Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours

Telomeres shorten during ageing of human fibroblasts

1990 • 5,530 citations

Telomerase Catalytic Subunit Homologs from Fission Yeast and Human

1997 • 2,256 citations

Telomere length predicts replicative capacity of human fibroblasts.

1992 • 2,209 citations

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

1992 • 2,096 citations

hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization

1997 • 1,786 citations

Telomere reduction in human colorectal carcinoma and with ageing

1990 • 1,672 citations

Histological Typing of Lung and Pleural Tumours

1999 • 1,538 citations

A telomerase component is defective in the human disease dyskeratosis congenita

1999 • 1,135 citations

Correlating telomerase activity levels with human neuroblastoma outcomes

1995 • 631 citations

Telomerase activity in normal leukocytes and in hematologic malignancies

1995 • 619 citations

Akt Protein Kinase Enhances Human Telomerase Activity through Phosphorylation of Telomerase Reverse Transcriptase Subunit

1999 • 479 citations

Telomerase Activity in Small-Cell and Non-Small-Cell Lung Cancers

1995 • 447 citations

Telomerase activity in gastric cancer.

1995 • 433 citations

Expression of TERT in early premalignant lesions and a subset of cells in normal tissues

1998 • 386 citations

Reversing Time: Origin of Telomerase

1998 • 308 citations

Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT)

1999 • 270 citations

Subnuclear shuttling of human telomerase induced by transformation and DNA damage

2002 • 253 citations

Cutting Edge: Telomerase Activation in Human T Lymphocytes Does Not Require Increase in Telomerase Reverse Transcriptase (hTERT) Protein But Is Associated with hTERT Phosphorylation and Nuclear Translocation

2001 • 235 citations

Role of telomerase in cellular proliferation and cancer

1999 • 228 citations

Telomerase activity in human brain tumours

1995 • 217 citations

Protein Phosphatase 2A Inhibits Nuclear Telomerase Activity in Human Breast Cancer Cells

1997 • 197 citations

High Telomerase Activity in Primary Lung Cancers: Association With Increased Cell Proliferation Rates and Advanced Pathologic Stage

1997 • 194 citations

Basal cell (basaloid) carcinoma of the lung: A new morphologic and phenotypic entity with separate prognostic significance

1992 • 193 citations

Telomerase expression in respiratory epithelium during the multistage pathogenesis of lung carcinomas.

1997 • 173 citations

Complex regulatory mechanisms of telomerase activity in normal and cancer cells: How can we apply them for cancer therapy?

2002 • 169 citations

Immuno-histochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue sections

1999 • 153 citations

Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase

2000 • 153 citations

The Nucleolar Localization Domain of the Catalytic Subunit of Human Telomerase

2002 • 134 citations

TELOMERES AND TELOMERASE IN HUMAN CANCER (REVIEW)

1995 • 106 citations

Telomerase activity as a prognostic indicator in stage I non-small cell lung cancer.

1999 • 103 citations

Telomerase activity and expression of human telomerase RNA component and human telomerase reverse transcriptase in lung carcinomas

2001 • 91 citations

hTERT expression is a prognostic factor of survival in patients with stage I non-small cell lung cancer.

2002 • 85 citations

Clinicopathologic significance of telomerase activity and hTERT mRNA expression in non-small cell lung cancer

2001 • 58 citations

Effects of N-(4-Hydroxyphenyl)retinamide on hTERT Expression in the Bronchial Epithelium of Cigarette Smokers

2001 • 58 citations

Immuno-histochemical detection of human telomerase reverse transcriptase in human liver tissues

2000 • 57 citations

Prediction of Survival in Stage I Lung Carcinoma Patients by Telomerase Function Evaluation

2002 • 49 citations

Expression of Telomerase Reverse Transcriptase (TERT) in Malignant Mesotheliomas

2002 • 49 citations

Expression of human telomerase RNA component and telomerase reverse transcriptase mRNA in atypical adenomatous hyperplasia of the lung

2002 • 44 citations

Careful histological confirmation and microdissection reveal telomerase activity in otherwise telomerase-negative breast cancers.

1998 • 44 citations

Comparison of oncogene mutation detection and telomerase activity for the molecular staging of non-small cell lung cancer.

1997 • 42 citations

Evaluation of telomerase activity in bronchial lavage as a potential diagnostic marker for malignant lung disease

2000 • 36 citations

hTERT expression in sporadic renal cell carcinomas

2001 • 26 citations

Telomerase activity in non-small cell lung carcinomas correlates with smoking status.

1999 • 25 citations

Telomerase Activity in Pulmonary Neuroendocrine Tumors

2000 • 23 citations

Detection of telomerase expression in fine-needle aspirations and fluids

1998 • 22 citations

Telomerase Activity Significantly Correlates with Chromosome Alterations, Cell Differentiation, and Proliferation in Lung Adenocarcinomas

2000 • 22 citations

Immune function, telomerase, and angiogenesis in patients with primary, operable nonsmall cell lung carcinoma

2001 • 21 citations

Pathology of lung tumours

2011 • 9 citations

Immunohistochemical detection of human telomerase reverse transcriptase in human liver tissues

2000 • 3 citations

Deleted Work

1955 • 0 citations