Human T-cell leukemia virus type I tax protein induces the expression of anti-apoptotic gene Bcl-xL in human T-cells through nuclear factor-kappaB and c-AMP responsive element binding protein pathways.

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

1980 • 5,022 citations

Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human sera.

1981 • 2,281 citations

Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease.

1982 • 2,170 citations

Diagnostic criteria and classification of clinical subtypes of adult T‐cell leukaemia‐lymphoma

1991 • 1,527 citations

Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T cells

1981 • 1,429 citations

Induction of bcl-2 expression by epstein-barr virus latent membrane protein 1 protects infected B cells from programmed cell death

1991 • 1,195 citations

Trans -Acting Transcriptional Activation of the Long Terminal Repeat of Human T Lymphotropic Viruses in Infected Cells

1984 • 781 citations

A human beta-actin expression vector system directs high-level accumulation of antisense transcripts.

1987 • 767 citations

The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins.

1992 • 665 citations

Isolation and Transmission of Human Retrovirus (Human T-Cell Leukemia Virus)

1983 • 568 citations

NF-κB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

1999 • 526 citations

The tat Gene of Human T-Lymphotropic Virus Type 1 Induces Mesenchymal Tumors in Transgenic Mice

1987 • 522 citations

Conversion of lytic to persistent alphavirus infection by the bcl-2 cellular oncogene

1993 • 495 citations

Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro.

1990 • 439 citations

Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes.

1990 • 401 citations

Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I.

1995 • 364 citations

HTLV‐I Uveitis: A Distinct Clinical Entity Caused by HTLV‐I

1992 • 292 citations

A novel T-cell line derived from adult T-cell leukemia.

1980 • 224 citations

Induction of Bcl-x_LExpression by Human T-Cell Leukemia Virus Type 1 Tax through NF-κB in Apoptosis-Resistant T-Cell Transfectants with Tax

1999 • 214 citations

Cell surface phenotypes and expression of viral antigens of various human cell lines carrying human T‐cell leukemia virus

1984 • 193 citations

Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro

1990 • 181 citations

Persistent activation of NF-κB by the Tax transforming protein of HTLV-1: hijacking cellular IκB kinases

1999 • 181 citations

Transactivation of the interleukin-1alpha promoter by human T-cell leukemia virus type I and type II Tax proteins

1996 • 167 citations

Human T-cell leukemia virus type 1 Tax protein transforms rat fibroblasts via two distinct pathways

1997 • 139 citations

Repression of Bax Gene Expression by the HTLV-I Tax Protein: Implications for Suppression of Apoptosis in Virally Infected Cells

1997 • 131 citations

A trans-activator Tax of human T-cell leukemia virus type 1 binds to NF-kappa B p50 and serum response factor (SRF) and associates with enhancer DNAs of the NF-kappa B site and CArG box.

1993 • 129 citations

Characterization of T cells immortalized by Tax1 of human T-cell leukemia virus type 1

1995 • 119 citations

Characterization of a novel HTLV-infected cell line

1984 • 116 citations

Inhibition of Apoptosis in T Cells Expressing Human T Cell Leukemia Virus Type I Tax

1994 • 112 citations

Electroporation: application to human lympboid cell lines for stable introduction of a transactivator gene of human T-cell leukemia virus type I

1989 • 88 citations

Molecular Mechanisms of Promoter Regulation of the gp34 Gene That Is Trans-activated by an Oncoprotein Tax of Human T Cell Leukemia Virus Type I

1998 • 40 citations

Isolation and characterization of the tax protein of HTLV-I.

1989 • 26 citations