Role of the Nude Gene in Epithelial Terminal Differentiation

Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor

1999 • 6,443 citations

Mammalian MAP kinase signalling cascades

2001 • 5,041 citations

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

1995 • 3,456 citations

The MAPK signaling cascade

1995 • 3,300 citations

Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

1998 • 3,026 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

Calcium regulation of growth and differentiation of mouse epidermal cells in culture

1980 • 1,810 citations

Unified nomenclature for the winged helix/forkhead transcription factors

2000 • 1,136 citations

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

1999 • 1,102 citations

Direct control of the Forkhead transcription factor AFX by protein kinase B

1999 • 1,080 citations

The secret life of the hair follicle

1992 • 919 citations

‘Nude’, a new hairless gene with pleiotropic effects in the mouse

1966 • 834 citations

Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: Activation of the cross-linking by calcium ions

1979 • 792 citations

Five years on the wings of fork head

1996 • 657 citations

New member of the winged-helix protein family disrupted in mouse and rat nude mutations

1994 • 651 citations

Acid and base hydrolysis of phosphoproteins bound to Immobilon facilitates analysis of phosphoamino acids in gel-fractionated proteins

1989 • 469 citations

Two Genetically Separable Steps in the Differentiation of Thymic Epithelium

1996 • 447 citations

Calcium regulation of cell-cell contact and differentiation of epidermal cells in culture *1An ultrastructural study

1983 • 370 citations

Signaling via β1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro

1999 • 246 citations

Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins

1987 • 187 citations

The Epidermis: Genes On – Genes Off

1997 • 181 citations

Diverse Mitogenic Agents Induce the Phosphorylation of Two Related 42,000-Dalton Proteins on Tyrosine in Quiescent Chick Cells

1984 • 159 citations

The product of the mouse nude locus, Whn, regulates the balance between epithelial cell growth and differentiation.

1996 • 149 citations

Tissue- and stratum-specific expression of the human involucrin promoter in transgenic mice.

1993 • 141 citations

Positional Cloning of the nude Locus: Genetic, Physical, and Transcription Maps of the Region and Mutations in the Mouse and Rat

1995 • 130 citations

Association between MousenudeGene Expression and the Initiation of Epithelial Terminal Differentiation

1999 • 125 citations

fyn tyrosine kinase is involved in keratinocyte differentiation control.

1995 • 113 citations

Epidermal differentiation

1990 • 101 citations

The nude gene encodes a sequence-specific DNA binding protein with homologs in organisms that lack an anticipatory immune system

1997 • 101 citations

The whn transcription factor encoded by the nude locus contains an evolutionarily conserved and functionally indispensable activation domain.

1996 • 92 citations

Diverse mitogenic agents induce the phosphorylation of two related 42,000-dalton proteins on tyrosine in quiescent chick cells.

1984 • 90 citations

Characterization of mouse and human nude genes

1997 • 85 citations

Identification of Proteolytic Cleavage Sites in the Conversion of Profilaggrin to Filaggrin in Mammalian Epidermis

1989 • 80 citations

Ectopic Expression of the nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia

1999 • 74 citations

Forkhead/winged-helix transcription factor whn regulates hair keratin gene expression: Molecular analysis of theNude skin phenotype

2000 • 74 citations

Nude Mice Are Not Hairless

1990 • 72 citations

Athymic Development in the Mouse

1973 • 69 citations

Involucrin, a marker of squamous and urothelial differentiation. An immunohistochemical study on its distribution in normal and neoplastic tissues

1985 • 68 citations

Domina (Dom), a new Drosophila member of the FKH/WH gene family, affects morphogenesis and is a suppressor of position-effect variegation

2000 • 36 citations

Calcium Inhibits Epidermal Growth Factor-Induced Activation of p21^ras in Human Primary Keratinocytes

1994 • 35 citations

Involucrin mRNA Is More Abundant in Human Hair Follicles Than in Normal Epidermis

1994 • 35 citations

Genetically separable determinants of hair keratin gene expression

2000 • 27 citations

Calcium inhibits epidermal growth factor-induced activation of p21ras in human primary keratinocytes.

1994 • 21 citations

A Drosophila Winged‐helix nude (Whn)‐like transcription factor with essential functions throughout development

2000 • 12 citations