Tyrosine kinase‐dependent activation of human NK cell functions upon triggering through CD44 receptor

Biology of Natural Killer Cells

1989 • 2,970 citations

CD44 and Its Interaction with Extracellular Matrix

1993 • 1,082 citations

The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells

1994 • 457 citations

Interaction of Fc receptor (CD16) ligands induces transcription of interleukin 2 receptor (CD25) and lymphokine genes and expression of their products in human natural killer cells.

1988 • 373 citations

Dual role of the CD44 molecule in T cell adhesion and activation.

1989 • 335 citations

LFA-3, CD44, and CD45: Physiologic Triggers of Human Monocyte TNF and IL-1 Release

1990 • 300 citations

Interleukin 2 activation of natural killer cells rapidly induces the expression and phosphorylation of the Leu-23 activation antigen.

1988 • 244 citations

Antibodies against the CD44 p80, lymphocyte homing receptor molecule augment human peripheral blood T cell activation.

1990 • 230 citations

CD69-mediated pathway of lymphocyte activation: anti-CD69 monoclonal antibodies trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing T cell receptor alpha/beta.

1991 • 219 citations

[31] Use and selectivity of herbimycin A as inhibitor of protein-tyrosine kinases

1991 • 218 citations

Signaling through CD44 Is Mediated by Tyrosine Kinases

1996 • 189 citations

Fc gamma receptor activation induces the tyrosine phosphorylation of both phospholipase C (PLC)-gamma 1 and PLC-gamma 2 in natural killer cells.

1992 • 138 citations

NKR-P1, an activating molecule on rat natural killer cells, stimulates phosphoinositide turnover and a rise in intracellular calcium.

1991 • 124 citations

Expression and function of CD7 molecule on human natural killer cells.

1994 • 121 citations

Stimulation of Fc gamma RIIIA results in phospholipase C-gamma 1 tyrosine phosphorylation and p56lck activation.

1992 • 108 citations

Engagement of the natural killer cell IgG Fc receptor results in tyrosine phosphorylation of the zeta chain.

1991 • 102 citations

Tyrosine phosphorylation provides an early and requisite signal for the activation of natural killer cell cytotoxic function.

1991 • 93 citations

Antibodies to CD44 trigger effector functions of human T cell clones.

1993 • 87 citations

Regulation of CD69 expression on human natural killer cells: differential involvement of protein kinase C and protein tyrosine kinases

1993 • 79 citations

CD44 triggering enhances human NK cell cytotoxic functions.

1994 • 75 citations

A role for protein tyrosine kinase activity in natural cytotoxicity as well as antibody-dependent cellular cytotoxicity. Effects of herbimycin A.

1992 • 64 citations

CD44 is a cytotoxic triggering molecule in human peripheral blood NK cells.

1994 • 62 citations

Tyrosine kinase-dependent activation of human NK cell functions upon stimulation through a 58-kDa surface antigen selectively expressed on discrete subsets of NK cells and T lymphocytes.

1994 • 61 citations

CD16-mediated p21ras activation is associated with Shc and p36 tyrosine phosphorylation and their binding with Grb2 in human natural killer cells.

1996 • 53 citations

Protein tyrosine phosphorylation and p56lck modification in IL-2 or phorbol ester-activated human natural killer cells.

1990 • 52 citations

Expression of vitronectin receptor on human NK cells and its role in protein phosphorylation, cytokine production, and cell proliferation.

1995 • 43 citations

Downregulation of Fcγ Receptor IIIAα (CD16-II) on Natural Killer Cells Induced by Anti-CD16 mAb Is Independent of Protein Tyrosine Kinases and Protein Kinase C

1994 • 41 citations

Long term activation of natural killer cells results in modulation of beta 1-integrin expression and function.

1994 • 34 citations

8. The role of plant growth regulators in dormancy in forest trees

1987 • 31 citations

Stimulation of protein tyrosine phosphorylation by interaction of NK cells with fibronectin via alpha 4 beta 1 and alpha 5 beta 1.

1995 • 27 citations

The CD26 Antigen is Coupled to Protein Tyrosine Phosphorylation and Implicated in CD16‐Mediated Lysis in Natural Killer Cells

1993 • 22 citations