Food motivated behavior of melanocortin-4 receptor knockout mice under a progressive ratio schedule

Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice

1997 • 2,992 citations

Clinical Spectrum of Obesity and Mutations in the Melanocortin 4 Receptor Gene

2003 • 1,665 citations

Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacy

1996 • 1,301 citations

Progressive Ratio as a Measure of Reward Strength

1961 • 1,108 citations

Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain.

1994 • 1,059 citations

Divergence of Melanocortin Pathways in the Control of Food Intake and Energy Expenditure

2005 • 1,053 citations

Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain

1994 • 703 citations

Multiple neural systems controlling food intake and body weight

2002 • 701 citations

Progressive-ratio schedules of drug delivery in the analysis of drug self-administration: a review

1998 • 401 citations

Binge Eating as a Major Phenotype of Melanocortin 4 Receptor Gene Mutations

2003 • 371 citations

PREFERENCE AND SWITCHING UNDER CONCURRENT SCHEDULING¹

1958 • 362 citations

A metabolic defect promotes obesity in mice lacking melanocortin-4 receptors

2000 • 360 citations

Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat

2001 • 332 citations

EFFECTS OF INCREMENT SIZE AND REINFORCER VOLUME ON PROGRESSIVE RATIO PERFORMANCE

1963 • 299 citations

Role of the melanocortin-4 receptor in metabolic rate and food intake in mice.

2000 • 240 citations

THE ECONOMICS OF THE LAW OF EFFECT

1986 • 200 citations

The Proopiomelanocortin System

1999 • 173 citations

Altered energy balance causes selective changes in melanocortin-4(MC4-R), but not melanocortin-3 (MC3-R), receptors in specific hypothalamic regions: further evidence that activation of MC4-R is a physiological inhibitor of feeding.

1999 • 144 citations

An Operant Conditioning Technique for Studying Feeding-Fasting Patterns in Normal and Obese Mice

1956 • 126 citations

Knockout Studies Defining Different Roles for Melanocortin Receptors in Energy Homeostasis

2003 • 106 citations

Effects of neuropeptide Y, insulin, 2-deoxyglucose, and food deprivation on food-motivated behavior

1995 • 85 citations

Attenuation of sucrose reinforcement in dopamine D₁ receptor deficient mice

2003 • 73 citations

The melanocortin receptor MCR4 controls fat consumption

2003 • 63 citations

Voluntary exercise delays monogenetic obesity and overcomes reproductive dysfunction of the melanocortin-4 receptor knockout mouse

2004 • 53 citations

State‐Dependent Modulation of Feeding Behavior by Proopiomelanocortin‐Derived β‐Endorphin

2003 • 38 citations

Meal patterns and foraging in melanocortin receptor knockout mice

2004 • 29 citations

Melanocortins and feeding behavior

2000 • 26 citations