A substance in L-929 cell extracts which replaces the ascorbate requirement for prolyl hydroxylase in a tritium release assay for reducing cofactor; correlation of its concentration with the extent of ascorbate-independent proline hydroxylation and the level of prolyl hydroxylase activity in these cells

Determination of protein: A modification of the lowry method that gives a linear photometric response

1972 • 5,490 citations

Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins

1971 • 1,396 citations

Biochemical characteristics and biological significance of the genetically-distinct collagens

1976 • 468 citations

ENZYMATIC REDUCTION OF FOLIC ACID AND DIHYDROFOLIC ACID TO TETRAHYDROFOLIC ACID

1957 • 416 citations

The effect of ascorbic acid on collagen polypeptide synthesis and proline hydroxylation during the growth of cultured fibroblasts

1972 • 377 citations

The Isolation and Characterization of Dihydropteridine Reductase from Sheep Liver

1972 • 256 citations

The role of ascorbate in the prolyl hydroxylase reaction

1978 • 211 citations

Hydroxylation of Proline in Synthetic Polypeptides with Purified Protocollagen Hydroxylase

1967 • 167 citations

Purification and properties of collagen proline hydroxylase from newborn rat skin

1970 • 152 citations

THE QUANTITATIVE DETERMINATION OF ASCORBIC ACID IN SMALL AMOUNTS OF WHITE BLOOD CELLS AND PLATELETS

1947 • 147 citations

The Ability of Purine and Thymine Derivatives and of Glycine to Support the Growth of Mammalian Cells in Culture

1959 • 136 citations

The stimulation of collagen secretion by ascorbate as a result of increased proline hydroxylation in chick embryo fibroblasts

1975 • 121 citations

Modification of the tritium-release assays for prolyl and lysyl hydroxylases using Dowex-50 columns

1975 • 99 citations

Collagen chain formation and peptidyl proline hydroxylation in monolayer tissue cultures of L-929 fibroblasts

1969 • 95 citations

Cell-free Collagen Synthesis on Membrane-bound Polysomes of Chick Embryo Connective Tissue and the Localization of Prolyl Hydroxylase on the Polysome-Membrane Complex

1973 • 85 citations

Collagen synthesis on polyribosomes of cultured mammalian fibroblasts

1967 • 84 citations

Further characterization of embryonic tendon fibroblasts and the use of immunoferritin techniques to study collagen biosynthesis.

1975 • 83 citations

A simple radioisotope assay for phenylalanine hydroxylase

1967 • 68 citations

The activation of protocollagen proline hydroxylase by ascorbic acid in cultured 3T6 fibroblasts

1974 • 64 citations

A simple radioisotope assay for phenylalanine hydroxylase cofactor

1967 • 64 citations

The synthesis of underhydroxylated collagen by 3T6 mouse fibroblasts in culture

1972 • 60 citations

Factors which stimulate collagen proline hydroxylase

1967 • 48 citations

Studies on sepiapterin reductase: Further characterization of the reaction product

1968 • 46 citations

The influence of ascorbic acid and tetrahydropteridine on the synthesis of hydroxyproline by cultured cells.

1967 • 42 citations

Submicrosomal localization of prolyl hydroxylase from chick embryo limb bone.

1976 • 40 citations

Mechanism of the hydrogen peroxide hemolysis test and its reversal with phenols

1971 • 32 citations

An activatable form of prolyl hydroxylase in fibroblast extracts

1975 • 29 citations

Ascorbate‐independent proline hydroxylation resulting from viral transformation of balb 3T3 cells and unaffected by dibutyryl camp treatment

1976 • 27 citations

Stability of Vitamins in a Chemically Defined Medium for 929-L Fibroblasts<xref ref-type="fn" rid="FN2">2</xref>

1963 • 20 citations

Phenylalanine hydroxylase from Pseudomonas sp. (ATCC 11299a). Purification, molecular weight, and influence of tyrosine metabolites on activation and hydroxylation.

1975 • 20 citations

Effects of Cortisol and 19-Nortestosterone¹on the Free Amino Acid Pools and Amino Acid Uptake of Cultured Cells

1967 • 18 citations

The free amino acid pool in L-strain fibroblasts

1962 • 16 citations