Serotonin2 agonist administration down-regulates rat brain serotonin2 receptors

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding

1980 • 840 citations

Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agents

1984 • 597 citations

Radioligand binding evidence implicates the brain 5-HT2 receptor as a site of action for LSD and phenylisopropylamine hallucinogens

1988 • 334 citations

Serotonin-stimulated phosphoinositide turnover: mediation by the S2 binding site in rat cerebral cortex but not in subcortical regions.

1985 • 197 citations

Regulation of serotonin-stimulated phosphoinositide hydrolysis: relation to the serotonin 5-HT-2 binding site

1986 • 190 citations

Serotonin receptor sensitivity after acute and chronic treatment with mianserin.

1982 • 188 citations

Selective 5ht-2 antagonists inhibit serotonin stimulated phosphatidylinositol metabolism in cerebral cortex

1984 • 179 citations

Antagonism of the effects of the hallucinogen dom and the purported 5-HT agonist quipazine by 5-HT2 antagonists

1983 • 178 citations

A drug discrimination analysis of lysergic acid diethylamide (LSD): in vivo agonist and antagonist effects of purported 5-hydroxytryptamine antagonists and of pirenperone, a LSD-antagonist.

1982 • 164 citations

Effects of lysergic acid diethylamide on the metabolism of brain 5-hydroxytryptamine

1967 • 161 citations

Down regulation of serotonin-S2 receptor sites in rat brain by chronic treatment with the serotonin-S2 antagonists: ritanserin and setoperone

1986 • 154 citations

Behavioral and 5-HT antagonist effects of ritanserin: A pure and selective antagonist of LSD discrimination in rat

1985 • 143 citations

5-HT1 and 5-HT2 binding properties of derivatives of the hallucinugen 1-(2,5-dimethoxyphenyl)-2-aminopropane (2,5-DMA)

1984 • 127 citations

Effect of chronic antidepressant treatment and subsequent withdrawal on [3H]-5-hydroxytryptamine and [3H]-spiperone binding in rat frontal cortex and serotonin receptor mediated behaviour

1983 • 126 citations

Neuropharmacology of serotonin

1986 • 116 citations

Effect of hallucinogens on spontaneous and sensory-evoked locus coeruleus unit activity in the rat: reversal by selective 5-HT2antagonists

1986 • 105 citations

5-HT1 and 5-HT2 binding characteristics of 1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane analogs

1986 • 103 citations

Biology of Serotonergic Transmission

1983 • 91 citations

Acute and chronic effects of serotonin (5HT) antagonists on serotonin binding sites

1983 • 77 citations

Behavioral and serotonin receptor properties of 4-substituted derivatives of the hallucinogen 1-(2,5-dimethoxyphenyl)-2-aminopropane

1982 • 71 citations

Discriminative stimulus properties of the serotonergic agent 1-(2, 5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)

1986 • 70 citations

[3H]DOB: A specific agonist radioligand for 5-HT2 serotonin receptors

1985 • 67 citations

Different effects of serotonin antagonists on 3H-mianserin and 3H-ketanserin recognition sites

1985 • 60 citations

Daily LSD administration selectively decreases serotonin2 receptor binding in rat brain

1985 • 57 citations

Adaptive changes in the 5-HT2 binding site after chronic administration of agonists and antagonists

1986 • 52 citations

Phenethylamine hallucinogens in the locus coeruleus: potency of action correlates with rank order of 5-HT2 binding affinity

1986 • 49 citations

[ ³ H]Lysergic Acid Diethylamide: Cellular Autoradiographic Localization in Rat Brain

1971 • 42 citations

Mechanistic studies on DOM as a discriminative stimulus

1985 • 39 citations

Binding to the serotonin 5-HT2 receptor by the enantiohers of 125I-DOI

1987 • 39 citations

Blockade of the behavioral effects of lysergic acid diethylamide, 2,5-dimethoxy-4-methylamphetamine, quipazine and lisuride by 5-hydroxytryptamine antagonists.

1983 • 34 citations

Autoradiographic localization of binding sites for 125I-DOI, a new psychotomimetic radioligand, in the rat brain

1987 • 31 citations

Effects of antidepressant drug combinations on cortical 5-HT2 receptors and wet-dog shakes in rats

1985 • 30 citations

Autoradiography of LSD and 2,5-dimethoxyphenylisopropylamine psychotomimetics demonstrates regional, specific cross-displacement in the rat brain

1987 • 27 citations

Serotonergic agonists stimulate inositol lipid metabolism in rabbit platelets

1985 • 26 citations

The 5HT2 antagonist pirenperone reverses disruption of FR-40 by hallucinogenic drugs

1985 • 25 citations

Differential antagonism by metergoline of the behavioral effects of indolealkylamine and phenethylamine hallucinogens in the rat.

1981 • 20 citations

Regional serotonin receptor studies: Chronic methysergide treatment induces a selective and dose-dependent decrease in serotonin-2 receptors in mouse cerebral cortex

1986 • 19 citations

Is waning of a 5-hydroxytryptamine (5-HT)-mediated syndrome due to 5-HT2 receptor down-regulation?

1985 • 9 citations

Disruption of operant behavior by hallucinogenic drugs.

1986 • 5 citations