Further characterization of embryonic tendon fibroblasts and the use of immunoferritin techniques to study collagen biosynthesis.

An enzymic method for the trace iodination of immunoglobulins and other proteins

1969 • 1,414 citations

Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins

1971 • 1,396 citations

The thermal transition of a non-hydroxylated form of collagen. Evidence for a role for hydroxyproline in stabilizing the triple-helix of collagen

1973 • 563 citations

SYNTHESIS, MIGRATION, AND RELEASE OF PRECURSOR COLLAGEN BY ODONTOBLASTS AS VISUALIZED BY RADIOAUTOGRAPHY AFTER [3H]PROLINE ADMINISTRATION

1974 • 376 citations

Synthesis and extrusion of collagen by freshly isolated cells from chick embryo tendon

1971 • 280 citations

Hydroxyproline content determines the denaturation temperature of chick tendon collagen

1973 • 224 citations

THE DISTRIBUTION AND ASYMMETRY OF MAMMALIAN CELL SURFACE SACCHARIDES UTILIZING FERRITIN-CONJUGATED PLANT AGGLUTININS AS SPECIFIC SACCHARIDE STAINS

1974 • 223 citations

AN ULTRASTRUCTURAL STAINING METHOD FOR ENHANCING THE SIZE AND ELECTRON OPACITY OF FERRITIN IN THIN SECTIONS

1972 • 208 citations

Distribution of Saccharide Residues on Membrane Fragments from a Myeloma-Cell Homogenate: Its Implications for Membrane Biogenesis

1972 • 185 citations

Hydroxylation of Proline and the Intracellular Accumulation of a Polypeptide Precursor of Collagen

1966 • 180 citations

SECRETION OF COLLAGEN BY CORNEAL EPITHELIUM

1973 • 179 citations

Pressure homogenization of mammalian tissues

1961 • 179 citations

Two improved methods for preparing ferritin-protein conjugates for electron microscopy.

1975 • 168 citations

Affinity Column Purification of Protocollagen Proline Hydroxylase from Chick Embryos and Further Characterization of the Enzyme

1973 • 168 citations

Decarboxylation of alpha-ketoglutarate coupled to collagen proline hydroxylase.

1968 • 127 citations

Purification of carbon-14-labeled protocollagen and its hydroxylation by prolyl-hydroxylase

1973 • 120 citations

Influence of chelating agents on the biosynthesis of collagen

1965 • 119 citations

Purification and partial characterization of the enzyme for the hydroxylation of proline in protocollagen

1967 • 106 citations

Collagen Synthesis: Localization of Prolyl Hydroxylase in Tendon Cells Detected with Ferritin-Labeled Antibodies

1973 • 105 citations

Intracellular Collagen and Protocollagen from Embryonic Tendon Cells

1973 • 103 citations

Formation of interchain disulfide bonds and helical structure during biosynthesis of procollagen by embryonic tendon cells

1974 • 102 citations

A Transport Form of Collagen from Embryonic Tendon: Electron Microscopic Demonstration of an NH ₂ -Terminal Extension and Evidence Suggesting the Presence of Cystine in the Molecule

1972 • 98 citations

Immunoferritin Localization of Intracellular Antigens: The Use of Ultracryotomy to Obtain Ultrathin Sections Suitable for Direct Immunoferritin Staining

1973 • 89 citations

THE GOLGI APPARATUS IN CHICK CORNEAL EPITHELIUM: CHANGES IN INTRACELLULAR POSITION DURING DEVELOPMENT

1970 • 89 citations

A General Method for the Specific Staining of Intracellular Antigens with Ferritin-Antibody Conjugates

1970 • 87 citations

Activation of Prolyl Hydroxylase in L-929 Fibroblasts by Ascorbic Acid

1973 • 86 citations

Cell-free Collagen Synthesis on Membrane-bound Polysomes of Chick Embryo Connective Tissue and the Localization of Prolyl Hydroxylase on the Polysome-Membrane Complex

1973 • 85 citations

Collagen synthesis on polyribosomes of cultured mammalian fibroblasts

1967 • 84 citations

Ferritin-Conjugated Antibodies Used for Labeling of Organelles Involved in the Cellular Synthesis and Transport of Procollagen

1974 • 81 citations

Calf Tendon Procollagen Peptidase: Its Purification and Endopeptidase Mode of Action

1974 • 79 citations

Secretion and Extracellular Processing of Procollagen by Cultured Human Fibroblasts

1973 • 71 citations

Procollagen-A Precursor Form of Collagen

1973 • 68 citations

Solid-Phase Conjugation of Ferritin to Fab-Fragments of Immunoglobulin G for Use in Antigen Localization on Thin Sections

1972 • 67 citations

Intracellular Hydroxylation of Non‐Helical Protocollagen to Form Triple‐Helical Procollagen and Subsequent Secretion of the Molecule

1974 • 65 citations

Formation of Enzyme-Substrate Complexes with Protocollagen Proline Hydroxylase and Large Polypeptide Substrates

1969 • 59 citations

Identification of a Disulfide-Linked Procollagen as the Biosynthetic Precursor of Chick-Bone Collagen

1973 • 57 citations

CHARACTERIZATION OF IMMUNOGLOBULIN STRUCTURES FROM THE SURFACE OF CHRONIC LYMPHOCYTIC LEUKEMIA CELLS

1971 • 43 citations

Antibodies to Chick‐Tendon Procollagen

1974 • 42 citations

Collagen Synthesis: A Disulfide-Linked Collagen Precursor in Chick Bone

1973 • 40 citations

Association of prolyl hydroxylase activity with membranes

1973 • 34 citations

Conformation of underhydroxylated collagen synthesized by 3T6 fibroblasts in culture

1973 • 28 citations

Labeled antibodies to protocollagen proline hydroxylase from chick embryos for intracellular localization of the enzyme

1972 • 25 citations