Absence of Cardiolipin Results in Temperature Sensitivity, Respiratory Defects, and Mitochondrial DNA Instability Independent of pet56

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

The biosynthesis and functional role of cardiolipin

2000 • 786 citations

Cardiolipin Stabilizes Respiratory Chain Supercomplexes

2003 • 783 citations

Replacement of chromosome segments with altered DNA sequences constructed in vitro.

1979 • 779 citations

A novel X-linked gene, G4.5. is responsible for Barth syndrome

1996 • 733 citations

An X-linked mitochondrial disease affecting cardiac muscle, skeletal muscle and neutrophil leucocytes

1983 • 662 citations

Absence of Cardiolipin in the crd1 Null Mutant Results in Decreased Mitochondrial Membrane Potential and Reduced Mitochondrial Function

2000 • 409 citations

Defective Remodeling of Cardiolipin and Phosphatidylglycerol in Barth Syndrome

2000 • 369 citations

Roles of Phosphatidylethanolamine and of Its Several Biosynthetic Pathways inSaccharomyces cerevisiae

2001 • 266 citations

Phosphatidylserine decarboxylase from Saccharomyces cerevisiae. Isolation of mutants, cloning of the gene, and creation of a null allele.

1993 • 226 citations

Isolation and Characterization of the Gene (CLS1 ) Encoding Cardiolipin Synthase in Saccharomyces cerevisiae

1998 • 212 citations

Yeast mutant defective in phosphatidylserine synthesis.

1980 • 207 citations

Aberrant cardiolipin metabolism in the yeast taz1 mutant: a model for Barth syndrome

2003 • 192 citations

Cardiolipin is not essential for the growth of Saccharomyces cerevisiae on fermentable or non‐fermentable carbon sources

1997 • 182 citations

Polymorphic regulation of membrane phospholipid composition in Escherichia coli

1993 • 156 citations

YDL142c encodes cardiolipin synthase (Cls1p) and is non-essential for aerobic growth ofSaccharomyces cerevisiae

1998 • 151 citations

Cardiolipin prevents rate-dependent uncoupling and provides osmotic stability in yeast mitochondria

2002 • 139 citations

Functional Requirement of a Site-Specific Ribose Methylation in Ribosomal RNA

1993 • 129 citations

Oxidative phosphorylation in cardiolipin-lacking yeast mitochondria

2000 • 126 citations

Mutation analysis of the G4.5 gene in patients with isolated left ventricular noncompaction

2002 • 124 citations

Thin-layer chromatography of human platelet phospholipids with fatty acid analysis

1987 • 114 citations

Isolation of a Chinese Hamster Ovary (CHO) cDNA Encoding Phosphatidylglycerophosphate (PGP) Synthase, Expression of Which Corrects the Mitochondrial Abnormalities of a PGP Synthase-defective Mutant of CHO-K1 Cells

1999 • 97 citations

X‐linked cardioskeletal myopathy and neutropenia (Barth syndrome): Respiratory‐chain abnormalities in cultured fibroblasts

1996 • 96 citations

CARDIOLIPIN CONTENT OF WILD TYPE AND MUTANT YEASTS IN RELATION TO MITOCHONDRIAL FUNCTION AND DEVELOPMENT

1971 • 95 citations

Cardiolipin synthase expression is essential for growth at elevated temperature and is regulated by factors affecting mitochondrial development

1999 • 62 citations

Large-scale phenotypic analysis—the pilot project on yeast chromosome III

1997 • 58 citations

Carbon Source Regulation of PIS1 Gene Expression in Saccharomyces cerevisiae Involves the MCM1 Gene and the Two-component Regulatory Gene, SLN1

1996 • 45 citations

Regulation of phosphatidylglycerolphosphate synthase in Saccharomyces cerevisiae by factors affecting mitochondrial development

1991 • 42 citations

Cardiolipin Is Not Required to Maintain Mitochondrial DNA Stability or Cell Viability for Saccharomyces cerevisiae Grown at Elevated Temperatures

2003 • 37 citations

A genetic screen for ethanolamine auxotrophs in Saccharomyces cerevisiae identifies a novel mutation in Mcd4p, a protein implicated in glycosylphosphatidylinositol anchor synthesis

2001 • 22 citations