A Molecular Glimpse of Vesicular Monoamine Transporters

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE

1989 • 2,060 citations

Cloning and expression of a rat brain L-glutamate transporter

1992 • 1,230 citations

Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain.

1992 • 1,185 citations

Neurotransmitter Transporters: Recent Progress

1993 • 1,089 citations

Cloning and Expression of a Rat Brain GABA Transporter

1990 • 873 citations

Emerging Principles for the Recognition of Peptide Antigens by MHC Class I Molecules

1992 • 730 citations

Is the multidrug transporter a flippase?

1992 • 720 citations

A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter

1992 • 594 citations

The molecular mechanism of "ecstasy" [3,4-methylenedioxy-methamphetamine (MDMA)]: serotonin transporters are targets for MDMA-induced serotonin release.

1992 • 526 citations

Uptake of Catecholamines by a Particulate Fraction of the Adrenal Medulla

1962 • 510 citations

Expression cloning of a reserpine-sensitive vesicular monoamine transporter.

1992 • 481 citations

Nucleotide sequence and characterization of the Staphylococcus aureus norA gene, which confers resistance to quinolones

1990 • 479 citations

Mechanism of Transport and Storage of Neurotransmitter

1987 • 471 citations

From synapse to vesicle: The reuptake and storage of biogenic amine neurotransmitters

1993 • 461 citations

Emr, an Escherichia coli locus for multidrug resistance.

1992 • 410 citations

Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: A mechanism of action

1990 • 380 citations

Efflux-mediated multidrug resistance in Bacillus subtilis: similarities and dissimilarities with the mammalian system.

1991 • 367 citations

The Caenorhabditis elegans unc-17 Gene: a Putative Vesicular Acetylcholine Transporter

1993 • 361 citations

The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of streptomyces

1991 • 357 citations

Membrane transport proteins: implications of sequence comparisons

1992 • 330 citations

Accumulation of biological amines into chromaffin granules: a model for hormone and neurotransmitter transport

1988 • 323 citations

Mental Depression in Hypertensive Patients Treated for Long Periods with Large Doses of Reserpine

1954 • 306 citations

Efflux-mediated antiseptic resistance gene qacA from Staphylococcus aureus: common ancestry with tetracycline- and sugar-transport proteins

1990 • 304 citations

Drugs which block the storage of 5-hydroxytryptamine and related amines

1966 • 294 citations

Amphetamine and Other Weak Bases Act to Promote Reverse Transport of Dopamine in Ventral Midbrain Neurons

1993 • 290 citations

The plant vacuole : a multifunctional compartment

1993 • 219 citations

Bioenergetics of secretory vesicles

1986 • 211 citations

Calcium-sensitive cls mutants of Saccharomyces cerevisiae showing a Pet- phenotype are ascribable to defects of vacuolar membrane H(+)-ATPase activity

1991 • 191 citations

GABA and glycine in synaptic vesicles: storage and transport characteristics

1991 • 191 citations

Glutamate transport into synaptic vesicles. Roles of membrane potential, pH gradient, and intravesicular pH.

1992 • 178 citations

Radioligands of the vesicular monoamine transporter and their use as markers of monoamine storage vesicles

1989 • 164 citations

Functional Identification and Molecular Cloning of a Human Brain Vesicle Monoamine Transporter

1993 • 154 citations

The biological fate of reserpine.

1976 • 146 citations

Amphetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters.

1993 • 142 citations

Topology, structure and evolution of two families of proteins involved in antibiotic and antiseptic resistance in eukaryotes and prokaryotes — an analysis

1993 • 141 citations

Proton gradient linkage to active uptake of [3H]acetylcholine by Torpedo electric organ synaptic vesicles

1982 • 135 citations

Rat adrenal medulla: Levels of chromogranins, enkephalins, dopamine β-hydroxylase and of the amine transporter are changed by nervous activity and hypophysectomy

1987 • 131 citations

Reserpine binding to bovine chromaffin granule membranes. Characterization and comparison with dihydrotetrabenazine binding.

1984 • 127 citations

Characterization of the monoamine carrier of chromaffin granule membrane by binding of [2-3H]dihydrotetrabenazine.

1983 • 126 citations

Glutamate transporters from brain

1993 • 125 citations

ATR1, a Saccharomyces cerevisiae gene encoding a transmembrane protein required for aminotriazole resistance.

1988 • 122 citations

Active transport of gamma-aminobutyric acid and glycine into synaptic vesicles.

1989 • 119 citations

p-Chloroamphetamine induces serotonin release through serotonin transporters

1992 • 103 citations

Subcellular compartmentalization of 1-methyl-4-phenylpyridinium with catecholamines in adrenal medullary chromaffin vesicles may explain the lack of toxicity to adrenal chromaffin cells.

1987 • 101 citations

Dihydrotetrabenazine Binding and Monoamine Uptake in Mouse Brain Regions

1986 • 100 citations

Uptake of meta-iodobenzylguanidine by bovine chromaffin granule membranes.

1986 • 98 citations

Evidence that an ATPase and a protonmotive force function in the transport of acetylcholine into storage vesicles.

1980 • 97 citations

A gamma-aminobutyric acid transporter driven by a proton pump is present in synaptic-like microvesicles of pancreatic beta cells.

1993 • 94 citations

Lipophilic cations: a group of model substrates for the multidrug-resistance transporter

1992 • 94 citations

Nucleotide sequence analysis reveals similarities between proteins determining methylenomycin A resistance in Streptomyces and tetracycline resistance in eubacteria

1987 • 93 citations

Structural conservation and functional diversity of V-ATPases

1992 • 91 citations

Energetics of reserpine binding and occlusion by the chromaffin granule biogenic amine transporter

1990 • 90 citations

Energy-driven uptake of the neurotoxin 1-methyl-4-phenylpyridinium into chromaffin granules via the catecholamine transporter.

1988 • 88 citations

Reserpine binding to chromaffin granules suggests the existence of two conformations of the monoamine transporter

1989 • 86 citations

Reserpine binding to a vesicular amine transporter expressed in Chinese hamster ovary fibroblasts.

1993 • 84 citations

A human synaptic vesicle monoamine transporter cDNA predicts posttranslational modifications, reveals chromosome 10 gene localization and identifies TaqI RFLPs

1993 • 79 citations

Expression and regulation of the bovine vesicular monoamine transporter gene

1993 • 78 citations

Identification and purification of a functional amine transporter from bovine chromaffin granules.

1990 • 69 citations

Cloning and functional expression of a tetrabenazine sensitive vesicular monoamine transporter from bovine chromaffin granules

1994 • 67 citations

Chromosomal localization of the human vesicularamine transporter genes

1993 • 67 citations

The structure and biochemistry of the vacuolar H+ ATPase in proximal and distal urinary acidification

1992 • 61 citations

pH‐Dependence of the ATP‐Driven Uptake of Noradrenaline by Bovine Chromaffin‐Granule Ghosts

1981 • 56 citations

Conditions required for reserpine binding to the catecholamine transporter on chromaffin granule ghosts

1982 • 55 citations

Glutamate uptake into synaptic vesicles of bovine cerebral cortex and electrochemical potential difference of proton across the membrane

1989 • 49 citations

Functional asymmetry of the amine transporter from chromaffin granules.

1983 • 48 citations

EFFECT OF NEUROLEPTICS AND OTHER DRUGS ON MONOAMINE UPTAKE BY MEMBRANES OF ADRENAL CHROMAFFIN GRANULES

1977 • 47 citations

Mechanism of organic cation transport in rabbit renal basolateral membrane vesicles

1990 • 47 citations

Homology of a vesicular amine transporter to a gene conferring resistance to 1-methyl-4-phenylpyridinium.

1992 • 39 citations

Regulation of the Chromaffin Granule Catecholamine Transporter in Cultured Bovine Adrenal Medullary Cells: Stimulus–Biosynthesis Coupling

1992 • 38 citations

Zwitterionic and Anionic Forms of a Serotonin Analog as Transport Substrates

1989 • 35 citations

Characteristics of the transport of the quaternary ammonium 1-methyl-4-phenylpyridinium by chromaffin granules

1988 • 33 citations

Characterization and purification of the monoamine transporter of bovine chromaffin granules

1992 • 33 citations

Bacteriorhodopsin drives the glutamate transporter of synaptic vesicles after co-reconstitution.

1990 • 33 citations

Specific interaction of 5-(N-methyl-N-isobutyl)amiloride with the organic cation-proton antiporter in human placental brush-border membrane vesicles. Transport and binding.

1992 • 30 citations

Reserpic acid as an inhibitor of norepinephrine transport into chromaffin vesicle ghosts.

1985 • 22 citations

Chemical evidence that catecholamines are transported across the chromaffin granule membrane as noncationic species.

1983 • 22 citations

Induction of the vesicular monoamine transporter by elevated potassium concentration in cultures of rat sympathetic neurons

1990 • 21 citations

Purification of a [3H]dihydrotetrabenazine-binding protein from bovine adrenal medulla.

1991 • 20 citations

Does the carrier of chromaffin granules transport the protonated or the uncharged species of catecholamines?

1985 • 20 citations

Inhibition of Norepinephrine Transport and Reserpine Binding by Reserpine Derivatives

1987 • 14 citations

Fluorescence analysis of the interaction of isometamidium with Trypanosoma congolense

1993 • 12 citations