Lipid IVA inhibits synthesis and release of tumor necrosis factor induced by lipopolysaccharide in human whole blood ex vivo.

Detection of Circulating Tumor Necrosis Factor after Endotoxin Administration

1988 • 1,711 citations

Cachectin: More Than a Tumor Necrosis Factor

1987 • 1,457 citations

Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum.

1986 • 549 citations

Identification of a Lipid A Binding Site in the Acute Phase Reactant Lipopolysaccharide Binding Protein

1989 • 351 citations

Detoxification of Bacterial Lipopolysaccharides (Endotoxins) by a Human Neutrophil Enzyme

1986 • 278 citations

IL-1 induction-capacity of defined lipopolysaccharide partial structures.

1989 • 269 citations

Synthetic lipid A with endotoxic and related biological activities comparable to those of a natural lipid A from an Escherichia coli re-mutant

1985 • 228 citations

Endotoxic properties of chemically synthesized lipid A part structures. Comparison of synthetic lipid A precursor and synthetic analogues with biosynthetic lipid A precursor and free lipid A

1984 • 180 citations

Isolation and characterization of eight lipid A precursors from a 3-deoxy-D-manno-octylosonic acid-deficient mutant of Salmonella typhimurium.

1985 • 126 citations

Induction of human interleukin 1 by bacterial and synthetic lipid A

1986 • 120 citations

Lipid A binding sites in membranes of macrophage tumor cells.

1988 • 112 citations

Specific endotoxic lipopolysaccharide-binding proteins on murine splenocytes. II. Membrane localization and binding characteristics.

1988 • 111 citations

The biosynthesis of gram-negative endotoxin. Formation of lipid A disaccharides from monosaccharide precursors in extracts of Escherichia coli.

1984 • 104 citations

Deacylated lipopolysaccharide inhibits neutrophil adherence to endothelium induced by lipopolysaccharide in vitro.

1987 • 96 citations

Protection of mice against lethal endotoxemia by a lipid A precursor

1986 • 85 citations

Production of human tumor necrosis factor from whole blood ex vivo.

1989 • 82 citations

Structure-Activity Relationship of Lipid A: Comparison of Biological Activities of Natural and Synthetic Lipid A's with Different Fatty Acid Compositions1

1986 • 82 citations

Chemical Structure and Biologic Activity of Bacterial and Synthetic Lipid A

1987 • 80 citations

Expression of bcr and bcr-abl fusion transcripts in normal and leukemic cells.

1987 • 75 citations

Molecular requirements for B-lymphocyte activation by Escherichia coli lipopolysaccharide.

1983 • 63 citations

Specific binding of endotoxin to human monocytes and mouse macrophages: Serum requirement

1985 • 55 citations

Structural requirements of lipid A species in activation of clotting enzymes from the horseshoe crab, and the human complement cascade

1988 • 49 citations

A 28,000-dalton protein of normal mouse serum binds specifically to the inner core region of bacterial lipopolysaccharide

1985 • 42 citations

Immunobiological activities of synthetic lipid A analogs with low endotoxicity

1986 • 37 citations

Induction of kappa light chain synthesis in 70Z/3 B lymphoma cells by chemically defined lipid A precursors.

1988 • 34 citations

Comparison of the capacity of two lipid A precursor molecules to express the local Shwartzman phenomenon

1985 • 33 citations

Gram-negative Endotoxin: A Biologically Active Lipid

1988 • 33 citations

Endotoxic properties of synthetic pentaacyl lipid A precursor Ib and a structural isomer

1987 • 28 citations

Activation and inhibition of Limulus amebocyte lysate coagulation by chemically defined substructures of lipid A

1985 • 26 citations

Macrophages regulate the host response to bacterial lipopolysaccharides.

1989 • 18 citations

Expression of bcr And bcr-abl Fusion Transcripts in Normal and Leukemic Cells

1987 • 12 citations

Protection of Mice against Lethal Endotoxemia by a Lipid A Precursor

1986 • 7 citations