A CDKN2 -like polymorphism in Xiphophorus LG V is associated with UV-B-induced melanoma formation in platyfish–swordtail hybrids

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations

1987 • 6,762 citations

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1993 • 3,680 citations

‘Touchdown’ PCR to circumvent spurious priming during gene amplification

1991 • 2,630 citations

Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus

1994 • 860 citations

Wavelengths effective in induction of malignant melanoma.

1993 • 739 citations

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.

1994 • 731 citations

Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

1995 • 653 citations

Mutations and altered expression of p16INK4 in human cancer.

1994 • 547 citations

Cutaneous Melanoma

1991 • 397 citations

Novel putative receptor tyrosine kinase encoded by the melanoma-inducing Tu locus in Xiphophorus

1989 • 337 citations

Identification of Human and Mouse p19, a Novel CDK4 and CDK6 Inhibitor with Homology to p16^ink4

1995 • 336 citations

Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds

1995 • 316 citations

Loss of expression of the p16/cyclin-dependent kinase inhibitor 2 tumor suppressor gene in melanocytic lesions correlates with invasive stage of tumor progression.

1995 • 261 citations

Animal model for ultraviolet radiation-induced melanoma: platyfish-swordtail hybrid.

1989 • 205 citations

The Platyfish, Xiphophorus maculatus

1975 • 188 citations

cDNA sequence for human erythrocyte ankyrin.

1990 • 166 citations

The rate of malignant melanoma in the United States: Are we making an impact?

1987 • 128 citations

CDKN2 explains part of the clinical phenotype in Dutch familial atypical multiple-mole melanoma (FAMMM) syndrome families

1995 • 112 citations

SUNLIGHT AND CUTANEOUS MALIGNANT MELANOMA: EVIDENCE FOR AND AGAINST CAUSATION

1990 • 110 citations

Evidence for u.v. induction of CDKN2 mutations in melanoma cell lines.

1995 • 107 citations

Platyfish and swordtails: a genetic system for the analysis of molecular mechanisms in tumor formation

1995 • 96 citations

Etiology of cancer as studied in the platyfish-swordtail system

1978 • 95 citations

Tumor Suppression in Xiphophorus by an Accidentally Acquired Promoter

1993 • 93 citations

Germline p16INK4A mutation and protein dysfunction in a family with inherited melanoma.

1995 • 85 citations

Genetic control of cell differentiation in platyfish‐swordtail melanomas

1976 • 70 citations

Nonmammalian Models for Sunlight Carcinogenesis: Genetic Analysis of Melanoma Formation in Xiphophorus Hybrid Fish

1996 • 64 citations

Using mismatched primer-template pairs in touchdown PCR.

1994 • 62 citations

Genetic linkage map of fishes of the genus Xiphophorus (Teleostei: Poeciliidae).

1991 • 62 citations

Spontaneous melanoma formation in nonhybrid Xiphophorus.

1995 • 61 citations

A Method for Artificial Insemination in Viviparous Fishes

1950 • 57 citations

Homology of melanoma-inducing loci in the genus Xiphophorus.

1990 • 52 citations

Linkage between a regulatory locus for melanoma cell differentiation and an esterase locus in Xiphophorus

1980 • 49 citations

Genetic mapping in Xiphophorus hybrid fish: assignment of 43 AP-PCR/RAPD and isozyme markers to multipoint linkage groups.

1996 • 49 citations

Genetics of Melanomas in Xiphophorus Fishes

1989 • 48 citations

Ligand-dependent tumor induction in medakafish embryos by a Xmrk receptor tyrosine kinase transgene.

1994 • 44 citations

v-erbB related sequences in Xiphophorus that map to melanoma determining Mendelian loci and overexpress in a melanoma cell line.

1988 • 42 citations

THREE LINKED ENZYME LOCI IN FISHES: IMPLICATIONS IN THE EVOLUTION OF VERTEBRATE CHROMOSOMES

1977 • 38 citations

Differences in transcription and promoters of Xmrk-1 and Xmrk-2 genes suggest a role for Xmrk-2 in pigment pattern development in the platyfish, Xiphophorus maculatus.

1994 • 35 citations

The 1988 catalog of mapped genes and report of the nomenclature committee

1988 • 35 citations

Enhanced evolutionary PCR using oligonucleotides with inosine at the 3′-terminus

1991 • 33 citations

Linkage Group V of Platyfishes and Swordtails of the Genus <italic>Xiphophorus</italic> (Poeciliidae): Linkage of Loci for Malate Oehydrogenase-2 and Esterase-1 and Esterase-4 With a Gene ContrOlling the Severity of Hybrid Melanomas<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1983 • 31 citations

Genetics of Cutaneous Melanoma

1994 • 28 citations

Influence of Ozone Depletion on the Incidence of Skin Cancer

1993 • 20 citations

Analysis of an esterase linked to a locus involved in the regulation of the melanoma oncogene and isolation of polymorphic marker sequences inXiphophorus

1991 • 18 citations

Stable Association of a Pigmentation Allele With an Oncogene: Nonhybrid Melanomas in Xiphophorus variatus

1995 • 18 citations

The Hereditary Basis for Melanosis in Hybrids of Mexican Killifishes

1931 • 17 citations

Cloning and gene map assignment of the Xiphophorus DNA ligase 1 gene.

1993 • 16 citations

Assignment of an erbB-like DNA sequence to linkage group VI in fishes of the genus Xiphophorus (poeciliidae)

1990 • 15 citations

Assignment of the TP53 orthologue to a new linkage group (LG XIV) in fish of the genus xiphophorus (Teleostei: Poeciliidae)

1996 • 12 citations

Genetics of Cutaneous Melanoma.

1994 • 12 citations

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