CD38 Expression on CD8 T Lymphocytes as a Marker of Residual Virus Replication in Chronically HIV-Infected Patients Receiving Antiretroviral Therapy

Shorter Survival in Advanced Human Immunodeficiency Virus Type 1 Infection Is More Closely Associated with T Lymphocyte Activation than with Plasma Virus Burden or Virus Chemokine Coreceptor Usage

1999 • 1,017 citations

Quantifying Residual HIV-1 Replication in Patients Receiving Combination Antiretroviral Therapy

1999 • 824 citations

Persistence of HIV-1 Transcription in Peripheral-Blood Mononuclear Cells in Patients Receiving Potent Antiretroviral Therapy

1999 • 619 citations

Elevated CD38 Antigen Expression on CD8+ T Cells Is a Stronger Marker for the Risk of Chronic HIV Disease Progression to AIDS and Death in the Multicenter AIDS Cohort Study Than CD4+ Cell Count, Soluble Immune Activation Markers, or Combinations of HLA-DR and CD38 Expression

1997 • 551 citations

Residual HIV-1 RNA in Blood Plasma of Patients Taking Suppressive Highly Active Antiretroviral Therapy

1999 • 458 citations

Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy

2000 • 429 citations

The Follicular Dendritic Cell: Long Term Antigen Retention During Immunity

1980 • 377 citations

Human CD38, a cell‐surface protein with multiple functions

1996 • 303 citations

T-cell subset alterations in HIV-infected homosexual men: NIAID multicenter AIDS cohort study

1989 • 297 citations

Dynamics of viral load rebound and immunological changes after stopping effective antiretroviral therapy

1999 • 270 citations

CD8+ T-Lymphocyte Activation in HIV-1 Disease Reflects an Aspect of Pathogenesis Distinct From Viral Burden and Immunodeficiency

1998 • 234 citations

Increased number of primed activated CD8+CD38+CD45RO+T cells predict the decline of CD4+T cells in HIV-1-infected patients

1996 • 180 citations

Activation and Cell Cycle Antigens in CD4⁺and CD8⁺T Cells Correlate with Plasma Human Immunodeficiency Virus (HIV‐1) RNA Level in HIV‐1 Infection

1998 • 122 citations

CD8+, CD38+ Lymphocyte Percent

1997 • 118 citations

Highly active antiretroviral therapy during early HIV infection reverses T-cell activation and maturation abnormalities

1998 • 105 citations

Maximum suppression of HIV replication leads to the restoration of HIV-specific responses in early HIV disease

2000 • 94 citations

Quantitative Alterations of the Functionally Distinct Subsets of CD4 and CD8 T Lymphocytes in Asymptomatic HIV Infection

1997 • 89 citations

The Dominant Source of CD4+ and CD8+ T-Cell Activation in HIV Infection Is Antigenic Stimulation

2000 • 89 citations

Parallel decline of CD8+/CD38++ T cells and viraemia in response to quadruple highly active antiretroviral therapy in primary HIV infection

2002 • 86 citations

Quantitation of CD38 activation antigen expression on CD8+ T cells in HIV-1 infection using CD4 expression on CD4+ T lymphocytes as a biological calibrator

1998 • 81 citations

Increased levels of activated subsets of CD4 T cells add to the prognostic value of low CD4 T cell counts in a cohort of HIV-infected drug users

2000 • 76 citations

Effects of primary HIV-1 infection on subsets of CD4+ and CD8+ T lymphocytes

1995 • 75 citations

Three-color cytofluorometric analysis of CD8 cell subsets in HIV-1 infection.

1991 • 73 citations

Immunologic effects of combined protease inhibitor and reverse transcriptase inhibitor therapy in previously treated chronic HIV-1 infection

1998 • 71 citations

Changes in blood CD8+ lymphocyte activation status and plasma HIV RNA levels during antiretroviral therapy

1998 • 70 citations

Massive Activation of Immune Cells with an Intact T Cell Repertoire in Acute Human Immunodeficiency Virus Syndrome

1995 • 69 citations

Expression of CD28 and CD38 by CD8+ T lymphocytes in HIV-1 infection correlates with markers of disease severity and changes towards normalization under treatment

1999 • 61 citations

T cell changes after combined nucleoside analogue therapy in HIV primary infection

1999 • 50 citations

Immune Function and Phenotype Before and After Highly Active Antiretroviral Therapy

2006 • 47 citations

Activation of CD8 T cells normalizes and correlates with the level of infectious provirus in tonsils during highly active antiretroviral therapy in early HIV-1 infection

1999 • 37 citations

Immune Function and Phenotype Before and After Highly Active Antiretroviral Therapy

1999 • 34 citations

Comparison of T-Cell Subsets' Reconstitution After 12 Months of Highly Active Antiretroviral Therapy Initiated During Early Versus Advanced States of HIV Disease

2000 • 28 citations

Phenotypic Analysis of CD8+ T Lymphocytes in a Cohort of HIV Type 1-Infected Patients Treated with Saquinavir, Ritonavir, and Two Nucleoside Analogs for 1 Year, and Association with Plasma HIV Type 1 RNA

1999 • 23 citations

Prospective Study of CD8⁺Lymphocyte Activation in Relation to Viral Load in HIV-Infected Patients with >=400 CD4⁺Lymphocytes per Microliter

1999 • 20 citations

The Dominant Source of CD4+ and CD8+ T-Cell Activation in HIV Infection Is Antigenic Stimulation

2000 • 18 citations