Analysis of point mutations in murine c‐Ha‐ras of skin tumors initiated with dibenz[a,j]anthracene and derivatives

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

ras GENES

1987 • 3,818 citations

Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis

1986 • 865 citations

Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats

1985 • 829 citations

Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations

1983 • 719 citations

The Action of Oncogenes in the Cytoplasm and Nucleus

1985 • 708 citations

Polynuclear Aromatic Hydrocarbons

2007 • 624 citations

Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas

1984 • 550 citations

Oncogene Activation in Chemical Carcinogenesis

1988 • 383 citations

Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression.

1990 • 270 citations

Activating mutations of the c-Ha-ras protooncogene in chemically induced hepatomas of the male B6C3 F1 mouse.

1986 • 250 citations

Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons.

1986 • 235 citations

The relationship between carcinogenicity and mutagenicity of some polynuclear hydrocarbons

1978 • 127 citations

Reaction of 7-bromomethylbenz[a]anthracene with nucleic acids, polynucleotides, and nucleosides

1971 • 122 citations

Oncogene activation and tumor progression

1984 • 119 citations

Mutational activation of oncogenes in animal model systems of carcinogenesis (MTR 07217)

1987 • 115 citations

Transforming ras oncogenes and multistage carcinogenesis

1985 • 109 citations

The Relation between Carcinogenic Activity and the Physical and Chemical Properties of Angular Benzacridines

1956 • 91 citations

Foreign Compound Metabolism

1985 • 90 citations

Chemical Carcinogenesis

1983 • 84 citations

The Bay Region Theory of Polycyclic Aromatic Hydrocarbon Carcinogenesis

1985 • 62 citations

Elevated expression and point mutation of the Ha-ras proto-oncogene in mouse skin tumors promoted by benzoyl peroxide and other promoting agents

1987 • 61 citations

Structure and activity in chemical carcinogenesis. Comparison of the reactions of 7-bromomethylbenz[a]anthracene and 7-bromomethyl-12-methylbenz[a]anthracene with deoxyribonucleic acid in bitro

1973 • 56 citations

Enhancement of the skin tumor-initiating activity of polycyclic aromatic hydrocarbons by methyl-substitution at non-benzo ‘bay-region’ positions

1983 • 46 citations

Structures of covalent nucleoside adducts formed from adenine, guanine, and cytosine bases of DNA and the optically active bay-region 3,4-diol 1,2-epoxides of dibenz[a,j]anthracene

1989 • 36 citations

Characterization of skin tumor promotion and progression by chrysarobin in SENCAR mice.

1987 • 36 citations

Structure-Activity Relationships Among Some Polynuclear Hydrocarbons and Their Hydrogenated Derivatives<xref ref-type="fn" rid="FN2">2</xref>

1970 • 32 citations

Activation of the cellular harvey ras gene in mouse skin tumors initiated with urethane

1989 • 27 citations

Comparison of the in vitro metabolisms and mutagenicities of dibenzo[a, c]anthracene, dibenzo[a, j]anthracene and dibenzo[a,j]anthracene: influence of norharman

1989 • 22 citations

Bacterial and mammalian cell mutagenicity of four optically active bay-region 3,4-diol-1,2-epoxides and other derivatives of the nitrogen heterocycle dibenz[c,h]acridine.

1986 • 21 citations

Metabolism of polycyclic aromatic hydrocarbons and phorbol esters by mouse skin: relevance to mechanism of action and trans-species/strain carcinogenesis.

1989 • 14 citations

Tumor-initiating activity of the bay-region dihydrodiols and diolepoxides of dibenz[a,j]anthracene and cholanthrene on mouse skin

1988 • 12 citations

Characterization of DNA adducts derived from (.+-.)-trans-3,4-dihydroxy-anti-1,2-epoxy-1,2,3,4-tetrahydrodibenz[a,j]anthracene and (.+-.)-7-methyl-trans-3,4-dihydroxy-anti-1,2-epoxy-1,2,3,4-tetrahydrodibenz[a,j]anthracene

1989 • 12 citations

Characterization of covalently modified deoxyribonucleosides formed from dibenz[a,j]anthracene in primary cultures of mouse keratinocytes

1991 • 11 citations