Cloning and chromosomal localization of the human TRK-B tyrosine kinase receptor gene (NTRK2)

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

The scanning model for translation: an update.

1989 • 3,525 citations

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

Functions of the neurotrophins during nervous system development: What the knockouts are teaching us

1994 • 1,431 citations

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.

1990 • 944 citations

trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors.

1991 • 785 citations

The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain

1990 • 748 citations

Neurotrophin receptors: A window into neuronal differentiation

1992 • 704 citations

Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death

1993 • 670 citations

trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

1989 • 604 citations

Molecular and biochemical characterization of the human trk proto-oncogene.

1989 • 600 citations

Trk receptors use redundant signal transduction pathways involving SHC and PLC-γ1 to mediate NGF responses

1994 • 538 citations

Expression and function of TRK-B and BDNF in human neuroblastomas.

1994 • 423 citations

Location of gene for Gorlin syndrome

1992 • 393 citations

Expression of the tyrosine kinase receptor gene trkB is confined to the murine embryonic and adult nervous system

1990 • 375 citations

Tyrosine 785 is a major determinant of Trk--substrate interaction.

1993 • 184 citations

The trk family of tyrosine protein kinase receptors

1991 • 170 citations

Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death

1993 • 164 citations

Insulin stimulation of phosphatidylinositol 3-kinase activity maps to insulin receptor regions required for endogenous substrate phosphorylation.

1992 • 148 citations

Localization of the gene for familial dysautonomia on chromosome 9 and definition of DNA markers for genetic diagnosis

1993 • 144 citations

A Trk nerve growth factor (NGF) receptor point mutation affecting interaction with phospholipase C-gamma 1 abolishes NGF-promoted peripherin induction but not neurite outgrowth.

1994 • 132 citations

Multiple self–healing squamous epitheliomata (ESS1) mapped to chromosome 9q22–q31 in families with common ancestry

1993 • 90 citations

Human trk Oncogenes Activated by Point Mutation, In-Frame Deletion, and Duplication of the Tyrosine Kinase Domain

1990 • 73 citations

Human trk oncogenes activated by point mutation, in-frame deletion, and duplication of the tyrosine kinase domain.

1990 • 54 citations

The Friedreich ataxia gene is assigned to chromosome 9q13-q21 by mapping of tightly linked markers and shows linkage disequilibrium with D9S15.

1990 • 54 citations

Molecular Characterization of the Human trk Oncogene

1986 • 50 citations

Cloning of a non-catalytic form of human trkBand distribution of messenger RNA for trkB in human brain

1994 • 46 citations

Human TRK proto-oncogene maps to chromosome 1q32-q41.

1990 • 39 citations

Frequent generation of oncogenes by in vitro recombination of TRK protooncogene sequences.

1988 • 37 citations