A synthetic peptide inhibitor of human immunodeficiency virus replication: correlation between solution structure and viral inhibition.

Computed circular dichroism spectra for the evaluation of protein conformation

1969 • 3,654 citations

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

1984 • 3,566 citations

Spectroscopic Determination of Tryptophan and Tyrosine in Proteins^*

1967 • 3,423 citations

Determination of the helix and β form of proteins in aqueous solution by circular dichroism

1974 • 2,040 citations

Evidence That the Leucine Zipper Is a Coiled Coil

1989 • 869 citations

In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity

1988 • 754 citations

Molecular Targets for AIDS Therapy

1990 • 736 citations

Dissociation of gp120 from HIV-1 Virions Induced by Soluble CD4

1990 • 598 citations

High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolates.

1990 • 461 citations

Isolation and properties of Moloney murine leukemia virus mutants: use of a rapid assay for release of virion reverse transcriptase

1981 • 439 citations

A General Model for the Transmembrane Proteins of HIV and Other Retroviruses

1989 • 375 citations

Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gp120 and the surface antigen CD4: role of carbohydrate in binding and cell fusion.

1987 • 220 citations

Human immunodeficiency virus type 1 activates the classical pathway of complement by direct C1 binding through specific sites in the transmembrane glycoprotein gp41.

1991 • 207 citations

Human retroviruses and aids, 1992

1992 • 119 citations

Presence of antibodies to a putatively immunosuppressive part of human immunodeficiency virus (HIV) envelope glycoprotein gp41 is strongly associated with health among HIV-positive subjects.

1988 • 105 citations

The site of an immune-selected point mutation in the transmembrane protein of human immunodeficiency virus type 1 does not constitute the neutralization epitope

1990 • 75 citations

Morphometric Analysis of Recombinant Soluble CD4-Mediated Release of the Envelope Glycoprotein gp120 from HIV-1

1990 • 72 citations

Characterization of a putative cellular receptor for HIV-1 transmembrane glycoprotein using synthetic peptides

1990 • 69 citations

Human retrovirus-related synthetic peptides inhibit T lymphocyte proliferation

1988 • 59 citations

Mapping the anatomy of the immunodominant domain of the human immunodeficiency virus gp41 transmembrane protein: peptide conformation analysis using monoclonal antibodies and proton nuclear magnetic resonance spectroscopy

1991 • 52 citations

Inhibition of protein kinase C and anti-CD3-induced Ca2+ influx in Jurkat T cells by a synthetic peptide with sequence identity to HIV-1 gp41.

1990 • 46 citations

Antibodies to a putative HIV gp41 immunosuppressive peptide, pHIVIS (583–599), do not correlate significantly with outcome in HIV infection

1990 • 17 citations