Direct labelling of myocardial ? 1-adrenoceptors

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

1959 • 3,948 citations

Differentiation of Receptor Systems activated by Sympathomimetic Amines

1967 • 2,054 citations

BMDP-77, Biomedical Computer Programs, P-Series

1979 • 797 citations

Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes.

1982 • 573 citations

ADENYLATE CYCLASE-COUPLED BETA-ADRENERGIC RECEPTORS: Structure and Mechanisms of Activation and Desensitization

1983 • 486 citations

The Pharmacology of a β2-Selective Adrenoceptor Antagonist (ICI 118,551)

1983 • 419 citations

Simultaneous determination of beta-1 and beta-2-adrenergic receptors in tissues containing both receptor subtypes.

1979 • 418 citations

beta-Adrenergic Receptor Subtypes: Properties, Distribution, and Regulation

1981 • 277 citations

The clinical importance of cardioselectivity and lipophilicity in beta blockers

1980 • 264 citations

Differentiated blockade of the chronotropic effects of various adrenergic stimuli in the cat heart

1972 • 246 citations

Quantitative resolution of beta-adrenergic receptor subtypes by selective ligand binding: application of a computerized model fitting technique.

1979 • 220 citations

The affinity of (?)-propranolol for ? 1- and ? 1-autoreceptors of human heart

1985 • 175 citations

Coexistence of beta1 and beta2 adrenoceptors in mammalian lung: evidence from direct binding studies.

1978 • 153 citations

Measurement of hydrophobicity, surface activity, local anaesthesia, and myocardial conduction velocity as quantitative parameters of the non-specific membrane affinity of nine ?-adrenergic blocking agents

1973 • 148 citations

Convenient apparatus for recording contractions of isolated heart muscle

1965 • 136 citations

Potentiation of the effects of isoprenaline and noradrenaline by hydrocortisone in cat heart muscle

1972 • 117 citations

Studies on Receptor-mediated Activation of Adenylyl Cyclases

1974 • 107 citations

Characterization of [3H](+/-)carazolol binding to beta-adrenergic receptors. Application to study of beta-adrenergic receptor subtypes in canine ventricular myocardium and lung.

1981 • 100 citations

Direct labelling of ? 2-adrenoceptors

1985 • 94 citations

Stimulant and blocking effects of optical isomers of pindolol on the sinoatrial node and trachea of guinea pig. Role of ?-adrenoceptor subtypes in the dissociation between blockade and stimulation

1984 • 77 citations

Adrenergic receptors in heart muscle: relations among factors influencing the sensitivity of the cat papillary muscle to catecholamines.

1970 • 74 citations

The effect of cocaine on the pacemaker of isolated guinea-pig atria.

1968 • 73 citations

Comparative assessment of?-adrenoceptor blocking agents as simple competitive antagonists in isolated heart muscle: Similarity of inotropic and chronotropic blocking potencies against isoproterenol

1980 • 64 citations

A model for the interaction of competitive antagonists with two receptor-subtypes characterized by a schild-plot with apparent slope unity

1983 • 57 citations

On spare ?-adrenoceptors for inotropic effects of catecholamines in kitten ventricle

1978 • 53 citations

Homogeneity of beta 2-adrenoceptors on rat erythrocytes and reticulocytes. A comparison with heterogeneous rat lung beta-adrenoceptors.

1981 • 52 citations

An initial characterization of human heart ?-adrenoceptors and their mediation of the positive inotropic effects of catecholamines

1982 • 41 citations

A novel analysis of concentration-dependence of partial agonism

1982 • 34 citations

On equilibrium dissociation constants for complexes of drug-receptor subtypes

1982 • 34 citations

Different steric characteristics of ?1- and ?2-adrenoceptors

1984 • 34 citations

Competitive and non-competitive interactions between specific ligands and beta-adrenoceptors in living cardiac cells

1982 • 33 citations

Improved evaluation of binding of ligands to membranes containing several receptor-subtypes

1985 • 28 citations

INHIBITION OF [³H]‐DIHYDROALPRENOLOL BINDING TO RAT CARDIAC MEMBRANES BY VARIOUS β‐BLOCKING AGENTS

1978 • 25 citations

Heart ß-Receptors: On the Functional Role of Heterogeneous Binding Sites

1983 • 22 citations

3H-(?)-Bupranolol, a new ?-adrenoceptor radioligand: Characterization of its binding to kitten heart ?-adrenoceptors

1981 • 20 citations

Evidence that (+)-bupranolol interacts directly with myocardial ?-adrenoceptors

1980 • 15 citations

Cultured heart cells as a model for ?-adrenoceptors in a heart pacemaker

1982 • 12 citations

Binding of (3H)dihydroalprenolol to beta adrenoceptors of cells isolated from adult rat heart

1978 • 12 citations