Liver-Derived Hepatitis C Virus(HCV)-Specific CD4+ T Cells Recognize Multiple HCV Epitopes and Produce Interferon Gamma

Histological grading and staging of chronic hepatitis

1995 • 4,862 citations

The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994

1999 • 3,083 citations

Classification of hepatitis C virus into six major genotypes and a series of subtypes by phylogenetic analysis of the NS-5 region

1993 • 1,401 citations

Epidemiology of hepatitis C

1997 • 1,112 citations

The Declining Risk of Post-Transfusion Hepatitis C Virus Infection

1992 • 727 citations

Recurrence of hepatitis C virus after loss of virus-specific CD4+ T-cell response in acute hepatitis C

1999 • 716 citations

Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection

1995 • 702 citations

Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response.

1996 • 669 citations

Natural history of hepatitis C

1997 • 419 citations

Th1/Th2 profiles in tuberculosis, based on the proliferation and cytokine response of blood lymphocytes to mycobacterial antigens.

1994 • 309 citations

Different cytokine profiles of intraphepatic T cells in chronic hepatitis B and hepatitis C virus infections

1997 • 306 citations

Immunodominant CD4+ T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection

1997 • 306 citations

Compartmentalization of T lymphocytes to the site of disease: intrahepatic CD4+ T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C.

1993 • 247 citations

T-cell response to structural and nonstructural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infections

1994 • 239 citations

Mapping of immunodominant CD4+ T lymphocyte epitopes of hepatitis C virus antigens and their relevance during the course of chronic infection

1995 • 149 citations

Conserved hepatitis C virus sequences are highly immunogenic for CD4+ T cells: Implications for vaccine development

1999 • 143 citations

Intrahepatic hepatitis C virus-specific cytotoxic T lymphocyte activity and response to interferon alfa therapy in chronic hepatitis C

1998 • 137 citations

Number of interleukin‐4‐ and interferon‐γ‐secreting human T cells reactive with tetanus toxoid and the mycobacterial antigen PPD or phytohemagglutinin: distinct response profiles depending on the type of antigen used for activation

1993 • 97 citations

Idiotype‐specific T cells in multiple myeloma stage I: an evaluation by four different functional tests

1995 • 75 citations

Characteristics of the intrahepatic cytotoxic T lymphocyte response in chronic hepatitis C virus infection

1997 • 49 citations

Bystander Activation by Cytokines of Intrahepatic T Cells in Chronic Viral Hepatitis

1997 • 40 citations

Triple immunofluorescence flow cytometry, using whole blood, of CD4+ and CD8+ lymphocytes expressing CD45RO and CD45RA

1993 • 33 citations

Risk of hepatitis C virus (HCV) transmission by anti-HCV-negative blood components in Austria and Germany

1996 • 25 citations