Increased monocyte cytokine production in association with systemic complications in acute pancreatitis

APACHE II-A Severity of Disease Classification System

1986 • 12,607 citations

APACHE II

1985 • 12,347 citations

A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF

1988 • 1,105 citations

Circulating Interleukin-1 and Tumor Necrosis Factor in Septic Shock and Experimental Endotoxin Fever

1990 • 765 citations

Prognostic Values of Tumor Necrosis Factor/Cachectin, Interleukin-l, Interferon- , and Interferon- in the Serum of Patients with Septic Shock

1990 • 555 citations

A single-centre double-blind trial of Trasylol therapy in primary acute pancreatitis

1978 • 535 citations

Prediction of outcome in acute pancreatitis: A comparative study of APACHE II, clinical assessment and multiple factor scoring systems

1990 • 483 citations

Phase I study of recombinant tumor necrosis factor in cancer patients.

1987 • 430 citations

Role of interleukin-6 in mediating the acute phase protein response and potential as an early means of severity assessment in acute pancreatitis.

1993 • 289 citations

Gabexate mesilate in human acute pancreatitis

1993 • 231 citations

Fatal pancreatitis, a consequence of excessive leukocyte stimulation?

1988 • 212 citations

Endotoxaemia and serum tumour necrosis factor as prognostic markers in severe acute pancreatitis.

1992 • 203 citations

Inhibition of lung inflammatory reactions in rats by an anti-human IL-8 antibody.

1993 • 183 citations

The role of cytokine mediators in septic shock.

1990 • 172 citations

Role of interleukin-6 in acute pancreatitis. Comparison with C-reactive protein and phospholipase A.

1992 • 162 citations

Down-regulation of tumor necrosis factor ? activity by acute ethanol treatment in human peripheral blood monocytes

1993 • 113 citations

Hemodynamic data pattern in patients with acute pancreatitis

1986 • 108 citations

Multicentre clinical trial of low volume fresh frozen plasma therapy in acute pancreatitis

1987 • 81 citations

Endotoxaemia and complement activation in acute pancreatitis in man.

1982 • 81 citations

A multicentre controlled clinical trial of high-volume fresh frozen plasma therapy in prognostically severe acute pancreatitis.

1991 • 75 citations

Alpha 2 macroglobulin state in acute pancreatitis. Raised values of alpha 2 macroglobulin-protease complexes in severe and mild attacks.

1991 • 60 citations

Experimental Pancreatitis in the Dog. Demonstration of Trypsin in Ascitic Fluid, Lymph and Plasma

1973 • 54 citations

Experimental acute pancreatitis in dogs. I. Hypotensive effect induced by pancreatic exudate.

1968 • 49 citations

Endotoxaemia and acute pancreatitis: correlation between the severity of the disease and the anti-enterobacterial common antigen antibody titre.

1984 • 49 citations

Hemodynamic Consequences of Severe Pancreatitis

1983 • 48 citations

Is fatal pancreatitis a consequence of excessive leukocyte stimulation? The role of tumor necrosis factor α

1991 • 48 citations

Death from acute pancreatitis. M.R.C. multicentre trial of glucagon and aprotinin.

1977 • 47 citations

Preservation of cytotoxic function during multi-cycle immunomagnetic cell separations of human NK cells using a new type of magnetic bead

1990 • 35 citations

Toxicity of Hemorrhagic Ascitic Fluid Associated With Hemorrhagic Pancreatitis

1982 • 29 citations

Preliminary studies on the interaction of TNFα and IFNγ with α2-macroglobulin

1992 • 28 citations

Treatment of malignant melanoma and renal cell carcinoma with recombinant human interleukin-2: analysis of cytokine levels in sera and culture supernatants

1992 • 28 citations

Effects of a somatostatin analogue (SMS 201-995) on hepatic and splenic reticulo-endothelial function in the rat

1985 • 25 citations

The effects of somatostatin and SMS 201-995 on experimentally-induced pancreatitis and endotoxaemia in rats and on monocyte activity in patients with cirrhosis and portal hypertension.

1986 • 21 citations