Sulindac sulfide alters the expression of cyclin proteins in HT-29 colon adenocarcinoma cells

Principles of CDK regulation

1995 • 3,267 citations

G1 phase progression: Cycling on cue

1994 • 2,706 citations

Mammalian G1 cyclins

1993 • 1,990 citations

Treatment of Colonic and Rectal Adenomas with Sulindac in Familial Adenomatous Polyposis

1993 • 1,739 citations

Aspirin Use and the Risk for Colorectal Cancer and Adenoma in Male Health Professionals

1994 • 804 citations

Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway

1996 • 613 citations

Incidence of Cancer Among Patients With Rheumatoid Arthritis

1993 • 596 citations

Sulindac for polyposis of the colon

1983 • 521 citations

Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis.

1995 • 433 citations

Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells.

1995 • 420 citations

Cyclin D1 is an essential mediator of apoptotic neuronal cell death.

1996 • 383 citations

Nonsteroidal Antiinflammatory Drugs Inhibit the Proliferation of Colon Adenocarcinoma Cells: Effects on Cell Cycle and Apoptosis

1996 • 343 citations

Increased expression of cyclin D1 is an early event in multistage colorectal carcinogenesis

1996 • 318 citations

Amplification of cyclin genes in colorectal carcinomas.

1993 • 197 citations

Cyclins, CDKs and cancer

1995 • 176 citations

G1 delay in cells overexpressing prostaglandin endoperoxide synthase-2.

1996 • 173 citations

The anti-proliferative effect of sulindac and sulindac sulfide on HT-29 colon cancer cells: alterations in tumor suppressor and cell cycle-regulatory proteins.

1996 • 151 citations

Effect of aspirin on induction of apoptosis in HT-29 human colon adenocarcinoma cells

1998 • 134 citations

Growth imbalance and altered expression of cyclins B1, A, E, and D3 in MOLT-4 cells synchronized in the cell cycle by inhibitors of DNA replication.

1995 • 125 citations

Unscheduled expression of cyclin B1 and cyclin E in several leukemic and solid tumor cell lines.

1994 • 124 citations

Concurrent amplification of cyclin E and CDK2 genes in colorectal carcinomas

1995 • 114 citations

Cyclin D1 as a cellular proto-oncogene

1995 • 111 citations

Apoptosis induced by ectopic expression of cyclin D1 but not cyclin E.

1996 • 108 citations

Different expression patterns of cyclins A, D1 and E in human colorectal cancer

1996 • 82 citations

G1 arrest and down-regulation of cyclin E/cyclin-dependent kinase 2 by the protein kinase inhibitor staurosporine are dependent on the retinoblastoma protein in the bladder carcinoma cell line 5637.

1996 • 60 citations

Cyclin D3 Sensitizes Tumor Cells to Tumor Necrosis Factor-Induced, c-Myc-Dependent Apoptosis

1996 • 57 citations

Sulindac sulfide inhibits the proliferation of colon cancer cells: diminished expression of the proliferation markers PCNA and Ki-67

1997 • 52 citations

Threshold expression of cyclin E but not D type cyclins characterizes normal and tumour cells entering S phase

1995 • 39 citations

Expression of cyclins A, D2 and D3 in individual normal mitogen stimulated lymphocytes and in MOLT-4 leukemic cells analyzed by multiparameter flow cytometry.

1995 • 34 citations

Uncoupling of DNA replication and cell cycle progression by human cyclin E.

1996 • 22 citations