The affinity of (?)-propranolol for ? 1- and ? 1-autoreceptors of human heart

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

1959 • 3,948 citations

Differentiation of Receptor Systems activated by Sympathomimetic Amines

1967 • 2,054 citations

BMDP-77, Biomedical Computer Programs, P-Series

1979 • 797 citations

The Uptake and Storage of Noradrenaline in Sympathetic Nerves

1967 • 706 citations

Treatment of Hypertension with Propranolol

1969 • 426 citations

Human cardiac beta-adrenergic receptors: Subtype heterogeneity delineated by direct radioligand binding

1983 • 178 citations

Convenient apparatus for recording contractions of isolated heart muscle

1965 • 136 citations

Coexistence of beta 1- and beta 2-adrenoceptors in human right atrium. Direct identification by (+/-)-[125I]iodocyanopindolol binding.

1983 • 123 citations

Potentiation of the effects of isoprenaline and noradrenaline by hydrocortisone in cat heart muscle

1972 • 117 citations

α-adrenoceptor-mediated positive inotropic effect of phenylephrine in isolated human ventricular myocardium

1984 • 115 citations

Demonstration in human atrial preparations of ?-adrenoceptors mediating positive inotropic effects

1978 • 108 citations

Studies on Receptor-mediated Activation of Adenylyl Cyclases

1974 • 107 citations

β‐Adrenoceptors of the human myocardium: determination of β₁ and β₂ subtypes by radioligand binding

1983 • 102 citations

The uptake of isoprenaline and noradrenaline by the perfused rat heart.

1966 • 96 citations

Direct labelling of ? 2-adrenoceptors

1985 • 94 citations

Binding of iodinated beta adrenergic antagonists to proteins derived from rat heart.

1976 • 85 citations

Analysis of beta receptor drug interactions in isolated rabbit atrium, aorta, stomach and trachea.

1970 • 84 citations

Pharmacological characteristics of adrenergic receptors.

1970 • 77 citations

Adrenergic receptors in heart muscle: relations among factors influencing the sensitivity of the cat papillary muscle to catecholamines.

1970 • 74 citations

The cardiac beta-adrenergic receptor. Structural similarities of beta 1 and beta 2 receptor subtypes demonstrated by photoaffinity labeling.

1983 • 73 citations

The human heart beta-adrenergic receptors. I. Heterogeneity of the binding sites: presence of 50% beta 1- and 50% beta 2-adrenergic receptors.

1983 • 66 citations

Comparative assessment of?-adrenoceptor blocking agents as simple competitive antagonists in isolated heart muscle: Similarity of inotropic and chronotropic blocking potencies against isoproterenol

1980 • 64 citations

The human heart beta-adrenergic receptors. II. Coupling of beta 2-adrenergic receptors with the adenylate cyclase system.

1983 • 62 citations

On spare ?-adrenoceptors for inotropic effects of catecholamines in kitten ventricle

1978 • 53 citations

Direct labelling of myocardial ? 1-adrenoceptors

1985 • 45 citations

Heart β-Adrenoceptors

1978 • 42 citations

An initial characterization of human heart ?-adrenoceptors and their mediation of the positive inotropic effects of catecholamines

1982 • 41 citations

Prostaglandin E1 action on sinus pacemaker and adenylyl cyclase in kitten myocardium

1974 • 39 citations

?-Adrenergic receptors in guinea-pig myocardial tissue

1976 • 38 citations

Different steric characteristics of ?1- and ?2-adrenoceptors

1984 • 34 citations

CATECHOLAMINE UPTAKE BY ISOLATED CORONARY ARTERIES AND ATRIA OF THE KITTEN

1978 • 30 citations

Improved evaluation of binding of ligands to membranes containing several receptor-subtypes

1985 • 28 citations

Evidence from agonist and antagonist studies to suggest that the β1-adrenoceptors subserving the positive inotropic and chronotropic responses of the heart do not belong to two separate subgroups

1977 • 26 citations

A quantitative study of beta-adrenergic receptors in rabbit atria

1970 • 25 citations

Heart ß-Receptors: On the Functional Role of Heterogeneous Binding Sites

1983 • 22 citations

[Cardiac beta receptors--experimental aspects].

1983 • 20 citations

3H-(?)-Bupranolol, a new ?-adrenoceptor radioligand: Characterization of its binding to kitten heart ?-adrenoceptors

1981 • 20 citations

Effect of propranolol on mortality in patients with angina.

1976 • 19 citations

Effect of propranolol on mortality in patients with angina.

1976 • 15 citations

The adrenergic nerves of the normal and the hypertrophied heart: Biochemical, histochemical, electron-microscopic and morphometric studies

1978 • 13 citations

Demonstration of two different types of beta1-receptors in man (selective blockade of the positively inotropic and the positively chronotropic effect of isoproterenol).

1978 • 10 citations

ADRENERGIC TRANSMISSION

1971 • 7 citations