Circumvention of pleiotropic drug resistance in subcutaneous tumours in vivo with verapamil and clomipramine

Expression of a multidrug-resistance gene in human tumors and tissues.

1987 • 1,547 citations

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.

1981 • 1,463 citations

Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.

1982 • 667 citations

Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients.

1987 • 425 citations

Detection of P-glycoprotein in ovarian cancer: a molecular marker associated with multidrug resistance.

1985 • 410 citations

Genetic and biochemical characterization of multidrug resistance

1985 • 405 citations

P-glycoprotein in human sarcoma: evidence for multidrug resistance.

1987 • 261 citations

DETECTION OF A MULTIDRUG RESISTANT PHENOTYPE IN ACUTE NON-LYMPHOBLASTIC LEUKAEMIA

1987 • 223 citations

Anthracycline resistance in P388 murine leukemia and its circumvention by calcium antagonists.

1985 • 149 citations

Tumour cell resistance to anthracyclines ? A review

1985 • 120 citations

Verapamil potentiation of VP-16-213 in acute lymphatic leukemia and reversal of pleiotropic drug resistance

1986 • 60 citations

Verapamil Reversal of Clinical Doxorubicin Resistance in Human Cancer A Wilshire Oncology Medical Group Pilot Phase I-II Study

1986 • 56 citations

Actinomycin D: drug concentrations and actions in mouse tissues and tumors.

1968 • 48 citations

Verapamil enhancement of antitumor effect of cis-diamminedichloroplatinum(II) in nude mouse-grown human neuroblastoma.

1987 • 41 citations

The effect of liposome (phospholipid vesicle) entrapment of actinomycin D and methotrexate on the in vivo treatment of sensitive and resistant solid murine tumours

1981 • 29 citations

Cross resistance between actinomycin-D, adriamycin and vincristine in a murine solid tumour in vivo

1980 • 29 citations

Verapamil potentiation of melphalan cytotoxicity and cellular uptake in murine fibrosarcoma and bone marrow

1985 • 23 citations

Effect of verapamil on doxorubicin activity and pharmacokinetics in mice bearing resistant and sensitive solid tumors

1988 • 20 citations

Human Tumour Xenografts in Anticancer Drug Development

1988 • 20 citations

Occurrence of a multidrug-resistant phenotype in human lung xenografts

1987 • 13 citations

Development of drug resistance in a human epidermoid lung carcinoma xenograft line

1988 • 7 citations