The neurotrophin receptor, gp75, forms a complex with the receptor tyrosine kinase TrkA.

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1987 • 1,703 citations

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1994 • 1,431 citations

The trk proto-oncogene encodes a receptor for nerve growth factor

1991 • 1,396 citations

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

1991 • 1,232 citations

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

1992 • 960 citations

Expression and structure of the human NGF receptor

1986 • 956 citations

Gene transfer and molecular cloning of the rat nerve growth factor receptor

1987 • 946 citations

Induction of Apoptosis by the Low-Affinity NGF Receptor

1993 • 774 citations

Neurotrophin receptors: A window into neuronal differentiation

1992 • 704 citations

Binding of brain-derived neurotrophic factor to the nerve growth factor receptor

1990 • 702 citations

Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor

1994 • 583 citations

PDGF β-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex

1990 • 561 citations

Trk receptors use redundant signal transduction pathways involving SHC and PLC-γ1 to mediate NGF responses

1994 • 538 citations

Sequestration of GPI-Anchored Proteins in Caveolae Triggered by Cross-Linking

1994 • 505 citations

A monoclonal antibody modulates the interaction of nerve growth factor with PC12 cells.

1984 • 503 citations

Nerve growth factor mediates signal transduction through trk homodimer receptors

1992 • 458 citations

Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells

1994 • 397 citations

p75LNGFR regulates Trk signal transduction and NGF-induced neuronal differentiation in MAH cells

1994 • 353 citations

Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation

1992 • 321 citations

High affinity nerve growth factor binding displays a faster rate of association than p140trk binding. Implications for multi-subunit polypeptide receptors.

1994 • 313 citations

Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors

1991 • 296 citations

The low affinity NGF receptor, p75, can collaborate with each of the Trks to potentiate functional responses to the neurotrophins

1994 • 294 citations

Demonstration of the retrograde transport of nerve growth factor receptor in the peripheral and central nervous system

1987 • 268 citations

NGF-stimulated retrograde transport of trkA in the mammalian nervous system.

1995 • 239 citations

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1989 • 235 citations

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1986 • 213 citations

The types II and III transforming growth factor-beta receptors form homo-oligomers.

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1980 • 142 citations

Positive and negative effects of neurotrophins on the isthmo-optic nucleus in chick embryos

1994 • 133 citations

A potential interaction of p75 and trkA NGF receptors revealed by affinity crosslinking and immunoprecipitation

1995 • 124 citations

Deletion of cytoplasmic sequences of the nerve growth factor receptor leads to loss of high affinity ligand binding.

1990 • 94 citations

Interaction with TrkA Immobilizes gp75 in the High Affinity Nerve Growth Factor Receptor Complex

1995 • 91 citations

Purification and Amino Terminal Sequencing of Human Melanoma Nerve Growth Factor Receptor

1987 • 87 citations

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1994 • 81 citations

Nerve Growth Factor (NGF) Induces Neuronal Differentiation in Neuroblastoma Cells Transfected with the NGF Receptor cDNA

1990 • 72 citations

Introduction of nerve growth factor (NGF) receptors into a medulloblastoma cell line results in expression of high- and low-affinity NGF receptors but not NGF-mediated differentiation.

1990 • 71 citations

Nerve growth factor receptors

1997 • 66 citations

Interactions of neurotrophin-3 (NT-3), brain-derived neurotrophic factor (BDNF), and the NT-3.BDNF heterodimer with the extracellular domains of the TrkB and TrkC receptors.

1994 • 61 citations

Isolation and chemical characterization of a melanoma-associated proteoglycan antigen

1983 • 60 citations

Identification of a conserved protein motif in a group of growth factor receptors

1990 • 57 citations

Dissociation of the receptor for immunoglobulin E in mild detergents

1985 • 50 citations

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1983 • 48 citations

Biochemical Analysis of Torso and D-Raf During Drosophila Embryogenesis: Implications for Terminal Signal Transduction

1993 • 47 citations

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1979 • 43 citations

Association of a purine-analogue-sensitive protein kinase activity with p75 nerve growth factor receptors.

1993 • 40 citations

Purification and characterization of the recombinant extracellular domain of human nerve growth factor receptor expressed in a baculovirus system.

1990 • 38 citations

Retrograde Axonal Transport and Lesion-Induced Upregulation of the TrkA High-Affinity NGF Receptor

1994 • 26 citations

Nerve growth factor receptors are preaggregated and immobile on responsive cells

1991 • 19 citations

Lateral diffusion of nerve growth factor receptor: modulation by ligand-binding and cell-associated factors.

1990 • 9 citations