Infection and autoimmunity

Hay fever, hygiene, and household size.

1989 • 4,910 citations

Family size, infection and atopy: the first decade of the 'hygiene hypothesis'

2000 • 1,173 citations

The internal secretion of the pancreas

1922 • 800 citations

Trichuris suis therapy for active ulcerative colitis: A randomized controlled trial

2005 • 717 citations

Infection, immune responses and the aetiology of childhood leukaemia

2006 • 613 citations

The Murine Autoimmune Diabetes Model: NOD and Related Strains

1992 • 498 citations

Association between parasite infection and immune responses in multiple sclerosis

2007 • 454 citations

Trichuris suis seems to be safe and possibly effective in the treatment of inflammatory bowel disease

2003 • 413 citations

Genetic Liability of Type 1 Diabetes and the Onset Age Among 22,650 Young Finnish Twin Pairs

2003 • 384 citations

Human intestinal parasites in the past: new findings and a review

2003 • 316 citations

Schistosoma mansoni antigens modulate the activity of the innate immune response and prevent onset of type 1 diabetes

2003 • 312 citations

Infection with Schistosoma mansoni prevents insulin dependent diabetes mellitus in non‐obese diabetic mice

1999 • 309 citations

Exposure to schistosome eggs protects mice from TNBS-induced colitis

2003 • 283 citations

Heligmosomoides polygyrus inhibits established colitis in IL‐10‐deficient mice

2004 • 278 citations

Intestinal Nematode Infection Ameliorates Experimental Colitis in Mice

2002 • 264 citations

Toll-Like Receptor 4-Mediated Innate IL-10 Activates Antigen-Specific Regulatory T Cells and Confers Resistance toBordetella pertussisby Inhibiting Inflammatory Pathology

2003 • 263 citations

Schistosomiasis Decreases Central Nervous System Inflammation and Alters the Progression of Experimental Autoimmune Encephalomyelitis

2003 • 260 citations

Immunomodulation of experimental autoimmune encephalomyelitis by helminth ova immunization

2002 • 248 citations

A worm's eye view of the immune system: consequences for evolution of human autoimmune disease

2005 • 241 citations

Inhibition of Autoimmune Type 1 Diabetes by Gastrointestinal Helminth Infection

2006 • 223 citations

A Novel Therapeutic Approach Targeting Articular Inflammation Using the Filarial Nematode-Derived Phosphorylcholine-Containing Glycoprotein ES-62

2003 • 202 citations

Regulation of allergy and autoimmunity in helminth infection

2004 • 158 citations

Schistosoma mansoni and α-Galactosylceramide: Prophylactic Effect of Th1 Immune Suppression in a Mouse Model of Graves’ Hyperthyroidism

2004 • 101 citations

Trichuris trichiura eggs in the neolithic glacier mummy from the Alps

1996 • 85 citations

Diabetes‐prone NOD mice are resistant to Mycobacterium avium and the infection prevents autoimmune disease

1996 • 73 citations

Original article: Infections presenting for clinical care in early life and later risk of hay fever in two UK birth cohorts

2008 • 58 citations

Salmonella typhimurium infection halts development of type 1 diabetes in NOD mice

2004 • 48 citations

Murine Gammaherpesvirus-68 Infection Alters Self-Antigen Presentation and Type 1 Diabetes Onset in NOD Mice

2007 • 40 citations

Salmonella typhimurium Infection in Nonobese Diabetic Mice Generates Immunomodulatory Dendritic Cells Able to Prevent Type 1 Diabetes

2006 • 37 citations

Mycobacteria Precipitate Autoimmune Rheumatic Disease in NOD Mice Via an Adjuvant‐Like Activity

1994 • 29 citations

Prevention of experimental colitis by parenteral administration of a pathogen-derived immunomodulatory molecule

2006 • 26 citations

Streptococcus sanguisModulates Type II Collagen-Induced Arthritis in DBA/1J Mice

2002 • 15 citations

Can helminth antigens be exploited therapeutically to downregulate pathological Th1 responses?

2004 • 10 citations

Regulatory cells and the control of respiratory infection

2005 • 9 citations