Proviral deletions and oncogene base-substitutions in insertionally mutagenized c-myc alleles may contribute to the progression of avian bursal tumors.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

1981 • 1,611 citations

Nucleotide sequence of rous sarcoma virus

1983 • 901 citations

Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas

1982 • 624 citations

Avian leukosis virus-induced tumors have common proviral integration sites and synthesize discrete new RNAs: oncogenesis by promoter insertion

1981 • 533 citations

Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas

1983 • 504 citations

Gene conversion: Some implications for immunoglobulin genes

1981 • 496 citations

Dilute (d) coat colour mutation of DBA/2J mice is associated with the site of integration of an ecotropic MuLV genome

1981 • 391 citations

Nucleotide sequence of the E. coli gene coding for dihydrofolate reductase

1980 • 378 citations

Analysis of avian leukosis virus DNA and RNA in bursal tumors: Viral gene expression is not required for maintenance of the tumor state

1981 • 346 citations

DNA rearrangements associated with a transposable element in yeast

1980 • 334 citations

Drosophila melanogaster mutations suppressible by the suppressor of Hairy-wing are insertions of a 7.3-kilobase mobile element.

1983 • 302 citations

Isolation and characterization of c-myc, a cellular homolog of the oncogene (v-myc) of avian myelocytomatosis virus strain 29

1982 • 299 citations

Identification and nucleotide sequence of a human locus homologous to the v-myc oncogene of avian myelocytomatosis virus MC29

1983 • 287 citations

Genetic Recombination: Strand Transfer and Mismatch Repair

1978 • 270 citations

Insertion of the eukaryotic transposable element Ty1 creates a 5-base pair duplication

1980 • 266 citations

Retroviruses as mutagens: Insertion and excision of a nontransforming provirus alter expression of a resident transforming provirus

1981 • 253 citations

Translocation joins c-myc and immunoglobulin γ1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene

1983 • 236 citations

Location and function of retroviral and SV40 sequences that enhance biochemical transformation after microinjection of DNA

1983 • 232 citations

Construction of coliphage lambda Charon vectors with BamHI cloning sites

1980 • 230 citations

Molecular cloning and nucleotide sequence of a transforming gene detected by transfection of chicken B-cell lymphoma DNA

1983 • 194 citations

Excision of the DBA ecotropic provirus in dilute coat-color revertants of mice occurs by homologous recombination involving the viral LTRs

1983 • 191 citations

Encapsidation sequences for spleen necrosis virus, an avian retrovirus, are between the 5' long terminal repeat and the start of the gag gene.

1982 • 190 citations

Cloning of human mitochondrial DNA in Escherichia coli

1980 • 189 citations

Nucleotide sequence analysis of the chicken c-myc gene reveals homologous and unique coding regions by comparison with the transforming gene of avian myelocytomatosis virus MC29, delta gag-myc.

1983 • 187 citations

Nucleotide sequence to the v-myc oncogene of avian retrovirus MC29.

1983 • 184 citations

Nucleotide sequence analysis of the Long Terminal Repeat (LTR) of avian retroviruses: Structural similarities with transposable elements

1980 • 173 citations

Analysis of the defectiveness of rous sarcoma virus III. Determining influence of a new helper virus on the host range and susceptibility to interference of RSV

1965 • 151 citations

Specific integration of REV proviruses in avian bursal lymphomas

1981 • 138 citations

Nucleotide sequence of cloned unintegrated avian sarcoma virus DNA: viral DNA contains direct and inverted repeats similar to those in transposable elements.

1981 • 130 citations

On the mechanism of retrovirus-induced avian lymphoid leukosis: deletion and integration of the proviruses.

1981 • 129 citations

Avian oncovirus mutant (SE21Q1b) deficient in genomic RNA: characterization of a deletion in the provirus

1980 • 127 citations

Intergenic conversion and reiterated genes

1981 • 100 citations

DNA clones containing mouse immunoglobulin kappa chain genes isolated by in vitro packaging into phage lambda coats.

1978 • 98 citations

A heterogeneity of rous sarcoma virus revealed by selectively resistant chick embryo cells

1965 • 85 citations

Identification of a sequence likely to be required for avian retroviral packaging

1983 • 75 citations

The leader sequence of the subgenomic mRNA's of Rous sarcoma virus is approximately 390 nucleotides

1982 • 74 citations

Insertion of a movable genetic element, 297, into the T-A-T-A box for the H3 histone gene in Drosophila melanogaster.

1982 • 74 citations

Molecular analysis of the c-myc locus in normal tissue and in avian leukosis virus-induced lymphomas

1982 • 69 citations

Close relationship between the long terminal repeats of avian leukosis-sarcoma virus and copia-like movable genetic elements of Drosophila.

1983 • 66 citations

Expression of c-myc RNA in bursal lymphoma cell lines: Identification of c-myc-encoded proteins by hybrid-selected translation

1983 • 44 citations