Regulation of serotonin-stimulated phosphoinositide hydrolysis: relation to the serotonin 5-HT-2 binding site

REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN‐I

1966 • 5,429 citations

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

1959 • 3,948 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

1982 • 2,148 citations

Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding

1980 • 840 citations

Discrimination of Multiple [³H]5‐Hydroxytryptamine Binding Sites by the Neuroleptic Spiperone in Rat Brain

1981 • 629 citations

The binding of serotonergic ligands to the porcine choroid plexus: Characterization of a new type of serotonin recognition site

1984 • 598 citations

Characteristics of central 5-HT receptors and their adaptive changes following intracerebral 5,7-dihydroxytryptamine administration in the rat.

1978 • 336 citations

5,7‐Dihydroxytryptamine: improvement of its selectivity for serotonin neurons in the CNS by pretreatment with desipramine

1975 • 298 citations

Thin-layer chromatography of the phosphoinositides

1968 • 256 citations

Evidence that phospholipid turnover is the signal transducing system coupled to serotonin-S2 receptor sites.

1985 • 206 citations

Simultaneous multiple electrode liquid chromatographic—electrochemical assay for catecholamines, indoleamines and metabolites in brain tissue

1983 • 201 citations

5-Hydroxytryptamine-stimulated inositol phospholipid hydrolysis in rat cerebral cortex slices: pharmacological characterization and effects of antidepressants.

1985 • 198 citations

Serotonin-stimulated phosphoinositide turnover: mediation by the S2 binding site in rat cerebral cortex but not in subcortical regions.

1985 • 197 citations

Serotonin receptor sensitivity after acute and chronic treatment with mianserin.

1982 • 188 citations

Selective 5ht-2 antagonists inhibit serotonin stimulated phosphatidylinositol metabolism in cerebral cortex

1984 • 179 citations

Role of Serotonergic Input in the Regulation of the β-Adrenergic Receptor-Coupled Adenylate Cyclase System

1982 • 176 citations

[52] Extraction and purification of polyphosphoinositides

1981 • 168 citations

125I-lysergic acid diethylamide binds to a novel serotonergic site on rat choroid plexus epithelial cells

1985 • 159 citations

Separation and analysis of 32P-labeled phospholipids by a simple and rapid thin-layer chromatographic procedure and its application to cultured neuroblastoma cells

1977 • 158 citations

Aortic recognition sites for serotonin (5HT) are coupled to phospholipase C and modulate phosphatidylinositol turnover

1984 • 146 citations

Multiple serotonin receptors: Regional distribution and effect of raphe lesions

1981 • 105 citations

Serotonin receptors in hippocampus and frontal cortex

1980 • 89 citations

Monoamine oxidase inhibitors and serotonin uptake inhibitors: differential effects on [3H]serotonin binding sites in rat brain.

1980 • 82 citations

Agonist-induced desensitization of muscarinic receptor-mediated calcium efflux without concomitant desensitization of phosphoinositide hydrolysis.

1985 • 81 citations

Hyper- and hyposensitivity of central serotonin receptors: [3H]serotonin binding and functional studies in the rat

1980 • 78 citations

α1-adrenoceptor-mediated inositol phospholipid hydrolysis in rat cerebral cortex: Relationship between receptor occupancy and response and effects of denervation

1985 • 77 citations

Acute and chronic effects of serotonin (5HT) antagonists on serotonin binding sites

1983 • 77 citations

The role of central serotonergic mechanisms on head-twitch and backward locomotion induced by hallucinogenic drugs

1981 • 52 citations

Effects of chronic antidepressant treatment on serotonin receptor activity in mice

1983 • 52 citations

Microdetermination of phosphoinositides in a single extract

1985 • 46 citations

Accumulation of inositol phosphates in sympathetic ganglia. Effects of depolarization and of amine and peptide neurotransmitters

1985 • 44 citations

Subsensitivity of serotonin receptors after long-term treatment of rats with fluoxetine.

1981 • 38 citations

Biochemical characterization of serotonin stimulated phosphoinositide turnover

1986 • 37 citations

Noradrenergic and serotonergic input necessary for imipramine-induced changes in beta but not S2 receptor densities

1983 • 35 citations

Surgical Sympathetic Denervation Increases α₁Adrenoceptor‐Mediated Accumulation of myo‐Inositol Trisphosphate and Muscle Contraction in Rabbit Iris Dilator Smooth Muscle

1986 • 35 citations

Effects of reserpine, para-chlorophenylalanine, 5,6-dihydroxytryptamine and fludiazepam on the head twitches induced by 5-hydroxytryptamine or 5-methoxytryptamine in mice

1978 • 35 citations

Noradrenergic denervation increases α1-adrenoreceptor-mediated inositol-phosphate accumulation in the hippocampus

1984 • 33 citations

Denervation Supersensitivity of the Rat Pineal to Norepinephrine‐Stimulated [³H]Inositide Turnover Revealed by Lithium and a Convenient Procedure

1985 • 30 citations

Some quantitative uses of drug antagonists

1997 • 29 citations

The formation of [3H]inositol phosphates in human platelets by palmitoyl lysophosphatidic acid is blocked by indomethacin

1985 • 14 citations