From endotoxins to newer immunomodulators: survival-promoting effects of microbial polysaccharide complexes in irradiated animals

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells¹

2010 • 4,125 citations

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells

1961 • 3,579 citations

log-normal distribution

2008 • 1,850 citations

Cachectin: More Than a Tumor Necrosis Factor

1987 • 1,457 citations

The Lognormal Distribution.

1957 • 515 citations

Interleukin 1 is a radioprotector.

1986 • 386 citations

The Physiological Disturbances Produced by Endotoxins

1954 • 284 citations

Properdin System and Immunity: II. Interaction of the Properdin System with Polysaccharides

1955 • 268 citations

Increased Survival in Irradiated Animals Treated With Bacterial Endotoxins

1957 • 139 citations

Experimental Hematology Today 1978

1978 • 123 citations

The organization of hemopoietic tissue as inferred from the effects of 5-fluorouracil.

1982 • 122 citations

16, 16-Dimethyl Prostaglandin E 2 Induces Radioprotection in Murine Intestinal and Hematopoietic Stem Cells

1985 • 113 citations

Glucan: Mechanisms Involved in Its “Radioprotective” Effect

1987 • 99 citations

The effect of Salm. typhi and its endotoxin on the phagocytic activity of the reticuloendothelial system in mice.

1955 • 89 citations

Hematopoietic Recovery Induced by Bacterial Endotoxin in Irradiated Mice

1958 • 85 citations

Rapidly induced changes in the level of non-specific immunity in laboratory animals.

1956 • 77 citations

INCREASE IN RESISTANCE FOLLOWING ADMINISTRATION OF BACTERIAL LIPOPOLYSACCHARIDES

1956 • 61 citations

Endotoxin Protection and Colony-Forming Units

1967 • 60 citations

Activation of the reticulo‐endothelial cells of the mouse liver by bacterial lipopolysaccharide

1959 • 54 citations

Modification of the X-irradiation syndrome by lycopene*1

1959 • 51 citations

Stimulated hemopoiesis and enhanced survival following glucan treatment in sublethally and lethally irradiated mice

1985 • 51 citations

STUDIES ON SUSCEPTIBILITY TO INFECTION FOLLOWING IONIZING RADIATION

1954 • 47 citations

Biological activities of endotoxins detoxified by alkylation

1975 • 46 citations

THE PROTECTIVE EFFECT OF GRANULOCYTES IN RADIATION INJURY

1955 • 46 citations

Effect of Microbial Antigens on Irradiation Mortality in Mice.

1959 • 44 citations

Effect of Ionizing Radiation on Resistance and Infection

1955 • 41 citations

Resistance to Experimental Infection and Mobilization of Granulocytes in Irradiated Mice Treated With Bacterial Endotoxin

1958 • 41 citations

STUDIES ON SUSCEPTIBILITY TO INFECTION FOLLOWING IONIZING RADIATION

1960 • 39 citations

The Radioprotective Effect of Bacterial Endotoxin

1983 • 39 citations

Evaluation of the mechanism of glucan-induced stimulation of the reticuloendothelial system.

1970 • 38 citations

THE PROPERDIN SYSTEM IN RELATION TO FATAL BACTEREMIA FOLLOWING TOTAL‐BODY IRRADIATION OF LABORATORY ANIMALS

1956 • 37 citations

Effect of Piromen on Survival of Irradiated Mice.

1953 • 37 citations

Comparative effects of soluble and particulate glucans on survival in irradiated mice.

1986 • 36 citations

Modulation of myelopoiesis in vivo by synthetic adjuvant-active muramyl peptides: induction of colony-stimulating activity and stimulation of stem cell proliferation

1983 • 33 citations

Granulocyte release by endotoxin in normal and irradiated mice

1961 • 30 citations

Resistance to whole-body X-irradiation in rats made tolerant to bacterial endotoxins

1959 • 28 citations

Radioprotection by biological response modifiers alone and in combination with WR-2721

1988 • 28 citations

Protective Effects of Interferon in Mice Previously Exposed to Lethal Irradiation

1980 • 26 citations

Stimulatory effect of N-acetyl Muramyl dipeptide in vivo: proliferation of bone marrow progenitor cells in mice

1982 • 26 citations

Polysaccharides Induce Radioprotection of Murine Hemopoietic Stem Cells and Increase the LD 50/30 Days

1986 • 26 citations

Radioprotective effect of reticuloendothelial system blockade in mice

1970 • 23 citations

Colony-forming units and survival of irradiated mice treated with AET or endotoxin.

1969 • 22 citations

Effects of BCG and Corynebacterium Parvum on the haemopoietic precursor cells in continuously irradiated mice: Possible mechanisms of action in immunotherapy

1977 • 22 citations

Glucan-induced enhancement of hemopoietic recovery in gamma-irradiated mice

1982 • 21 citations

In Search of the Active Sites in Endotoxins

1983 • 21 citations

Repopulation of Colony-forming Units in Mice

1967 • 21 citations

Dose Rate Studies with Fission Spectrum Neutrons

1976 • 20 citations

Effect of an Antibiotic Regime on Monkeys Exposed to Total-Body Irradiation

1964 • 19 citations

Radioprotective Properties of Detoxified Lipid A from Salmonella minnesota R595

1986 • 18 citations

The Effect of Pseudomonas Pyrogen on Survival of Irradiated Mice

1961 • 17 citations

Effect of Parenteral Injections of Particulate Matter on Survival of X-Irradiated Animals

1955 • 16 citations

Effect of LPS on Nonspecific Resistance to Bacterial Infections

1983 • 16 citations

Influence of Pre- and Post-X-Irradiation Zymosan Administration on Reticuloendothelial Function

1962 • 15 citations

The Effect of Proteus morganii Endotoxin on Radiation Mortality in Mice

1960 • 15 citations

Analysis of interleukin 1 mediated radioprotection.

1986 • 14 citations

Passive protection against X-irradiation with serum from zymosan-primed and endotoxin-injected mice.

1981 • 13 citations

Effect of Pyrogen on Phagocytic Digestion and Survival of X-Irradiated Mice

1958 • 13 citations

Protective and Therapeutic Effects of Bacterial Polysaccharides in Irradiation Injury in Mice

1959 • 12 citations

Colony-Forming Units and Survival of Irradiated Mice Treated with AET or Endotoxin

1969 • 12 citations

Effects of various treatments of CFU-S seeding efficiency in mice.

1984 • 11 citations

Radioprotection by polysaccharides

1988 • 11 citations

Decreased Radiation Mortality in Dogs treated with Typhoid–Paratyphoid Vaccine

1966 • 10 citations

Lodging of CFU(S) under various circumstances in bone marrow, spleen and liver.

1980 • 10 citations

Relative Biological Effectiveness Measurements Using Murine Lethality and Survival of Intestinal and Hematopoietic Stem Cells after Fermilab Neutrons Compared to JANUS Reactor Neutrons and 60 Co Gamma Rays

1984 • 10 citations

Beneficial effects of endotoxins

1984 • 9 citations

Early Radiation Mortality and Recovery in Large Animals and Primates

1984 • 9 citations

Radioprotection in Total-body Irradiated Primates

1966 • 9 citations

KINETICS OF HAEMOPOIETIC RECOVERY IN ENDOTOXIN‐TREATED MICE

1976 • 8 citations

Radioprotective and haemopoietic effects of some lipopolysaccharides from Rhodospirillaceae species in mice

1981 • 8 citations

Increased Survival of Irradiated Dogs Given Typhoid Vaccine before or after Irradiation

1968 • 7 citations

Enhancement of macrophage colony-stimulating factor in mice by carbon particle

1982 • 7 citations

Effect of bacterial lipopolysaccharide on proliferation of CFU-S.

1978 • 7 citations

Altered Split-Dose Recovery in Mice Irradiated under Hypoxic Conditions

1969 • 6 citations

Postirradiation Leukocyte Patterns in Mice and Dogs Treated with Endotoxin

1968 • 6 citations

Altered split-dose recovery in mice irradiated under hypoxic conditions.

1969 • 6 citations

Alterations Induced in Murine Hemopoietic Stem Cells Following a Single Injection of Corynebacterium parvum

1979 • 5 citations

Granulocytic recovery in the polycythemic dog treated with endotoxin postirradiation.

1973 • 5 citations

TREATMENT OF POST‐IRRADIATION INFECTIONS IN MICE

1956 • 5 citations

Treatment of post-irradiation infections in mice. I. The effect of streptomycin and myelopoietic-stimulating substances.

1956 • 5 citations

Effects of whole body irradiation in mice treated with C. parvum

1979 • 5 citations

Granulocytic Recovery in the Polycythemic Dog Treated with Endotoxin Postirradiation

1973 • 5 citations

[Bacterial lipopolysaccharides and their components as radiation-resistance increasing substances].

1971 • 4 citations

SURVIVAL-PROMOTING EFFECTS OF ENDOTOXIN IN MICE, DOGS, AND SHEEP.

1970 • 4 citations

ACUTE RADIATION EFFECTS ON STEADY STATE CELL POPULATIONS

1966 • 3 citations

Haemopoietic recovery during radiation disease: Comments on combined-injuries

1981 • 3 citations

A Staining Technique for Spleen Nodules A Comparison of D 0 � s

1969 • 2 citations

Radiation-protection and recovery from radiation injury in endotoxin-treated mice: Hematopoietic recovery and sensitivity to a second radiation exposure. USNRDL-TR-1023.

1966 • 2 citations