Interleukin-1α-converting enzyme (ICE) and related cell death genes ICErel-II and ICErel-III map to the same PAC clone at band 11q22.2-22.3

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

1992 • 2,495 citations

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme

1993 • 2,484 citations

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

1996 • 1,902 citations

Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock

1995 • 1,413 citations

A new bacteriophage P1–derived vector for the propagation of large human DNA fragments

1994 • 857 citations

Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

1994 • 843 citations

Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models

1995 • 604 citations

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

1996 • 580 citations

The Alzheimer's Aβ peptide induces neurodegeneration and apoptotic cell death in transgenic mice

1995 • 517 citations

Chromosome engineering in mice

1995 • 479 citations

Modes of DAPI banding and simultaneous in situ hybridization

1993 • 397 citations

Programmed cell death in Caenorhabditis elegans

1994 • 379 citations

Long-range disruption of gene expression by a selectable marker cassette

1996 • 377 citations

Molecular Cloning and Pro-apoptotic Activity of ICErelII and ICErelIII, Members of the ICE/CED-3 Family of Cysteine Proteases

1995 • 281 citations

ICE/CED3-like Proteases as Therapeutic Targets for the Control of Inappropriate Apoptosis

1996 • 267 citations

Cloning and Expression of Four Novel Isoforms of Human Interleukin-1β Converting Enzyme with Different Apoptotic Activities

1995 • 149 citations

If birds can fly, why can't we? Homeotic genes and evolution

1994 • 107 citations

Developmental regulation of human β-globin gene transcription: a switch of loyalties?

1993 • 100 citations

Molecular cloning of the murine IL-1 beta converting enzyme cDNA.

1992 • 65 citations

The Structure and Complete Nucleotide Sequence of the Murine Gene Encoding Interleukin-1β Converting Enzyme (ICE)

1994 • 62 citations

Molecular Characterization of the Gene for Human Interleukin-1β Converting Enzyme (IL1BC)

1994 • 45 citations

A Yeast Artificial Chromosome Contig andNotI Restriction Map That Spans the Tumor Suppressor Gene(s) Locus, 11q22.2–q23.3

1996 • 42 citations

Co-amplification of L1 line elements with localised low copy repeats in Giemsa dark bands: implications for genome organisation

1991 • 19 citations

Localization of the cell death genes CPP32 and Mch-2 to human Chromosome 4q

1997 • 13 citations