The budding yeast U5 snRNP Prp8 is a highly conserved protein which links RNA splicing with cell cycle progression

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Getting started with yeast

2002 • 3,496 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

[1] Getting started with yeast

1991 • 2,456 citations

Separation of Large DNA Molecules by Contour-Clamped Homogeneous Electric Fields

1986 • 1,525 citations

Saccharomyces cerevisiae cell cycle

1974 • 747 citations

Transcriptional Activation Modulated by Homopolymeric Glutamine and Proline Stretches

1994 • 598 citations

Nuclear protein localization

1991 • 570 citations

RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis

1986 • 524 citations

CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae.

1993 • 521 citations

The C. elegans genome sequencing project: a beginning

1992 • 496 citations

Messenger RNA Splicing in Yeast: Clues to Why the Spliceosome Is a Ribonucleoprotein

1991 • 433 citations

CLB5: a novel B cyclin from budding yeast with a role in S phase.

1992 • 391 citations

Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae.

1989 • 340 citations

A group of interacting yeast DNA replication genes.

1991 • 325 citations

3,400 new expressed sequence tags identify diversity of transcripts in human brain

1993 • 292 citations

Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2.

1992 • 281 citations

Interaction of Dbf4, the Cdc7 Protein Kinase Regulatory Subunit, with Yeast Replication Origins in Vivo

1994 • 213 citations

Identification of ten genes that control ribosome formation in yeast

1970 • 182 citations

Identification of a yeast snRNP protein and detection of snRNP-snRNP interactions

1987 • 180 citations

Diverse Essential Functions Revealed by Complementing Yeast Calmodulin Mutants

1994 • 142 citations

The yeast RNA gene products are essential for mRNA splicing in vitro

1986 • 138 citations

THE TIMING OF DEOXYRIBONUCLEIC ACID SYNTHESIS IN THE CELL CYCLE OF SACCHAROMYCES CEREVISIAE

1965 • 134 citations

The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition.

1994 • 130 citations

Heat shock proteins affect RNA processing during the heat shock response of Saccharomyces cerevisiae.

1991 • 127 citations

The product of the Saccharomyces cerevisiae cell cycle gene DBF2 has homology with protein kinases and is periodically expressed in the cell cycle.

1990 • 124 citations

Heat Shock-Mediated Cell Cycle Blockage and G1 Cyclin Expression in the Yeast Saccharomyces cerevisiae

1993 • 119 citations

Temperature-sensitive cdc7 mutations of Saccharomyces cerevisiae are suppressed by the DBF4 gene, which is required for the G1/S cell cycle transition.

1992 • 103 citations

A new pair of B-type cyclins from Saccharomyces cerevisiae that function early in the cell cycle.

1993 • 95 citations

Roles of PRP8 protein in the assembly of splicing complexes.

1992 • 91 citations

The Spliceosome

1993 • 80 citations

The isolation of new DNA synthesis mutants in the yeastSaccharomyces cerevisiae

1982 • 79 citations

A further two mutants defective in initiation of the S phase in the yeastSaccharomyces cerevisiae

1982 • 79 citations

The mammalian analogue of the yeast PRP8 splicing protein is present in the U4/5/6 small nuclear ribonucleoprotein particle and the spliceosome.

1989 • 74 citations

Role of Protein Synthesis in the Replication of Yeast DNA

1973 • 64 citations

New temperature-sensitive mutants of Saccharomyces cerevisiae affecting DNA replication

1982 • 61 citations

Affinity purification of spliceosomes reveals that the precursor RNA processing protein PRP8, a protein in the U5 small nuclear ribonucleoprotein particle, is a component of yeast spliceosomes.

1990 • 59 citations

Protein Synthesis Requirements for Nuclear Division, Cytokinesis, and Cell Separation in Saccharomyces cerevisiae

1991 • 56 citations

A mammalian protein of 220 kDa binds pre-mRNAs in the spliceosome: a potential homologue of the yeast PRP8 protein.

1990 • 55 citations

SRN1, a yeast gene involved in RNA processing, is identical to HEX2/REG1, a negative regulator in glucose repression.

1992 • 41 citations

SPO12andSIT4suppress mutations inDBF2, which encodes a cell cycle protein kinase that is periodically expressed

1992 • 39 citations

The yeast PRP8 protein intersacts directly with pre-mRNA

1991 • 37 citations

The Product of the Saccharomyces cerevisiae Cell Cycle Gene DBF2 Has Homology with Protein Kinases and Is Periodically Expressed in the Cell Cycle

1990 • 35 citations

Small nuclear RNAs and pre-mRNA splicing

1994 • 31 citations

Heat Shock Proteins Affect RNA Processing during the Heat Shock Response of Saccharomyces cerevisiae

1991 • 28 citations

Rapid mapping by transposon mutagenesis of epitopes on the muscular dystrophy protein, dystrophin

1991 • 26 citations

A suppressor of temperature-sensitive rna mutations that affect mRNA metabolism in Saccharomyces cerevisiae.

1982 • 23 citations

TheSSB1heat shock cognate gene of the yeastSaccharomyces cerevisiae

1989 • 20 citations

SRN1, a Yeast Gene Involved in RNA Processing, Is Identical to HEX2/REG1, a Negative Regulator in Glucose Repression

1992 • 16 citations

Cloning and nucleotide sequence of the CDC23 gene of Saccharomyces cerevisiae

1990 • 8 citations

A Suppressor of Temperature-Sensitive rna Mutations that Affect mRNA Metabolism in Saccharomyces cerevisiae

1982 • 8 citations