An intact NF-κB signaling pathway is required for maintenance of mature B cell subsets

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

NF-κB: Ten Years After

1996 • 3,008 citations

NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation

1998 • 2,698 citations

Clonal selection and learning in the antibody system

1996 • 1,710 citations

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow.

1991 • 1,622 citations

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.

1995 • 1,296 citations

Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses

1995 • 1,184 citations

In Vivo Ablation of Surface Immunoglobulin on Mature B Cells by Inducible Gene Targeting Results in Rapid Cell Death

1997 • 1,091 citations

Requirement for NF-κB in osteoclast and B-cell development

1997 • 994 citations

IMF-κB and Rel: Participants in a Multiform Transcriptional Regulatory System

1993 • 967 citations

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control

1997 • 875 citations

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression.

1995 • 740 citations

Defective B cell development and function in Btk-deficient mice

1995 • 729 citations

Coupling of a Signal Response Domain in IκBα to Multiple Pathways for NF-κB Activation

1995 • 706 citations

Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells.

1996 • 604 citations

Different Nuclear Signals Are Activated by the B Cell Receptor during Positive Versus Negative Signaling

1997 • 383 citations

The v-rel oncogene encodes a κB enhancer binding protein that inhibits NF-κB function

1990 • 325 citations

NF-κB RelA-deficient Lymphocytes: Normal Development of T Cells and B Cells, Impaired Production of IgA and IgG1 and Reduced Proliferative Responses

1997 • 296 citations

B-cell-specif ic coactivator OBF-1/OCA-B/Bob1 required for immune response and germinal centre formation

1996 • 284 citations

Sequential Induction of NF-κB/Rel Family Proteins during B-Cell Terminal Differentiation

1994 • 275 citations

Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival.

1993 • 265 citations

Perturbation of the T Lymphocyte Lineage In Transgenic Mice Expressing a Constitutive Repressor of Nuclear Factor (NF)-κB

1997 • 259 citations

I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding.

1992 • 252 citations

B Lymphocytes Differentially Use the Rel and Nuclear Factor κB1 (NF-κB1) Transcription Factors to Regulate Cell Cycle Progression and Apoptosis in Quiescent and Mitogen-activated Cells

1998 • 250 citations

Failure of Lymphopoiesis after Adoptive Transfer of NF-κB–Deficient Fetal Liver Cells

1997 • 193 citations

Inhibition of NF-κB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis

1998 • 164 citations

Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiation.

1994 • 137 citations

Novel IκBα Proteolytic Pathway in WEHI231 Immature B Cells

1998 • 120 citations

Complex pattern of immunoglobulin mu gene expression in normal and transgenic mice: nonoverlapping regulatory sequences govern distinct tissue specificities.

1991 • 99 citations

IgH enhancer-mediated deregulation of N-myc gene expression in transgenic mice: generation of lymphoid neoplasias that lack c-myc expression.

1989 • 97 citations

In Vivo Occupancy of the κ Light Chain Enhancers in Primary Pro- and Pre-B Cells: A Model for κ Locus Activation

1997 • 86 citations

Differences in DNA sequence specificity among MHC class II X box binding proteins.

1989 • 73 citations

Corepression of RelA and c-Rel Inhibits Immunoglobulin κ Gene Transcription and Rearrangement in Precursor B Lymphocytes

1996 • 70 citations

Transcription Factor NF-κB Regulates Inducible Oct-2 Gene Expression in Precursor B Lymphocytes

1997 • 31 citations