a novel protein that interacts with p185erbB2, is associated with anti-proliferative activity.

1996 • 190 citations

Molecular cloning of PC3, a putatively secreted protein whose mRNA is induced by nerve growth factor and depolarization.

1991 • 185 citations

Structure and expression of TIS21, a primary response gene induced by growth factors and tumor promoters

1991 • 166 citations

Difference of allelotype between squamous cell carcinoma and adenocarcinoma of the lung.

1994 • 161 citations

Frequent allelic losses on chromosomes 2q, 18q, and 22q in advanced non-small cell lung carcinoma.

1994 • 133 citations

Multiple steps in carcinogenesis involving alterations of multiple tumor suppressor genes

1993 • 117 citations

Alterations of the p53 gene are common and critical events for the maintenance of malignant phenotypes in small-cell lung carcinoma.

1992 • 116 citations

Allelotype study of esophageal carcinoma

1994 • 109 citations

A homozygous deletion on chromosome 3 in a small cell lung cancer cell line correlates with a region of tumor suppressor activity

1994 • 108 citations

ANA, a novel member of Tob/BTG1 family, is expressed in the ventricular zone of the developing central nervous system

1998 • 107 citations

Genomic alterations and instabilities in renal cell carcinomas and their relationship to tumor pathology.

1995 • 97 citations

Identification of a novel region of homozygous deletion on chromosome 9p in squamous cell carcinoma of the lung: the location of a putative tumor suppressor gene.

1997 • 92 citations

Overexpression of the nerve growth factor-inducible PC3 immediate early gene is associated with growth inhibition.

1996 • 85 citations

Cytogenetic analysis of 63 non‐small cell lung carcinomas: Recurrent chromosome alterations amid frequent and widespread genomic upheaval

1994 • 84 citations

Genetic changes in epithelial solid neoplasia.

1994 • 84 citations

Comparative allelotype of early and advanced stage non-small cell lung carcinomas

1996 • 81 citations

Homozygous deletions of human chromosome 3p in lung tumors.

1997 • 81 citations

Allelic losses at chromosomes 1p, 2p, 6p, 10p, 13q, 17p, and 21q significantly correlate with the chromophobe subtype of renal cell carcinoma.

1996 • 76 citations

A submicroscopic homozygous deletion at the D3S3 locus in a cell line isolated from a small cell lung carcinoma

1990 • 76 citations

Homozygous deletion at chromosome 2q33 in human small-cell lung carcinoma identified by arbitrarily primed PCR genomic finger printing

1994 • 72 citations

A Notl restriction map of the entire long arm of human chromosome 21

1993 • 72 citations

Isolation and Mapping of Human Chromosome 21 cDNA: Progress in Constructing a Chromosome 21 Expression Map

1994 • 71 citations

Model for a transcript map of human chromosome 21: isolation of new coding sequences from exon and enriched cDNA libraries

1995 • 68 citations

Deletion mapping of chromosome 2 in human lung carcinoma

1996 • 66 citations

Distal nephron renal tumors: microsatellite allelotype.

1996 • 64 citations

Frequent homozygous deletions in lung cancer cell lines detected by a DNA marker located at 3p21.3-p22.

1993 • 63 citations

Base composition and gene distribution: critical patterns in mammalian genome organization

1996 • 62 citations

Commonly deleted regions on the long arm of chromosome 21 in differentiated adenocarcinoma of the stomach

1997 • 52 citations

Commonly deleted regions on the long arm of chromosome 21 in differentiated adenocarcinoma of the stomach

1997 • 49 citations

CDNA selection from 10 Mb of Chromosome 21 DNA: efficiency in transcriptional mapping and reflections of genome organization

1995 • 40 citations

Report of the seventh international workshop on human chromosome 21 mapping 1997

1998 • 38 citations

Report of the Fifth International Workshop on Human Chromosome 21 Mapping 1994

1995 • 30 citations

A Search for Genes from the Dark Band Regions of Human Chromosome 21

1995 • 26 citations