Kinetic Analysis of [¹¹C]McN5652: A Serotonin Transporter Radioligand

An Algorithm for Least-Squares Estimation of Nonlinear Parameters

1963 • 29,357 citations

Numerical Recipes, The Art of Scientific Computing

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Numerical recipes: the art of scientific computing

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A Technique for the Numerical Solution of Certain Integral Equations of the First Kind

1962 • 2,001 citations

A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography

1984 • 959 citations

REGULARIZATION OF INCORRECTLY POSED PROBLEMS

1963 • 890 citations

Cloning and expression of a functional serotonin transporter from rat brain

1991 • 822 citations

Equations for Measuring Blood Flow by External Monitoring of Radioisotopes

1965 • 786 citations

Measurement of Radiotracer Concentration in Brain Gray Matter Using Positron Emission Tomography: MRI-Based Correction for Partial Volume Effects

1992 • 712 citations

Tracer kinetic methods in medical physiology

1979 • 508 citations

Spectral Analysis of Dynamic PET Studies

1993 • 474 citations

The application of numerical filtering to the solution of integral equations encountered in indirect sensing measurements

1965 • 363 citations

Compartmental Modeling and Tracer Kinetics

1983 • 356 citations

Multiexponential, multicompartmental, and noncompartmental modeling. II. Data analysis and statistical considerations

1984 • 345 citations

Presynaptic monoaminergic vesicles in Parkinson's disease and normal aging

1996 • 312 citations

Principles of Nuclear Medicine

1976 • 272 citations

Multiple regression for physiological data analysis: the problem of multicollinearity

1985 • 271 citations

Principles of Nuclear Medicine

1996 • 260 citations

Positron emission tomography imaging of serotonin transporters in the human brain using [¹¹C](+)McN5652

1995 • 175 citations

Regional and subcellular localization in human brain of [3H]paroxetine binding, a marker of serotonin uptake sites

1988 • 171 citations

Multiexponential, multicompartmental, and noncompartmental modeling. I. Methodological limitations and physiological interpretations

1984 • 120 citations

Serotoninergic terminal transporters are differentially affected in Parkinson's disease and progressive supranuclear palsy: An autoradiographic study with [3H]citalopram

1993 • 113 citations

[11C](+)McN5652 as a radiotracer for imaging serotonin uptake sites with pet

1993 • 108 citations

Analysis of [^C-11]Alpha-Methyl-Tryptophan Kinetics for the Estimation of Serotonin Synthesis RateIn Vivo

1997 • 104 citations

A PET radiotracer for studying serotonin uptake sites: carbon-11-McN-5652Z.

1993 • 103 citations

Kinetic Evaluation of [¹¹C]Dihydrotetrabenazine by Dynamic PET: Measurement of Vesicular Monoamine Transporter

1996 • 100 citations

Monthly publication in 1986

1985 • 100 citations

Narcolepsy

1990 • 98 citations

Nuclear Medicine: Diagnosis and Therapy

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The inverse problem of radiography

1970 • 85 citations

A Weighted Least-Squares Technique for the Analysis of Kinetic Data and Its Application to the Study of Renal ¹³³ Xenon Washout in Dogs and Man

1973 • 80 citations

Experimental design optimisation: theory and application to estimation of receptor model parameters using dynamic positron emission tomography

1989 • 78 citations

McN-5652: a highly potent inhibitor of serotonin uptake.

1988 • 77 citations

Positron Emission Tomography of 5-HT Transporter Sites in the Baboon Brain with [¹¹C]McN5652

1995 • 72 citations

[¹¹C]Tropanyl Benzilate—Binding to Muscarinic Cholinergic Receptors: Methodology and Kinetic Modeling Alternatives

1994 • 72 citations

Pyrroloisoquinoline antidepressants. Potent, enantioselective inhibition of tetrabenazine-induced ptosis and neuronal uptake of norepinephrine, dopamine, and serotonin

1984 • 46 citations

Synthesis of a radiotracer for studying serotonin uptake sites with positron emission tomography: [¹¹C]McN‐5652‐Z

1992 • 45 citations

Deconvolution of linear systems by constrained regression and its relationship to the Wiener theory

1972 • 43 citations

Validation of the transporter ligand cyanoimipramine as a marker of serotonin innervation density in brain.

1994 • 37 citations

Evaluation of three transporter ligands as quantitative markers of serotonin innervation density in rat brain

1995 • 29 citations

Regional distribution of serotonergic pre‐ and postsynaptic markers in human brain

1989 • 24 citations

Model identification and estimation of organ-function parameters using radioactive tracers and the impulse-response function

1985 • 20 citations

Effects off pyrroloisoquinoline enantiomers ((+)- and (-)-McN-5652-Z) on behavioral and pharmacological serotonergic mechanisms in rats

1991 • 18 citations

Noncompartmental and compartmental modeling of the kinetics of carbon‐11 labeled pyrilamine in the human brain

1993 • 18 citations

Kinetic Evaluation of Positron-Emitting Muscarinic Receptor Ligands Employing Direct Intracarotid Injection

1996 • 14 citations

Fenfluramine-induced loss of serotonin transporters in baboon brain visualized with PET

1996 • 13 citations

Effects of statistical noise and digital filtering on the parameters calculated from the impulse response function

1987 • 5 citations