Examination of two genetic polymorphisms within the renin-angiotensin system: no evidence for an association with nephropathy in IDDM

An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

1990 • 3,809 citations

Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction

1992 • 1,956 citations

Molecular basis of human hypertension: Role of angiotensinogen

1992 • 1,861 citations

PCR detection of the insertion/deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1)

1992 • 1,280 citations

Diabetic nephropathy in type 1 (insulin-dependent) diabetes: An epidemiological study

1983 • 1,078 citations

Familial Clustering of Diabetic Kidney Disease

1989 • 991 citations

The changing natural history of nephropathy in type I Diabetes

1985 • 792 citations

Association between a Deletion Polymorphism of the Angiotensin-Converting-Enzyme Gene and Left Ventricular Hypertrophy

1994 • 757 citations

Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats

1991 • 614 citations

The effect of proteinuria on relative mortality in Type 1 (insulin-dependent) diabetes mellitus

1985 • 611 citations

Mistyping ACE heterozygotes.

1993 • 522 citations

Renal protective effect of enalapril in diabetic nephropathy.

1992 • 437 citations

Angiotensin-converting enzyme DD genotype in patients with ischaemic or idiopathic dilated cardiomyopathy

1993 • 426 citations

Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death

1993 • 412 citations

Relationships Between Angiotensin I Converting Enzyme Gene Polymorphism, Plasma Levels, and Diabetic Retinal and Renal Complications

1994 • 361 citations

Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease

1995 • 310 citations

Raised arterial pressure in parents of proteinuric insulin dependent diabetics.

1987 • 308 citations

Is diabetic nephropathy an inherited complication?

1992 • 303 citations

Relation between blood pressure and renin, renin substrate, angiotensin II, aldosterone and urinary sodium and potassium in 574 ambulatory subjects.

1979 • 289 citations

Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is strongly associated with coronary heart disease in non-insulin-dependent diabetes mellitus.

1994 • 236 citations

Polymorphisms in angiotensin-converting-enzyme gene and progression of IgA nephropathy

1995 • 214 citations

Rapid detection of the hypertension-associated Met²³⁵→ Thr allele of the human angiotensinogen gene

1993 • 208 citations

Lack of Relationship Between an Insertion/Deletion Polymorphism in the Angiotensin I–Converting Enzyme Gene and Diabetic Nephropathy and Proliferative Retinopathy in IDDM Patients

1995 • 187 citations

Genetic Predisposition to Diabetic Nephropathy: Evidence for a Role of the Angiotensin I–Converting Enzyme Gene

1994 • 185 citations

Association of ACE gene polymorphism and diabetic nephropathy?

1995 • 180 citations

Association between angiotensin-converting-enzyme gene polymorphism and failure of renoprotective therapy

1996 • 170 citations

Predictive value of microalbuminuria in patients with insulin-dependent diabetes of long duration.

1992 • 162 citations

Pregnancies in women with diabetic nephropathy: long-term outcome for mother and child

1995 • 102 citations

Sodium-lithium countertransport activity in red cells of patients with insulin dependent diabetes and nephropathy and their parents.

1990 • 88 citations

Insertion/deletion polymorphism in the angiotensin-l-converting enzyme gene is associated with coronary heart disease in IDDM patients with diabetic nephropathy

1995 • 86 citations

Disease Associations: Chance, Artifact, or Susceptibility Genes?

1989 • 82 citations

Increased prevalence of renal biopsy findings other than diabetic glomerulopathy in type II diabetes mellitus

1992 • 81 citations

Elevated serum angiotensin I converting enzyme activity in type I, insulin-dependent diabetic subjects with persistent microalbuminuria

1992 • 39 citations

Deleted Work

1955 • 0 citations