Inhibition of Human Telomerase by a G-Quadruplex-Interactive Compound

Telomeres shorten during ageing of human fibroblasts

1990 • 5,530 citations

Structure and function of telomeres

1991 • 3,524 citations

The RNA Component of Human Telomerase

1995 • 2,243 citations

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

1992 • 2,096 citations

Inhibition of telomerase by G-quartet DMA structures

1991 • 1,086 citations

Correlating telomerase activity levels with human neuroblastoma outcomes

1995 • 631 citations

The Three-Dimensional Crystal Structure of the Catalytic Core of Cellobiohydrolase I from Trichoderma reesei

1994 • 626 citations

Crystal structure of four-stranded Oxytricha telomeric DNA

1992 • 556 citations

The High-Resolution Crystal Structure of a Parallel-Stranded Guanine Tetraplex

1994 • 483 citations

Telomerase Activity in Small-Cell and Non-Small-Cell Lung Cancers

1995 • 447 citations

Inhibition of human telomerase activity by peptide nucleic acids

1996 • 342 citations

Human Lung Carcinogen--DNA Adduct Levels Mediated by Genetic Polymorphisms In Vivo

1995 • 194 citations

Telomeric repeat from T. thermophila cross hybridizes with human telomeres

1988 • 190 citations

Tetrahymena telomerase catalyzes nucleolytic cleavage and nonprocessive elongation.

1993 • 157 citations

Assembly of Transcriptionally Active RNA Polymerase I Initiation Factor SL1 from Recombinant Subunits

1994 • 148 citations

Liquid-like movements in crystalline insulin

1988 • 129 citations

Inadequacy of effective CO2 as a proxy in simulating the greenhouse effect of other radiatively active gases

1991 • 121 citations

Anthracene-9,10-diones as potential anticancer agents. Synthesis, DNA-binding, and biological studies on a series of 2,6-disubstituted derivatives

1992 • 87 citations

Do telomerase antagonists represent a novel anti-cancer strategy?

1996 • 63 citations

Synthesis, molecular modeling, DNA binding, and antitumor properties of some substituted amidoanthraquinones

1988 • 61 citations

Syntheses, resolution, and structure-activity relationships of potent acetylcholinesterase inhibitors: 8-carbaphysostigmine analogs

1992 • 49 citations