Interaction of pristinamycin IA with P-glycoprotein in human intestinal epithelial cells

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

1987 • 2,788 citations

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

1989 • 2,127 citations

Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture

1983 • 1,765 citations

Pharmacology of drugs that alter multidrug resistance in cancer.

1990 • 970 citations

Epithelial Transport Of Drugs In Cell Culture. I: A Model For Studying The Passive Diffusion Of Drugs Over Intestinal Absorbtive (Caco-2) Cells

1990 • 820 citations

ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells.

1988 • 480 citations

Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators

1993 • 365 citations

Identification of the multidrug resistance-related P-glycoprotein as a cyclosporine binding protein.

1989 • 242 citations

The multidrug resistance and cystic fibrosis genes have complementary patterns of epithelial expression.

1992 • 190 citations

Azidopine noncompetitively interacts with vinblastine and cyclosporin A binding to P-glycoprotein in multidrug resistant cells.

1991 • 178 citations

Peptide transport by the multidrug resistance pump.

1992 • 152 citations

High lipophilicity decreases drug transport across intestinal epithelial cells.

1994 • 147 citations

Evidence for a Polarized Efflux System for Peptides in the Apical Membrane of Caco-2 Cells

1993 • 141 citations

Polarized transport of docetaxel and vinblastine mediated by P-glycoprotein in human intestinal epithelial cell monolayers

1994 • 134 citations

P-glycoprotein possesses A 1,4-dihydropyridine-selective drug acceptor site which is alloserically coupled to a vinca-alkaloid-selective binding site

1992 • 121 citations

Reduced cyclosporin accumulation in multidrug-resistant cells

1988 • 115 citations

Digoxin-cyclosporin A interaction: modulation of the multidrug transporter P-glycoprotein in the kidney.

1993 • 94 citations

Biochemical characterization of resistance to mitoxantrone and adriamycin in Caco-2 human colon adenocarcinoma cells: a possible role for glutathione S-transferases.

1992 • 89 citations

SDZ 280-446, a novel semi-synthetic cyclopeptolide: in vitro and in vivo circumvention of the P-glycoprotein-mediated tumour cell multidrug resistance

1992 • 48 citations

VIRGINIAMYGIN: NOMENCLATURE

1972 • 44 citations

HT29-18-C1 intestinal cells: A new model for studying the epithelial transport of drugs

1993 • 15 citations

Multidrug resistance during cancer chemotherapy — biotechnological solutions to a clinical problem

1993 • 12 citations

Rapid and transient induction of c-fos, c-myc and c-Ha-ras in rat liver following glycine administration

1988 • 6 citations