Interleukin-4 and Interleukin-13 Differentially Regulate Epithelial Chloride Secretion

Physiology of the Gastrointestinal Tract

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1987 • 1,948 citations

Cytokine signal transduction

1994 • 1,358 citations

Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist

1990 • 1,095 citations

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

1994 • 888 citations

lnterleukin-13 is a new human lymphokine regulating inflammatory and immune responses

1993 • 877 citations

Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers.

1989 • 761 citations

Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function.

1993 • 565 citations

Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction.

1993 • 457 citations

Regulation of intestinal epithelial cell growth by transforming growth factor type beta.

1989 • 341 citations

Expression and characterization of the cystic fibrosis transmembrane conductance regulator

1990 • 340 citations

Effects of growth factors on an intestinal epithelial cell line: Transforming growth factor β inhibits proliferation and stimulates differentiation

1987 • 305 citations

IFN-gamma modulation of epithelial barrier function. Time course, reversibility, and site of cytokine binding.

1993 • 246 citations

Intestinal immune responses in humans. Oral cholera vaccination induces strong intestinal antibody responses and interferon-gamma production and evokes local immunological memory.

1991 • 226 citations

Effect of tumor necrosis factor on epithelial tight junctions and transepithelial permeability.

1990 • 224 citations

Hepatocyte growth factor/scatter factor effects on epithelia. Regulation of intercellular junctions in transformed and nontransformed cell lines, basolateral polarization of c-met receptor in transformed and natural intestinal epithelia, and induction of rapid wound repair in a transformed model epithelium.

1994 • 209 citations

[24] Established intestinal cell lines as model systems for electrolyte transport studies

1990 • 188 citations

IL-4 directly modulates function of a model human intestinal epithelium.

1994 • 181 citations

Regulation of Ion Channels by ABC Transporters That Secrete ATP

1995 • 174 citations

Human intestinal epithelial cells express functional cytokine receptors sharing the common gamma c chain of the interleukin 2 receptor.

1995 • 174 citations

A simple assay for agonist-regulated Cl and K conductances in salt-secreting epithelial cells

1990 • 169 citations

Neutrophil migration across cultured intestinal epithelial monolayers is modulated by epithelial exposure to IFN-gamma in a highly polarized fashion.

1993 • 163 citations

Interferon-gamma induces a cell surface phenotype switch on T84 intestinal epithelial cells

1994 • 138 citations

Interferon-gamma downregulates CFTR gene expression in epithelial cells

1994 • 102 citations

Functional interleukin-2 receptors on intestinal epithelial cells.

1993 • 100 citations

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1993 • 86 citations

Characterization and Comparison of the Interleukin 13 Receptor with the Interleukin 4 Receptor on Several Cell Types

1995 • 79 citations

Gamma‐Interferon‐Mediated Down‐Regulation of Electrolyte Secretion by Intestinal Epithelial Cells: A Local Immune Mechanism?

1989 • 69 citations

Stimulation of the expression and the enzyme activity of aminopeptidase N/CD13 and dipeptidylpeptidase IV/CD26 on human renal cell carcinoma cells and renal tubular epithelial cells by T cell-derived cytokines, such as IL-4 and IL-13

1995 • 52 citations