Structural and functional characterization of the .alpha.5 segment of Bacillus thuringiensis .delta.-endotoxin

Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor.

1987 • 2,216 citations

Determination of the helix and β form of proteins in aqueous solution by circular dichroism

1974 • 2,040 citations

Mechanism by which cyanine dyes measure membrane potential in red blood cells and phosphatidylcholine vesicles

1974 • 949 citations

The Mode of Action of Bacillus Thuringiensis Endotoxins

1992 • 783 citations

Crystal structure of insecticidal δ-endotoxin from Bacillus thuringiensis at 2.5 Å resolution

1991 • 747 citations

Parallax method for direct measurement of membrane penetration depth utilizing fluorescence quenching by spin-labeled phospholipids

1987 • 671 citations

Interaction of antimicrobial dermaseptin and its fluorescently labeled analogs with phospholipid membranes

1992 • 646 citations

Synthetic Amphiphilic Peptide Models for Protein Ion Channels

1988 • 593 citations

Phospholipid model membranes. I. Structural characteristics of hydrated liquid crystals

1967 • 589 citations

Molecular model of the action potential sodium channel.

1986 • 525 citations

Colloid-osmotic lysis is a general feature of the mechanism of action of Bacillus thuringiensis δ-endotoxins with different insect specificity

1987 • 448 citations

Mechanism of Insect Resistance to the Microbial Insecticide Bacillus thuringiensis

1990 • 353 citations

Synthesis of the antibacterial peptide cecropin A(1-33)

1982 • 330 citations

Isolation, amino acid sequence and synthesis of dermaseptin, a novel antimicrobial peptide of amphibian skin

1991 • 305 citations

Melittin binding to mixed phosphatidylglycerol/phosphatidylcholine membranes

1990 • 291 citations

Ordered conformation of polypeptides and proteins in acidic dodecyl sulfate solution

1981 • 226 citations

The Molecular Biology of Parasporal Crystal Body Formation in Bacillus Thuringiensis

1986 • 213 citations

Interaction of fluorescently labeled pardaxin and its analogues with lipid bilayers.

1991 • 201 citations

Differential light scattering and absorption flattening optical effects are minimal in the circular dichroism spectra of small unilamellar vesicles

1984 • 196 citations

The structure of the voltage‐sensitive sodium channel

1985 • 193 citations

Channel formation properties of synthetic pardaxin and analogues

1990 • 180 citations

Incorporation of Melittin into phosphatidylcholine bilayers

1981 • 178 citations

Thermodynamic analysis of incorporation and aggregation in a membrane: Application to the pore-forming peptide alamethicin

1986 • 166 citations

Alamethicin incorporation in lipid bilayers: a thermodynamic study

1987 • 166 citations

Delta-endotoxins form cation-selective channels in planar lipid bilayers

1990 • 147 citations

Novel peptide fragments originating from PGLa and the caerulein and xenopsin precursors from Xenopus laevis.

1986 • 144 citations

Bacillus thuringiensis toxin inhibits K⁺‐gradient‐dependent amino acid transport across the brush border membrane of Pieris brassicae midgut cells

1986 • 133 citations

Localized mutagenesis defines regions of the Bacillus thuringiensis delta-endotoxin involved in toxicity and specificity.

1992 • 131 citations

M2 delta, a candidate for the structure lining the ionic channel of the nicotinic cholinergic receptor.

1988 • 130 citations

Channel protein engineering: synthetic 22-mer peptide from the primary structure of the voltage-sensitive sodium channel forms ionic channels in lipid bilayers.

1988 • 126 citations

Incorporation kinetics in a membrane, studied with the pore-forming peptide alamethicin

1987 • 120 citations

Synthesis, location, and lateral mobility of fluorescently labeled ubiquinone 10 in mitochondrial and artificial membranes

1989 • 118 citations

A Three-Dimensional Molecular Assembly Model of a Lipoprotein from the Escherichia coli Outer Membrane

1974 • 117 citations

New fluorescent probe for protein and nucleoprotein conformation. Binding of 7-(p-methoxybenzylamino)-4-nitrobenzoxadiazole to bovine trypsinogen and bacterial ribosomes

1971 • 107 citations

Aggregation and organization of pardaxin in phospholipid membranes. A fluorescence energy transfer study.

1992 • 103 citations

Membrane insertion and lateral diffusion of fluorescence-labelled cytochrome c oxidase subunit IV signal peptide in charged and uncharged phospholipid bilayers

1990 • 95 citations

Electrostatics of a peptide at a membrane/water interface. The pH dependence of melittin association with lipid vesicles

1990 • 84 citations

The amphiphilic α‐helix concept

1991 • 82 citations

Solid‐phase synthesis of PYL^a and isolation of its natural counterpart, PGL^a [PYL^a‐(4–24)] from skin secretion of Xenopus laevis

1985 • 82 citations

Interaction of D-amino acid incorporated analogs of pardaxin with membranes

1992 • 77 citations

Voltage-gated channels formed in lipid bilayers by a positively charged segment of the Na-channel polypeptide.

1989 • 70 citations

Diffusion potential cascade. Convenient detection of transferable membrane pores

1983 • 69 citations

Mechanism of action of Bacillus thuringiensis insecticidal δ-endotoxin: interaction with phospholipid vesicles

1989 • 58 citations

pH-dependent pore formation properties of pardaxin analogues.

1991 • 57 citations

Ion channel formation by synthetic transmembrane segments of the inhibitory glycine receptor — a model study

1991 • 53 citations

Directed mutagenesis of selected regions of abacillus thuringiensisentomocidal protein

1990 • 51 citations

Neither barium nor calcium prevents the inhibition by Bacillus thuringiensis δ‐endotoxin of sodium‐ or potassium gradient‐dependent amino acid accumulation by tobacco hornworm midgut brush border membrane vesicles

1989 • 36 citations

Ion channels formed by a highly charged peptide

1991 • 26 citations

Membrane interactions of the sodium channel S4 segment and its fluorescently-labeled analogs

1992 • 25 citations

Fluorescence and carbon-13 NMR determination of side-chain and backbone dynamics of synthetic melittin and melittin analogs in isotropic solvents

1989 • 19 citations

Interaction between the δ‐endotoxin produced by Bacillus thuringiensis ssp. entomocidus and liposomes

1988 • 19 citations

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