Advances in Radioprotection through the Use of Combined Agent Regimens

International Journal of Radiation Biology

1959 • 1,730 citations

Burger's Medicinal chemistry

1980 • 709 citations

Radioprotectors and anticarcinogens

1983 • 613 citations

Journal of the national cancer institute

1993 • 411 citations

Interdependence of the radioprotective effects of human recombinant interleukin 1 alpha, tumor necrosis factor alpha, granulocyte colony-stimulating factor, and murine recombinant granulocyte-macrophage colony-stimulating factor.

1988 • 265 citations

Radiation sensitizers, their use in the clinical management of cancer

1980 • 259 citations

Induction of mitochondrial manganese superoxide dismutase by interleukin 1

1988 • 232 citations

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY, BIOLOGY, PHYSICS

2004 • 170 citations

Chemoprotection against Three Modes of Radiation Death in the Mouse

1969 • 143 citations

Cellular antioxidant defense mechanisms

1989 • 133 citations

Interaction of Cultured Mammalian Cells with WR-2721 and Its Thiol, WR-1065: Implications for Mechanisms of Radioprotection

1983 • 132 citations

Time-scale and nature of radiation-biological damage: Approaches to radiation protection and post-irradiation therapy

1982 • 115 citations

16, 16-Dimethyl Prostaglandin E 2 Induces Radioprotection in Murine Intestinal and Hematopoietic Stem Cells

1985 • 113 citations

The radioprotector WR1065 reduces radiation-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in V79 cells

1985 • 112 citations

Role of superoxide dismutase in modification of radiation injury.

1987 • 99 citations

16,16-Dimethyl Prostaglandin E 2 Increases Survival in Mice Following Irradiation

1987 • 84 citations

Protective effects of analogs of luteinizing hormone-releasing hormone against x-radiation-induced testicular damage in rats.

1987 • 77 citations

Radiation Protection of Murine Intestine by WR-2721, 16, 16-Dimethyl Prostaglandin E 2 , and the Combination of Both Agents

1987 • 71 citations

Clinical trials of WR-2721 with radiation therapy

1982 • 64 citations

Can WR-2721 be improved upon?

1988 • 63 citations

Some pharmacologic effects of WR-2721: their role in toxicity and radioprotection.

1973 • 61 citations

Modification of Radiosensitivity of Biological Systems

1978 • 60 citations

Clinical trials of WR-2721 prior to alkylating agent chemotherapy and radiotherapy

1988 • 58 citations

Effect of vitamin E on post irradiation death in mice

1978 • 53 citations

Behavioral Toxicity and Efficacy of WR-2721 as a Radioprotectant

1985 • 52 citations

From endotoxins to newer immunomodulators: survival-promoting effects of microbial polysaccharide complexes in irradiated animals

1988 • 51 citations

Combined modality radioprotection: The use of glucan and selenium with WR-2721

1990 • 51 citations

Radioprotection by antioxidant enzymes and enzyme mimetics

1988 • 50 citations

Interleukin-1 enhances survival of lethally irradiated mice treated with allogeneic bone marrow cells

1989 • 50 citations

Radioprotection of mouse skin by WR-2721: The critical influence of oxygen tension

1982 • 49 citations

The British journal of cancer

1986 • 49 citations

Protection against ionising radiation and synergism with thiols by zinc aspartate

1986 • 48 citations

Some Pharmacologic Effects of WR-2721: Their Role in Toxicity and Radioprotection

1973 • 46 citations

Role of cytokines in radioprotection

1988 • 45 citations

Selenium Pretreatment Enhances the Radioprotective Effect and Reduces the Lethal Toxicity of Wr-2721

1987 • 45 citations

Dose and time relationships of the radioprotector WR-2721 on locomotor activity in mice

1987 • 44 citations

Radiation protection in vivo by prostaglandins and related compounds of the arachidonic acid cascade

1988 • 44 citations

Treatment of Radiation Injuries

1990 • 40 citations

Morbidity and mortality reduction by supplemental vitamin A or beta-carotene in CBA mice given total-body gamma-radiation.

1984 • 38 citations

Postirradiation Glucan Administration Enhances the Radioprotective Effects of WR-2721

1989 • 37 citations

Leukotriene-Induced Radioprotection of Hematopoietic Stem Cells in Mice

1988 • 35 citations

Reduction of Short- and Long-Term Radiation Lethality by Mixtures of Chemical Protectors

1968 • 33 citations

A novel interaction of diethyldithiocarbamate with the glutathione/glutathione peroxidase system

1986 • 31 citations

Radioprotection by biological response modifiers alone and in combination with WR-2721

1988 • 28 citations

Polysaccharides Induce Radioprotection of Murine Hemopoietic Stem Cells and Increase the LD 50/30 Days

1986 • 26 citations

Radioprotection of mouse intestine by inhibitors of cyclic AMP phosphodiesterase

1979 • 25 citations

Radiation Protection by Exogenous Arachidonic Acid and Several Metabolites

1987 • 19 citations

Immunophysiology: The role of cells and cytokines in immunity and inflammation

1990 • 14 citations

Survey of newer biological response modifiers for possible use in radioprotection

1988 • 14 citations

Protection of mice against mixed fission neutron-gamma (n: gamma = 1:1) irradiation by WR-2721, 16,16-dimethyl PGE2, and the combination of both agents.

1988 • 13 citations

Behavioral radioprotection

1988 • 13 citations

Protection of Mice against Mixed Fission Neutron-g (n:g = 1:1) Irradiation by WR-2721, 16, 16-Dimethyl PGE 2 , and the Combination of Both Agents

1988 • 13 citations

Relative Biological Effectiveness Measurements Using Murine Lethality and Survival of Intestinal and Hematopoietic Stem Cells after Fermilab Neutrons Compared to JANUS Reactor Neutrons and 60 Co Gamma Rays

1984 • 10 citations

Bone marrow cell protection and modification of drug toxicity by combination of protectors

1988 • 10 citations

A Paradoxical Role for Eicosanoids: Radioprotectants and Radiosensitizers

1987 • 8 citations

SURVIVAL-PROMOTING EFFECTS OF ENDOTOXIN IN MICE, DOGS, AND SHEEP.

1970 • 4 citations