Antigen presenting ability of thymic macrophages and epithelial cells: Evidence for defects in the antigen processing function of thymic epithelial cells

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

The Staphylococcal Enterotoxins and Their Relatives

1990 • 1,914 citations

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

1989 • 1,095 citations

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

1978 • 870 citations

Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm

1992 • 825 citations

Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing.

1983 • 701 citations

The T Cell Receptor

1987 • 554 citations

In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cells

1977 • 534 citations

Antigen recognition by H-2-restricted T cells. II. A tryptic ovalbumin peptide that substitutes for processed antigen.

1984 • 351 citations

H-2 antigens of the thymus determinelymphocyte specificity

1978 • 321 citations

Identity of cells that imprint H–2-restricted T-cell specificity in the thymus

1986 • 267 citations

Positive selection of the T cell repertoire: Where and when does it occur?

1989 • 242 citations

IA antigens and antigen-presenting function of thymic macrophages.

1980 • 141 citations

Human thymic epithelial cells produce interleukin 1.

1987 • 136 citations

Evidence for effects of interleukin 4 (B cell stimulatory factor 1) on macrophages: enhancement of antigen presenting ability of bone marrow-derived macrophages.

1987 • 128 citations

The T cell repertoire may be biased in favor of MHC recognition

1986 • 121 citations

Interferon-gamma modulates HLA class II antigen expression on cultured human thymic epithelial cells.

1985 • 110 citations

Effect of isotypes and allelic polymorphism on the binding of staphylococcal exotoxins to MHC class II molecules.

1990 • 110 citations

Characterization of the gamma-interferon-mediated induction of antigen-presenting ability in P388D1 cells.

1983 • 101 citations

Thymic cortical epithelial cells lack full capacity for antigen presentation

1989 • 85 citations

Presentation of antigen, foreign major histocompatibility complex proteins and self by thymus cortical epithelium

1989 • 83 citations

Interferon-gamma is produced by activated immature mouse thymocytes and inhibits the interleukin 4-induced proliferation of immature thymocytes.

1987 • 50 citations

Phenotype of stromal cell‐associated thymocytes in situ is compatible with selection of the T cell repertoire at an “immature” stage of thymic T cell differentiation

1987 • 48 citations

Lymphokine-mediated induction of antigen-presenting ability in thymic stromal cells.

1987 • 44 citations

Effect of prostaglandin E2 on the γ-interferon induction of antigen-presenting ability in P388D1 cells and on IL-2 production by T-cell hybridomas

1985 • 35 citations