Mechanism of E1A-Induced Transforming Growth Factor-β (TGF-β) Resistance in Mouse Keratinocytes Involves Repression of TGF-β Type II Receptor Transcription

TGFβ signals through a heteromeric protein kinase receptor complex

1992 • 1,519 citations

Autocrine growth factors and cancer

1985 • 1,462 citations

Peptide Growth Factors and Their Receptors

1991 • 1,221 citations

TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights

1990 • 992 citations

Cellular targets for transformation by the adenovirus E1A proteins

1989 • 747 citations

Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B

1990 • 730 citations

Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1.

1992 • 675 citations

The Quest for Human Cancer Viruses

1962 • 540 citations

A transforming growth factor beta receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability.

1995 • 445 citations

Genetic changes in the transforming growth factor beta (TGF-beta) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-beta.

1994 • 431 citations

Characterization of the Promoter Region of the Human Transforming Growth Factor-β1 Gene

1989 • 400 citations

Transforming growth factor beta and cell cycle regulation.

1995 • 368 citations

Absence of TGF-β Receptors and Growth Inhibitory Responses in Retinoblastoma Cells

1988 • 331 citations

Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells

1994 • 325 citations

Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction.

1990 • 319 citations

A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells

1989 • 262 citations

Responsiveness to transforming growth factor-beta (TGF-beta) restored by genetic complementation between cells defective in TGF-beta receptors I and II

1991 • 252 citations

Sequence requirements for premature termination of transcription in the human c-myc gene

1988 • 246 citations

Two regions of the adenovirus early region 1A proteins are required for transformation

1988 • 232 citations

Growth inhibition by transforming growth factor beta (TGF-beta) type I is restored in TGF-beta-resistant hepatoma cells after expression of TGF-beta receptor type II cDNA.

1993 • 192 citations

Adenovirus E1A products suppress myogenic differentiation and inhibit transcription from muscle-specific promoters

1988 • 183 citations

TGF-beta 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector.

1992 • 182 citations

The transforming growth factor beta receptors types I, II, and III form hetero-oligomeric complexes in the presence of ligand.

1993 • 181 citations

Differential sensitivity of human colonic adenoma and carcinoma cells to transforming growth factor beta (TGF-beta): conversion of an adenoma cell line to a tumorigenic phenotype is accompanied by a reduced response to the inhibitory effects of TGF-beta.

1991 • 174 citations

Regulation of growth and differentiation of human keratinocytes by type beta transforming growth factor and epidermal growth factor.

1987 • 124 citations

Human cyclin A and the retinoblastoma protein interact with similar but distinguishable sequences in the adenovirus E1A gene product.

1991 • 116 citations

Characterization of the Promoter Region of the Human Transforming Growth Factor-β Type II Receptor Gene

1995 • 116 citations

Transcriptional Regulation of the Transforming Growth Factor β1 Promotor by v-src Gene Products Is Mediated through the AP-1 Complex

1990 • 115 citations

Nerve growth factor induces transcription of transforming growth factor-beta 1 through a specific promoter element in PC12 cells.

1994 • 93 citations

Regulation of MyoD gene transcription and protein function by the transforming domains of the adenovirus E1A oncoprotein.

1993 • 83 citations

Overexpression of human cyclin D1 reduces the transforming growth factor beta (TGF-beta) type II receptor and growth inhibition by TGF-beta 1 in an immortalized human esophageal epithelial cell line.

1994 • 71 citations

Induction of transforming growth factor beta 1 resistance by the E1A oncogene requires binding to a specific set of cellular proteins.

1991 • 69 citations

Narrow and variable lines in the ultraviolet spectrum of the Seyfert galaxy NGC4151

1985 • 67 citations

Abortive Infection and Malignant Transformation by Adenoviruses: Integration of Viral Dna and Control of Viral Gene Expression by Specific Patterns of DNA Methylation

1991 • 50 citations

Induction of transforming growth factor beta 1 and its receptor expression during myeloid leukemia cell differentiation.

1994 • 37 citations

Transforming growth factor-β receptors: Role in physiology and disease

1996 • 29 citations

The E1A oncogene induces resistance to the effects of 1,25-dihydroxyvitamin D3 on inhibition of growth of mouse keratinocytes.

1994 • 5 citations