Affinity purification of spliceosomes reveals that the precursor RNA processing protein PRP8, a protein in the U5 small nuclear ribonucleoprotein particle, is a component of yeast spliceosomes.

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes

1987 • 530 citations

SPLICEOSOMAL snRNAs

1988 • 463 citations

[9] Specific labeling of 3′ termini of RNA with T4 RNA ligase

1980 • 421 citations

Spliceosome assembly in yeast.

1987 • 402 citations

A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability.

1987 • 401 citations

A single gene from yeast for both nuclear and cytoplasmic polyadenylate-binding proteins: Domain structure and expression

1986 • 389 citations

Yeast mRNA splicing in vitro.

1985 • 337 citations

An Early Hierarchic Role of U1 Small Nuclear Ribonucleoprotein in Spliceosome Assembly

1988 • 271 citations

Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome.

1986 • 215 citations

Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles.

1988 • 183 citations

Identification of ten genes that control ribosome formation in yeast

1970 • 182 citations

Identification of a yeast snRNP protein and detection of snRNP-snRNP interactions

1987 • 180 citations

A Single Domain of Yeast Poly(A)-Binding Protein Is Necessary and Sufficient for RNA Binding and Cell Viability

1987 • 158 citations

The yeast RNA gene products are essential for mRNA splicing in vitro

1986 • 138 citations

Specific small nuclear RNAs are associated with yeast spliceosomes

1986 • 127 citations

RNA11 protein is associated with the yeast spliceosome and is localized in the periphery of the cell nucleus.

1988 • 102 citations

Conservation between yeast and man of a protein associated with U5 small nuclear ribonucleoprotein

1989 • 101 citations

Gel Electrophoretic Isolation of Splicing Complexes Containing U1 Small Nuclear Ribonucleoprotein Particles

1988 • 95 citations

The mammalian analogue of the yeast PRP8 splicing protein is present in the U4/5/6 small nuclear ribonucleoprotein particle and the spliceosome.

1989 • 74 citations

Cloning of the RNA8 gene of Saccharomyces cerevisiae, detection of the RNA8 protein, and demonstration that it is essential for nuclear pre-mRNA splicing.

1988 • 72 citations

RNA11 Protein is Associated with the Yeast Spliceosome and is Localized in the Periphery of the Cell Nucleus

1988 • 45 citations

Cloning of the RNA8 Gene of Saccharomyces cerevisiae, Detection of the RNA8 Protein, and Demonstration that It Is Essential for Nuclear Pre-mRNA Splicing

1988 • 28 citations