Scleroderma: A disease related to damaged proteins?

Endoglin, a TGF-β binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1

1994 • 1,452 citations

Determinant spreading and the dynamics of the autoimmune T-cell repertoire

1993 • 467 citations

The Textbook of Rheumatology.

1997 • 454 citations

DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis.

1995 • 422 citations

How can cryptic epitopes trigger autoimmunity?

1995 • 254 citations

IgG antiendothelial cell autoantibodies from scleroderma patients induce leukocyte adhesion to human vascular endothelial cells in vitro. Induction of adhesion molecule expression and involvement of endothelium-derived cytokines.

1996 • 219 citations

Scleroderma Autoantigens Are Uniquely Fragmented by Metal-catalyzed Oxidation Reactions: Implications for Pathogenesis

1997 • 210 citations

Modulation of transforming growth factor beta receptor levels on microvascular endothelial cells during in vitro angiogenesis.

1996 • 161 citations

Analysis of the autoantibody response to fibrillarin in human disease and murine models of autoimmunity.

1995 • 98 citations

Increased susceptibility to oxidation of low‐density lipoproteins isolated from patients with systemic sclerosis

1995 • 92 citations

T and B cell collaboration is essential for the autoantibody response to DNA topoisomerase I in systemic sclerosis.

1995 • 67 citations

Raynaud??s phenomenon and other features of scleroderma, including pulmonary hypertension

1996 • 22 citations